SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 3b7m CELLULASE
(Rhodothermus
marinus) 		4 / 8 LEU A   5
GLY A 196
VAL A  36
ILE A  34
 None
 0.70A 1d4yB-3b7mA:
undetectable		 1d4yB-3b7mA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3b7m CELLULASE
(Rhodothermus
marinus) 		5 / 12 ILE A 117
LEU A 119
ILE A  98
VAL A 215
PHE A 211
 None
 1.16A 2ygpA-3b7mA:
undetectable		 2ygpA-3b7mA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 3b7m CELLULASE
(Rhodothermus
marinus) 		3 / 3 ARG A  79
ILE A 117
THR A 161
 None
 0.65A 3ia4D-3b7mA:
undetectable		 3ia4D-3b7mA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 3b7m CELLULASE
(Rhodothermus
marinus) 		5 / 12 ASN A 120
GLY A 123
ALA A 204
GLY A 205
GLN A  32
 None
 1.19A 3v3oA-3b7mA:
undetectable		 3v3oA-3b7mA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3b7m CELLULASE
(Rhodothermus
marinus) 		4 / 5 PHE A  43
PHE A 197
ILE A  45
GLY A 205
 None
 1.02A 4ejjC-3b7mA:
undetectable		 4ejjC-3b7mA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3b7m CELLULASE
(Rhodothermus
marinus) 		5 / 12 LEU A  75
ILE A 175
ALA A 101
TRP A 188
GLY A 111
 None
 1.03A 4enhA-3b7mA:
undetectable		 4enhA-3b7mA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3b7m CELLULASE
(Rhodothermus
marinus) 		3 / 3 THR A  13
THR A  20
PHE A  64
 None
 0.87A 5cxvA-3b7mA:
undetectable		 5cxvA-3b7mA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 3b7m CELLULASE
(Rhodothermus
marinus) 		5 / 11 LEU A   5
ASN A  23
GLY A 196
VAL A  36
ILE A  34
 None
 1.08A 5kr2B-3b7mA:
undetectable		 5kr2B-3b7mA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 3b7m CELLULASE
(Rhodothermus
marinus) 		5 / 9 LEU A   5
ASN A  23
GLY A 196
VAL A  36
ILE A  34
 None
 1.10A 5kr2D-3b7mA:
undetectable		 5kr2D-3b7mA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3b7m CELLULASE
(Rhodothermus
marinus) 		4 / 7 ASN A  42
PHE A  43
THR A  80
ILE A  62
 None
 0.89A 5nzyA-3b7mA:
undetectable		 5nzyA-3b7mA:
22.74