SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b6u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 7 TYR A 292
THR A  91
THR A 311
VAL A 278
 None
 1.18A 1tv8A-3b6uA:
undetectable		 1tv8A-3b6uA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 8 TYR A 292
THR A  91
THR A 311
VAL A 278
 None
 1.17A 2fb2A-3b6uA:
undetectable		 2fb2A-3b6uA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 7 TYR A 292
THR A  91
THR A 311
VAL A 278
 None
 1.18A 2fb2B-3b6uA:
undetectable		 2fb2B-3b6uA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 6 ARG A  78
VAL A  81
ILE A 126
TYR A  73
 None
 1.14A 2yfbB-3b6uA:
undetectable		 2yfbB-3b6uA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		5 / 12 ASN A 242
GLY A  90
VAL A  10
LEU A 305
ILE A 218
 None
 1.38A 3mnoA-3b6uA:
undetectable		 3mnoA-3b6uA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		5 / 12 ASN A 242
GLY A  90
VAL A  10
LEU A 305
ILE A 218
 None
 1.37A 3mnpA-3b6uA:
undetectable		 3mnpA-3b6uA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		3 / 3 VAL A 118
SER A 122
LEU A 243
 None
 0.53A 3n8xA-3b6uA:
undetectable		 3n8xA-3b6uA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 6 TYR A 138
ILE A 223
SER A 131
SER A 133
 None
 1.27A 3pmzD-3b6uA:
undetectable		 3pmzD-3b6uA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 8 ASN A 195
GLU A 107
TYR A 144
PHE A 219
 None
 1.15A 3rqwC-3b6uA:
undetectable
3rqwD-3b6uA:
undetectable		 3rqwC-3b6uA:
24.93
3rqwD-3b6uA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 8 GLU A 107
TYR A 144
PHE A 219
ASN A 195
 None
 1.15A 3rqwF-3b6uA:
undetectable
3rqwJ-3b6uA:
undetectable		 3rqwF-3b6uA:
24.93
3rqwJ-3b6uA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		3 / 3 GLY A  99
GLY A 101
THR A 103
 ADP  A 402 (-3.5A)
ADP  A 402 (-3.1A)
MG  A 401 ( 3.0A)
 0.44A 3si7B-3b6uA:
undetectable		 3si7B-3b6uA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		3 / 3 HIS A 129
HIS A 125
ILE A 126
 None
 0.79A 3u52A-3b6uA:
undetectable
3u52C-3b6uA:
undetectable		 3u52A-3b6uA:
19.22
3u52C-3b6uA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 5 TYR A 138
GLN A 136
ASP A  82
ASP A  74
 None
 1.40A 4qtuB-3b6uA:
undetectable		 4qtuB-3b6uA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 7 GLU A 107
TYR A 144
LEU A 156
PHE A 219
 None
 1.20A 4twdF-3b6uA:
undetectable
4twdJ-3b6uA:
undetectable		 4twdF-3b6uA:
24.35
4twdJ-3b6uA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		4 / 5 LEU A 139
PHE A 127
ILE A 223
ILE A 126
 None
 1.06A 5dzk4-3b6uA:
undetectable
5dzkg-3b6uA:
undetectable
5dzkm-3b6uA:
undetectable
5dzkn-3b6uA:
undetectable		 5dzk4-3b6uA:
1.18
5dzkg-3b6uA:
20.53
5dzkm-3b6uA:
19.10
5dzkn-3b6uA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_B_ASCB501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)		 3b6u KINESIN-LIKE PROTEIN
KIF3B
(Homo
sapiens) 		5 / 12 TYR A 138
HIS A 129
HIS A 125
ASP A  82
ILE A 223
 None
 1.48A 5zovB-3b6uA:
undetectable		 5zovB-3b6uA:
20.33