SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		4 / 6 PHE A 168
ILE A 188
THR A 153
THR A 133
 None
 1.03A 3mdrA-3b6yA:
undetectable		 3mdrA-3b6yA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		4 / 6 PHE A 168
ILE A 188
THR A 153
THR A 133
 None
 1.04A 3mdrB-3b6yA:
undetectable		 3mdrB-3b6yA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 9 PHE A  41
VAL A  74
THR A  78
ASP A   6
ILE A  62
 None
 1.20A 5lg3B-3b6yA:
undetectable		 5lg3B-3b6yA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 9 PHE A  41
VAL A  74
THR A  78
ASP A   6
ILE A  62
 None
 1.19A 5lg3C-3b6yA:
undetectable		 5lg3C-3b6yA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 9 PHE A  41
VAL A  74
THR A  78
ASP A   6
ILE A  62
 None
 1.19A 5lg3D-3b6yA:
undetectable		 5lg3D-3b6yA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 10 PHE A  41
VAL A  74
THR A  78
ASP A   6
ILE A  62
 None
 1.21A 5lg3F-3b6yA:
undetectable		 5lg3F-3b6yA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 10 PHE A  41
VAL A  74
THR A  78
ASP A   6
ILE A  62
 None
 1.19A 5lg3G-3b6yA:
undetectable		 5lg3G-3b6yA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 10 PHE A  41
VAL A  74
THR A  78
ASP A   6
ILE A  62
 None
 1.22A 5lg3H-3b6yA:
undetectable		 5lg3H-3b6yA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 12 PHE A  41
VAL A  74
THR A  78
ASP A   6
ILE A  62
 None
 1.21A 5lg3J-3b6yA:
undetectable		 5lg3J-3b6yA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 5 ALA A  32
VAL A  12
LYS A  51
PHE A  30
ILE A  60
 None
 1.15A 5of1A-3b6yA:
undetectable		 5of1A-3b6yA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3b6y GAMMA-INTERFERON-IND
UCIBLE PROTEIN
IFI-16
(Homo
sapiens) 		5 / 5 ALA A  15
VAL A  12
LYS A  51
PHE A  30
ILE A  60
 None
 1.48A 5of1B-3b6yA:
undetectable		 5of1B-3b6yA:
15.90