SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b70'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		5 / 11 PRO A  32
VAL A  90
VAL A  43
TYR A  40
GLY A  72
 None
 1.36A 1fkpA-3b70A:
undetectable		 1fkpA-3b70A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		5 / 11 PRO A  32
VAL A  90
VAL A  43
TYR A  40
GLY A  72
 None
 1.32A 1lwcA-3b70A:
2.2		 1lwcA-3b70A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 6 GLY A 208
GLN A 183
ALA A 204
SER A 206
 None
 0.88A 1p6kA-3b70A:
undetectable		 1p6kA-3b70A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 5 LEU A 360
GLY A 335
HIS A 338
ILE A 339
 None
 0.96A 1xf1A-3b70A:
undetectable		 1xf1A-3b70A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		5 / 12 LEU A 236
LEU A 185
GLY A 141
SER A 188
ALA A 135
 None
 1.13A 2bm9D-3b70A:
4.8		 2bm9D-3b70A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 7 ARG A 114
ASN A  49
PRO A 134
ALA A 135
 None
 1.37A 2ejgA-3b70A:
1.0		 2ejgA-3b70A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 7 ASP A 214
THR A 195
ILE A 239
ASN A 241
 None
None
NAP  A 372 ( 4.2A)
NAP  A 372 (-4.2A)
 1.26A 2jc9A-3b70A:
3.5		 2jc9A-3b70A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 7 LEU A 169
PHE A 247
ILE A 224
PHE A 213
 None
 0.93A 2opxA-3b70A:
3.4		 2opxA-3b70A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 7 ARG A  89
GLU A  44
ALA A 130
ALA A 131
 None
 1.05A 2zgwA-3b70A:
undetectable		 2zgwA-3b70A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		5 / 8 SER A 352
ILE A 239
SER A 174
SER A 197
GLY A 172
 NAP  A 372 (-2.6A)
NAP  A 372 ( 4.2A)
NAP  A 372 (-2.6A)
NAP  A 372 (-2.5A)
None
 1.41A 3lslA-3b70A:
undetectable
3lslD-3b70A:
undetectable		 3lslA-3b70A:
22.13
3lslD-3b70A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 8 ARG A  89
VAL A  90
ILE A  84
GLN A  85
 None
 1.02A 3remA-3b70A:
undetectable		 3remA-3b70A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 8 ARG A  89
VAL A  90
ILE A  84
GLN A  85
 None
 1.01A 3remB-3b70A:
undetectable		 3remB-3b70A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 7 SER A 138
THR A 284
ILE A 285
THR A 177
 None
None
None
NAP  A 372 (-3.5A)
 0.89A 4acaC-3b70A:
3.1		 4acaC-3b70A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 6 SER A 138
THR A 284
ILE A 285
THR A 177
 None
None
None
NAP  A 372 (-3.5A)
 1.01A 4acbC-3b70A:
3.2		 4acbC-3b70A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 6 THR A 175
ALA A 176
THR A 177
VAL A 180
 NAP  A 372 (-3.9A)
NAP  A 372 (-3.6A)
NAP  A 372 (-3.5A)
None
 0.62A 5ecoA-3b70A:
1.8		 5ecoA-3b70A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		5 / 9 ILE A 285
GLY A 141
LEU A 311
GLN A  94
LEU A 324
 None
 1.01A 5fhzB-3b70A:
3.9		 5fhzB-3b70A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qgjA-3b70A:
undetectable		 5qgjA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qglA-3b70A:
undetectable		 5qglA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.55A 5qgmA-3b70A:
undetectable		 5qgmA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.64A 5qgnA-3b70A:
undetectable		 5qgnA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.54A 5qguA-3b70A:
undetectable		 5qguA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qgvA-3b70A:
undetectable		 5qgvA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qgwA-3b70A:
undetectable		 5qgwA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qgxA-3b70A:
undetectable		 5qgxA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qgyA-3b70A:
undetectable		 5qgyA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.57A 5qgzA-3b70A:
undetectable		 5qgzA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.55A 5qh0A-3b70A:
undetectable		 5qh0A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.60A 5qh1A-3b70A:
undetectable		 5qh1A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qh2A-3b70A:
undetectable		 5qh2A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qh3A-3b70A:
undetectable		 5qh3A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.57A 5qh4A-3b70A:
undetectable		 5qh4A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.61A 5qh5A-3b70A:
undetectable		 5qh5A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qh6A-3b70A:
undetectable		 5qh6A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qh7A-3b70A:
undetectable		 5qh7A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.55A 5qh9A-3b70A:
undetectable		 5qh9A-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.52A 5qhaA-3b70A:
undetectable		 5qhaA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.54A 5qhcA-3b70A:
undetectable		 5qhcA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.55A 5qheA-3b70A:
undetectable		 5qheA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.58A 5qhfA-3b70A:
undetectable		 5qhfA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.59A 5qhgA-3b70A:
undetectable		 5qhgA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		3 / 3 VAL A  39
VAL A  77
GLN A  85
 None
 0.56A 5qhhA-3b70A:
undetectable		 5qhhA-3b70A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3b70 ENOYL REDUCTASE
(Aspergillus
terreus) 		4 / 6 GLN A 104
VAL A  43
MET A  55
PRO A  30
 None
 1.17A 6brdB-3b70A:
undetectable		 6brdB-3b70A:
13.39