SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		3 / 3 ASP A  65
ASP A  36
ASP A  72
 UNX  A1003 (-4.8A)
None
None
 0.60A 1eizA-3b6vA:
undetectable		 1eizA-3b6vA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		3 / 3 ASP A  65
ASP A  36
ASP A  72
 UNX  A1003 (-4.8A)
None
None
 0.62A 1ej0A-3b6vA:
undetectable		 1ej0A-3b6vA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		4 / 7 TYR A 317
THR A  92
THR A 336
VAL A 303
 None
 1.09A 1tv8A-3b6vA:
undetectable		 1tv8A-3b6vA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		5 / 12 CYH A  17
LEU A  44
LEU A  33
ILE A  32
LEU A 356
 UNX  A1003 ( 4.6A)
None
None
None
None
 0.86A 1xdkF-3b6vA:
undetectable		 1xdkF-3b6vA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		4 / 8 TYR A 317
THR A  92
THR A 336
VAL A 303
 None
 1.10A 2fb2A-3b6vA:
undetectable		 2fb2A-3b6vA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		4 / 7 TYR A 317
THR A  92
THR A 336
VAL A 303
 None
 1.11A 2fb2B-3b6vA:
undetectable		 2fb2B-3b6vA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		4 / 8 GLY A 240
ILE A 219
VAL A 175
THR A  92
 None
 0.96A 2yoeB-3b6vA:
undetectable
2yoeC-3b6vA:
undetectable		 2yoeB-3b6vA:
21.74
2yoeC-3b6vA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		3 / 3 ASP A  65
ASP A  36
ASP A  72
 UNX  A1003 (-4.8A)
None
None
 0.53A 3douA-3b6vA:
undetectable		 3douA-3b6vA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		5 / 12 LEU A 146
GLN A 327
ILE A 304
LEU A 247
VAL A 245
 None
 1.05A 3gwxB-3b6vA:
undetectable		 3gwxB-3b6vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		5 / 10 VAL A  85
GLY A 240
VAL A  78
ASN A  90
GLY A  91
 None
 1.19A 3km6A-3b6vA:
undetectable		 3km6A-3b6vA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		5 / 9 VAL A  85
GLY A 240
VAL A  78
ASN A  90
GLY A  91
 None
 1.25A 3kmoA-3b6vA:
undetectable		 3kmoA-3b6vA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		5 / 9 ILE A  32
GLU A  24
GLN A  98
ARG A  18
LEU A  44
 None
 1.16A 3mjrA-3b6vA:
undetectable		 3mjrA-3b6vA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		3 / 3 GLY A 100
GLY A 102
THR A 104
 ADP  A1001 (-3.5A)
ADP  A1001 (-3.0A)
MG  A1002 ( 3.3A)
 0.40A 3si7B-3b6vA:
undetectable		 3si7B-3b6vA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		4 / 8 VAL A  93
ASN A 243
ILE A  82
MET A 107
 None
 1.10A 4iilA-3b6vA:
undetectable		 4iilA-3b6vA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		5 / 12 GLN A 108
ILE A 120
GLU A 147
LEU A 156
SER A 216
 None
 1.38A 4r88A-3b6vA:
undetectable		 4r88A-3b6vA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		5 / 12 GLN A 108
ILE A 120
GLU A 147
LEU A 156
SER A 216
 None
 1.39A 4r88C-3b6vA:
undetectable		 4r88C-3b6vA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		4 / 8 ILE A 148
VAL A 245
ILE A 221
LEU A 326
 None
 0.62A 5og9A-3b6vA:
undetectable		 5og9A-3b6vA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 3b6v KINESIN-LIKE PROTEIN
KIF3C
(Homo
sapiens) 		4 / 5 THR A 101
THR A  34
GLN A  31
ASP A  36
 ADP  A1001 (-4.9A)
None
UNX  A1003 ( 4.7A)
None
 1.42A 6ecxA-3b6vA:
undetectable		 6ecxA-3b6vA:
24.27