SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9H_A_RAPA108_1 (FKBP12.6)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.87A	1c9hA-3b7xA: 15.3	1c9hA-3b7xA: 29.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DVX_B_DIFB125_1 (TRANSTHYRETIN)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	4 / 7	LYS A 113 LEU A 111 LEU A 134 SER A 62	None	0.99A	1dvxA-3b7xA: undetectable	1dvxA-3b7xA: 23.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1FAP_A_RAPA108_1 (FK506-BINDING PROTEIN)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.83A	1fapA-3b7xA: 15.2	1fapA-3b7xA: 31.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1FKF_A_FK5A108_1 (FK506 BINDING PROTEIN)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.90A	1fkfA-3b7xA: 15.0	1fkfA-3b7xA: 31.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1FKJ_A_FK5A108_1 (FK506 BINDING PROTEIN)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.93A	1fkjA-3b7xA: 15.0	1fkjA-3b7xA: 31.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1PBK_A_RAPA225_1 (FKBP25)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.88A	1pbkA-3b7xA: 14.9	1pbkA-3b7xA: 31.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q6I_A_FK5A301_1 (FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 9	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.89A	1q6iA-3b7xA: 15.7	1q6iA-3b7xA: 25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q6I_B_FK5B401_1 (FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.82A	1q6iB-3b7xA: 15.5	1q6iB-3b7xA: 25.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TCO_C_FK5C509_2 (FK506-BINDING PROTEIN)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.95A	1tcoC-3b7xA: 14.7	1tcoC-3b7xA: 32.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YAT_A_FK5A108_1 (FK506 BINDING PROTEIN)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.90A	1yatA-3b7xA: 16.1	1yatA-3b7xA: 31.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2FKE_A_FK5A108_1 (FK506 BINDING PROTEIN)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.93A	2fkeA-3b7xA: 15.1	2fkeA-3b7xA: 31.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VN1_A_FK5A501_1 (70 KDA PEPTIDYLPROLYL ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	6 / 11	TYR A 61 ASP A 73 TYR A 118 CYH A 123 ILE A 127 PHE A 135	None	1.09A	2vn1A-3b7xA: 16.7	2vn1A-3b7xA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VN1_A_FK5A501_1 (70 KDA PEPTIDYLPROLYL ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	6 / 11	TYR A 61 PHE A 72 ASP A 73 CYH A 123 ILE A 127 PHE A 135	None	1.01A	2vn1A-3b7xA: 16.7	2vn1A-3b7xA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3IHZ_A_FK5A501_1 (70 KDA PEPTIDYLPROLYL ISOMERASE, PUTATIVE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.92A	3ihzA-3b7xA: 16.5	3ihzA-3b7xA: 33.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_B_TFPB201_1 (PROTEIN S100-A4)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	4 / 8	GLY A 105 ILE A 43 PHE A 135 PHE A 112	None	1.03A	3ko0B-3b7xA: undetectable 3ko0J-3b7xA: undetectable	3ko0B-3b7xA: 20.53 3ko0J-3b7xA: 20.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3KZ7_A_RAPA225_1 (FK506-BINDING PROTEIN 3)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.90A	3kz7A-3b7xA: 15.0	3kz7A-3b7xA: 31.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3O5R_A_FK5A1001_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.92A	3o5rA-3b7xA: 18.2	3o5rA-3b7xA: 38.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UF8_A_FK5A114_1 (UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.90A	3uf8A-3b7xA: 15.6	3uf8A-3b7xA: 24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UQA_A_FK5A114_1 (UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.96A	3uqaA-3b7xA: 15.8	3uqaA-3b7xA: 24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UQB_A_FK5A114_1 (UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	4 / 8	TYR A 61 TYR A 118 ILE A 127 PHE A 135	None	0.82A	3uqbA-3b7xA: 15.7	3uqbA-3b7xA: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAW_A_FK5A114_1 (UBIQUITIN-LIKE PROTEIN SMT3,PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.99A	3vawA-3b7xA: 15.5	3vawA-3b7xA: 24.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DRH_A_RAPA201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.87A	4drhA-3b7xA: 17.4	4drhA-3b7xA: 37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DRH_D_RAPD201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.88A	4drhD-3b7xA: 17.3	4drhD-3b7xA: 37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DRI_A_RAPA201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.93A	4driA-3b7xA: 17.7	4driA-3b7xA: 37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DRJ_A_RAPA201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 GLU A 96 TYR A 118 ILE A 127	None	1.22A	4drjA-3b7xA: 17.5	4drjA-3b7xA: 37.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DRJ_A_RAPA201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.90A	4drjA-3b7xA: 17.5	4drjA-3b7xA: 37.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DZ2_A_FK5A200_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.92A	4dz2A-3b7xA: 15.7 4dz2B-3b7xA: 15.7	4dz2A-3b7xA: 28.79 4dz2B-3b7xA: 28.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DZ2_B_FK5B200_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.91A	4dz2A-3b7xA: 15.7 4dz2B-3b7xA: 15.7	4dz2A-3b7xA: 28.79 4dz2B-3b7xA: 28.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DZ3_A_FK5A201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.95A	4dz3A-3b7xA: 15.8	4dz3A-3b7xA: 28.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DZ3_B_FK5B201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.94A	4dz3B-3b7xA: 15.8	4dz3B-3b7xA: 28.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4NNR_A_FK5A201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.97A	4nnrA-3b7xA: 11.5 4nnrB-3b7xA: 11.6	4nnrA-3b7xA: 31.79 4nnrB-3b7xA: 31.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4NNR_B_FK5B201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.94A	4nnrB-3b7xA: 11.6	4nnrB-3b7xA: 31.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4QT3_A_RAPA202_1 (FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 GLU A 96 TYR A 118 ILE A 127	None	1.26A	4qt3A-3b7xA: 16.5	4qt3A-3b7xA: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4QT3_A_RAPA202_1 (FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.86A	4qt3A-3b7xA: 16.5	4qt3A-3b7xA: 33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z2E_F_TR6F101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B SYMMETRIZED E-SITE DNA)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	4 / 5	GLY A 48 ARG A 103 GLY A 46 GLU A 106	None	1.24A	4z2eB-3b7xA: undetectable 4z2eC-3b7xA: undetectable	4z2eB-3b7xA: 16.63 4z2eC-3b7xA: 19.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5B8I_C_FK5C201_3 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.89A	5b8iC-3b7xA: 14.4	5b8iC-3b7xA: 33.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSW_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	3 / 3	PHE A 110 ILE A 137 ASP A 73	None	0.45A	5cswA-3b7xA: undetectable	5cswA-3b7xA: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSW_B_P06B801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	3 / 3	PHE A 110 ILE A 137 ASP A 73	None	0.51A	5cswB-3b7xA: undetectable	5cswB-3b7xA: 19.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5D75_A_FK5A301_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.90A	5d75A-3b7xA: 14.9	5d75A-3b7xA: 30.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5GPG_A_RAPA301_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.90A	5gpgA-3b7xA: 15.7	5gpgA-3b7xA: 31.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_B_FK5B201_1 (FK506-BINDING PROTEIN 1)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.81A	5hw8B-3b7xA: 13.6	5hw8B-3b7xA: 27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_D_FK5D201_1 (FK506-BINDING PROTEIN 1)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.93A	5hw8D-3b7xA: 13.6	5hw8D-3b7xA: 27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_G_FK5G201_2 (FK506-BINDING PROTEIN 1)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.78A	5hw8G-3b7xA: 13.4	5hw8G-3b7xA: 27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HWC_A_FK5A201_1 (FK506-BINDING PROTEIN 1A)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 11	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.93A	5hwcA-3b7xA: 14.9	5hwcA-3b7xA: 29.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_A_FK5A201_0 (PEPTIDYLPROLYL ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.96A	6mkeA-3b7xA: 16.9 6mkeD-3b7xA: 16.7	6mkeA-3b7xA: 21.48 6mkeD-3b7xA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_B_FK5B201_0 (PEPTIDYLPROLYL ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 12	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.95A	6mkeB-3b7xA: 16.8 6mkeC-3b7xA: 16.7	6mkeB-3b7xA: 21.48 6mkeC-3b7xA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_C_FK5C201_1 (PEPTIDYLPROLYL ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.91A	6mkeC-3b7xA: 16.7	6mkeC-3b7xA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_D_FK5D201_1 (PEPTIDYLPROLYL ISOMERASE)	3b7x	FK506-BINDING PROTEIN 6 (Homo sapiens)	5 / 10	TYR A 61 ASP A 73 TYR A 118 ILE A 127 PHE A 135	None	0.94A	6mkeD-3b7xA: 16.7	6mkeD-3b7xA: 21.48

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C9H_A_RAPA108_1","FKBP12.6","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.87A","1c9hA-3b7xA:15.3","1c9hA-3b7xA:29.10"],["1DVX_B_DIFB125_1","TRANSTHYRETIN;TRANSTHYRETIN","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",4,"LYS A 113;LEU A 111;LEU A 134;SER A  62","None","0.99A","1dvxA-3b7xA:undetectable","1dvxA-3b7xA:23.91"],["1FAP_A_RAPA108_1","FK506-BINDING PROTEIN","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.83A","1fapA-3b7xA:15.2","1fapA-3b7xA:31.34"],["1FKF_A_FK5A108_1","FK506 BINDING PROTEIN","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.90A","1fkfA-3b7xA:15.0","1fkfA-3b7xA:31.34"],["1FKJ_A_FK5A108_1","FK506 BINDING PROTEIN","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.93A","1fkjA-3b7xA:15.0","1fkjA-3b7xA:31.34"],["1PBK_A_RAPA225_1","FKBP25","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.88A","1pbkA-3b7xA:14.9","1pbkA-3b7xA:31.16"],["1Q6I_A_FK5A301_1","FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.89A","1q6iA-3b7xA:15.7","1q6iA-3b7xA:25.88"],["1Q6I_B_FK5B401_1","FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.82A","1q6iB-3b7xA:15.5","1q6iB-3b7xA:25.88"],["1TCO_C_FK5C509_2","FK506-BINDING PROTEIN","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.95A","1tcoC-3b7xA:14.7","1tcoC-3b7xA:32.09"],["1YAT_A_FK5A108_1","FK506 BINDING PROTEIN","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.90A","1yatA-3b7xA:16.1","1yatA-3b7xA:31.85"],["2FKE_A_FK5A108_1","FK506 BINDING PROTEIN","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.93A","2fkeA-3b7xA:15.1","2fkeA-3b7xA:31.34"],["2VN1_A_FK5A501_1","70 KDA PEPTIDYLPROLYL ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",6,"TYR A  61;ASP A  73;TYR A 118;CYH A 123;ILE A 127;PHE A 135","None","1.09A","2vn1A-3b7xA:16.7","2vn1A-3b7xA:33.33"],["2VN1_A_FK5A501_1","70 KDA PEPTIDYLPROLYL ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",6,"TYR A  61;PHE A  72;ASP A  73;CYH A 123;ILE A 127;PHE A 135","None","1.01A","2vn1A-3b7xA:16.7","2vn1A-3b7xA:33.33"],["3IHZ_A_FK5A501_1","70 KDA PEPTIDYLPROLYL ISOMERASE, PUTATIVE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.92A","3ihzA-3b7xA:16.5","3ihzA-3b7xA:33.58"],["3KO0_B_TFPB201_1","PROTEIN S100-A4;PROTEIN S100-A4","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",4,"GLY A 105;ILE A  43;PHE A 135;PHE A 112","None","1.03A","3ko0B-3b7xA:undetectable;3ko0J-3b7xA:undetectable","3ko0B-3b7xA:20.53;3ko0J-3b7xA:20.53"],["3KZ7_A_RAPA225_1","FK506-BINDING PROTEIN 3","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.90A","3kz7A-3b7xA:15.0","3kz7A-3b7xA:31.21"],["3O5R_A_FK5A1001_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.92A","3o5rA-3b7xA:18.2","3o5rA-3b7xA:38.97"],["3UF8_A_FK5A114_1","UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.90A","3uf8A-3b7xA:15.6","3uf8A-3b7xA:24.88"],["3UQA_A_FK5A114_1","UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.96A","3uqaA-3b7xA:15.8","3uqaA-3b7xA:24.88"],["3UQB_A_FK5A114_1","UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",4,"TYR A  61;TYR A 118;ILE A 127;PHE A 135","None","0.82A","3uqbA-3b7xA:15.7","3uqbA-3b7xA:24.40"],["3VAW_A_FK5A114_1","UBIQUITIN-LIKE PROTEIN SMT3,PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.99A","3vawA-3b7xA:15.5","3vawA-3b7xA:24.88"],["4DRH_A_RAPA201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.87A","4drhA-3b7xA:17.4","4drhA-3b7xA:37.50"],["4DRH_D_RAPD201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.88A","4drhD-3b7xA:17.3","4drhD-3b7xA:37.50"],["4DRI_A_RAPA201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.93A","4driA-3b7xA:17.7","4driA-3b7xA:37.50"],["4DRJ_A_RAPA201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;GLU A  96;TYR A 118;ILE A 127","None","1.22A","4drjA-3b7xA:17.5","4drjA-3b7xA:37.67"],["4DRJ_A_RAPA201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.90A","4drjA-3b7xA:17.5","4drjA-3b7xA:37.67"],["4DZ2_A_FK5A200_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.92A","4dz2A-3b7xA:15.7;4dz2B-3b7xA:15.7","4dz2A-3b7xA:28.79;4dz2B-3b7xA:28.79"],["4DZ2_B_FK5B200_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.91A","4dz2A-3b7xA:15.7;4dz2B-3b7xA:15.7","4dz2A-3b7xA:28.79;4dz2B-3b7xA:28.79"],["4DZ3_A_FK5A201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.95A","4dz3A-3b7xA:15.8","4dz3A-3b7xA:28.79"],["4DZ3_B_FK5B201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.94A","4dz3B-3b7xA:15.8","4dz3B-3b7xA:28.79"],["4NNR_A_FK5A201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.97A","4nnrA-3b7xA:11.5;4nnrB-3b7xA:11.6","4nnrA-3b7xA:31.79;4nnrB-3b7xA:31.79"],["4NNR_B_FK5B201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.94A","4nnrB-3b7xA:11.6","4nnrB-3b7xA:31.79"],["4QT3_A_RAPA202_1","FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;GLU A  96;TYR A 118;ILE A 127","None","1.26A","4qt3A-3b7xA:16.5","4qt3A-3b7xA:33.33"],["4QT3_A_RAPA202_1","FK506-BINDING PROTEIN (FKBP)-TYPE PEPTIDYL-PROPYL ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.86A","4qt3A-3b7xA:16.5","4qt3A-3b7xA:33.33"],["4Z2E_F_TR6F101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;SYMMETRIZED E-SITE DNA","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",4,"GLY A  48;ARG A 103;GLY A  46;GLU A 106","None","1.24A","4z2eB-3b7xA:undetectable;4z2eC-3b7xA:undetectable","4z2eB-3b7xA:16.63;4z2eC-3b7xA:19.48"],["5B8I_C_FK5C201_3","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.89A","5b8iC-3b7xA:14.4","5b8iC-3b7xA:33.09"],["5CSW_A_P06A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",3,"PHE A 110;ILE A 137;ASP A  73","None","0.45A","5cswA-3b7xA:undetectable","5cswA-3b7xA:19.79"],["5CSW_B_P06B801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",3,"PHE A 110;ILE A 137;ASP A  73","None","0.51A","5cswB-3b7xA:undetectable","5cswB-3b7xA:19.79"],["5D75_A_FK5A301_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.90A","5d75A-3b7xA:14.9","5d75A-3b7xA:30.94"],["5GPG_A_RAPA301_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.90A","5gpgA-3b7xA:15.7","5gpgA-3b7xA:31.11"],["5HW8_B_FK5B201_1","FK506-BINDING PROTEIN 1","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.81A","5hw8B-3b7xA:13.6","5hw8B-3b7xA:27.89"],["5HW8_D_FK5D201_1","FK506-BINDING PROTEIN 1","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.93A","5hw8D-3b7xA:13.6","5hw8D-3b7xA:27.89"],["5HW8_G_FK5G201_2","FK506-BINDING PROTEIN 1","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.78A","5hw8G-3b7xA:13.4","5hw8G-3b7xA:27.89"],["5HWC_A_FK5A201_1","FK506-BINDING PROTEIN 1A","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.93A","5hwcA-3b7xA:14.9","5hwcA-3b7xA:29.63"],["6MKE_A_FK5A201_0","PEPTIDYLPROLYL ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.96A","6mkeA-3b7xA:16.9;6mkeD-3b7xA:16.7","6mkeA-3b7xA:21.48;6mkeD-3b7xA:21.48"],["6MKE_B_FK5B201_0","PEPTIDYLPROLYL ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.95A","6mkeB-3b7xA:16.8;6mkeC-3b7xA:16.7","6mkeB-3b7xA:21.48;6mkeC-3b7xA:21.48"],["6MKE_C_FK5C201_1","PEPTIDYLPROLYL ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.91A","6mkeC-3b7xA:16.7","6mkeC-3b7xA:21.48"],["6MKE_D_FK5D201_1","PEPTIDYLPROLYL ISOMERASE","3b7x","FK506-BINDING PROTEIN 6","Homo sapiens",5,"TYR A  61;ASP A  73;TYR A 118;ILE A 127;PHE A 135","None","0.94A","6mkeD-3b7xA:16.7","6mkeD-3b7xA:21.48"]]