SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LWF_A_NVPA999_1 (HIV-1 REVERSE TRANSCRIPTASE)	3b7c	UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	5 / 9	LEU A 67 TYR A 54 TYR A 58 GLY A 20 LEU A 90	None None None EDO A 124 (-4.2A) None	1.29A	1lwfA-3b7cA: undetectable	1lwfA-3b7cA: 11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZR_B_CDXB901_1 (DNA TOPOISOMERASE II)	3b7c	UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	4 / 7	THR A 50 TYR A 54 TYR A 58 LEU A 22	None None None EDO A 124 ( 4.1A)	1.13A	1qzrA-3b7cA: undetectable	1qzrA-3b7cA: 14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YC2_B_NCAB508_0 (NAD-DEPENDENT DEACETYLASE 2)	3b7c	UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	4 / 5	LEU A 37 TYR A 29 GLN A 13 TYR A 54	None EDO A 128 (-4.9A) EDO A 128 (-3.1A) None	1.11A	1yc2B-3b7cA: undetectable 1yc2C-3b7cA: undetectable	1yc2B-3b7cA: 19.38 1yc2C-3b7cA: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ARC_A_LEUA1001_0 (LEUCINE--TRNA LIGASE)	3b7c	UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	4 / 7	LEU A 103 TYR A 29 ASP A 117 SER A 119	EDO A 128 ( 4.8A) EDO A 128 (-4.9A) EDO A 128 (-3.2A) EDO A 128 ( 3.7A)	1.31A	4arcA-3b7cA: undetectable	4arcA-3b7cA: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I9Y_A_1N1A1001_2 (EPHRIN TYPE-A RECEPTOR 2)	3b7c	UNCHARACTERIZED PROTEIN (Shewanella oneidensis)	3 / 3	ILE A 6 ILE A 114 MET A 76	None	0.57A	5i9yA-3b7cA: 2.2	5i9yA-3b7cA: 17.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LWF_A_NVPA999_1","HIV-1 REVERSE TRANSCRIPTASE","3b7c","UNCHARACTERIZED PROTEIN","Shewanella oneidensis",5,"LEU A  67;TYR A  54;TYR A  58;GLY A  20;LEU A  90","None;None;None;EDO A 124 (-4.2A);None","1.29A","1lwfA-3b7cA:undetectable","1lwfA-3b7cA:11.59"],["1QZR_B_CDXB901_1","DNA TOPOISOMERASE II;DNA TOPOISOMERASE II","3b7c","UNCHARACTERIZED PROTEIN","Shewanella oneidensis",4,"THR A  50;TYR A  54;TYR A  58;LEU A  22","None;None;None;EDO A 124 ( 4.1A)","1.13A","1qzrA-3b7cA:undetectable","1qzrA-3b7cA:14.25"],["1YC2_B_NCAB508_0","NAD-DEPENDENT DEACETYLASE 2","3b7c","UNCHARACTERIZED PROTEIN","Shewanella oneidensis",4,"LEU A  37;TYR A  29;GLN A  13;TYR A  54","None;EDO A 128 (-4.9A);EDO A 128 (-3.1A);None","1.11A","1yc2B-3b7cA:undetectable;1yc2C-3b7cA:undetectable","1yc2B-3b7cA:19.38;1yc2C-3b7cA:19.38"],["4ARC_A_LEUA1001_0","LEUCINE--TRNA LIGASE","3b7c","UNCHARACTERIZED PROTEIN","Shewanella oneidensis",4,"LEU A 103;TYR A  29;ASP A 117;SER A 119","EDO A 128 ( 4.8A);EDO A 128 (-4.9A);EDO A 128 (-3.2A);EDO A 128 ( 3.7A)","1.31A","4arcA-3b7cA:undetectable","4arcA-3b7cA:9.69"],["5I9Y_A_1N1A1001_2","EPHRIN TYPE-A RECEPTOR 2","3b7c","UNCHARACTERIZED PROTEIN","Shewanella oneidensis",3,"ILE A   6;ILE A 114;MET A  76","None","0.57A","5i9yA-3b7cA:2.2","5i9yA-3b7cA:17.26"]]