SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b77'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_C_ROFC903_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3b77	UNCHARACTERIZED PROTEIN (Exiguobacterium sibiricum)	3 / 3	SER A 175 GLN A 176 PHE A 179	None	0.51A	3g4lC-3b77A: undetectable	3g4lC-3b77A: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_B_CGEB501_1 (CYTOCHROME P450 2B4)	3b77	UNCHARACTERIZED PROTEIN (Exiguobacterium sibiricum)	4 / 8	PHE A 89 ILE A 101 VAL A 18 VAL A 114	None	0.79A	3me6B-3b77A: undetectable	3me6B-3b77A: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PXM_B_ESTB2000_1 (ESTROGEN RECEPTOR)	3b77	UNCHARACTERIZED PROTEIN (Exiguobacterium sibiricum)	5 / 11	LEU A 59 ALA A 58 GLY A 38 HIS A 35 LEU A 34	None	1.17A	4pxmB-3b77A: undetectable	4pxmB-3b77A: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DX3_A_ESTA601_1 (ESTROGEN RECEPTOR)	3b77	UNCHARACTERIZED PROTEIN (Exiguobacterium sibiricum)	5 / 10	LEU A 59 ALA A 58 GLY A 38 HIS A 35 LEU A 34	None	1.19A	5dx3A-3b77A: undetectable	5dx3A-3b77A: 22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXG_B_ESTB601_1 (ESTROGEN RECEPTOR)	3b77	UNCHARACTERIZED PROTEIN (Exiguobacterium sibiricum)	5 / 11	LEU A 59 ALA A 58 GLY A 38 HIS A 35 LEU A 34	None	1.17A	5dxgB-3b77A: undetectable	5dxgB-3b77A: 22.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3G4L_C_ROFC903_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","3b77","UNCHARACTERIZED PROTEIN","Exiguobacterium sibiricum",3,"SER A 175;GLN A 176;PHE A 179","None","0.51A","3g4lC-3b77A:undetectable","3g4lC-3b77A:20.63"],["3ME6_B_CGEB501_1","CYTOCHROME P450 2B4","3b77","UNCHARACTERIZED PROTEIN","Exiguobacterium sibiricum",4,"PHE A  89;ILE A 101;VAL A  18;VAL A 114","None","0.79A","3me6B-3b77A:undetectable","3me6B-3b77A:19.32"],["4PXM_B_ESTB2000_1","ESTROGEN RECEPTOR","3b77","UNCHARACTERIZED PROTEIN","Exiguobacterium sibiricum",5,"LEU A  59;ALA A  58;GLY A  38;HIS A  35;LEU A  34","None","1.17A","4pxmB-3b77A:undetectable","4pxmB-3b77A:22.14"],["5DX3_A_ESTA601_1","ESTROGEN RECEPTOR","3b77","UNCHARACTERIZED PROTEIN","Exiguobacterium sibiricum",5,"LEU A  59;ALA A  58;GLY A  38;HIS A  35;LEU A  34","None","1.19A","5dx3A-3b77A:undetectable","5dx3A-3b77A:22.75"],["5DXG_B_ESTB601_1","ESTROGEN RECEPTOR","3b77","UNCHARACTERIZED PROTEIN","Exiguobacterium sibiricum",5,"LEU A  59;ALA A  58;GLY A  38;HIS A  35;LEU A  34","None","1.17A","5dxgB-3b77A:undetectable","5dxgB-3b77A:22.75"]]