SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3b85 PHOSPHATE
STARVATION-INDUCIBLE
PROTEIN
(Corynebacterium
glutamicum) 		4 / 4 SER A 145
GLY A 146
HIS A 297
ASP A 295
 SO4  A 401 (-4.9A)
SO4  A 401 (-3.2A)
None
None
 1.40A 2oxtC-3b85A:
undetectable		 2oxtC-3b85A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 3b85 PHOSPHATE
STARVATION-INDUCIBLE
PROTEIN
(Corynebacterium
glutamicum) 		4 / 8 ALA A 201
MET A 205
PHE A 237
VAL A 137
 SO4  A 409 ( 4.1A)
None
None
None
 1.04A 4ltwA-3b85A:
undetectable		 4ltwA-3b85A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3b85 PHOSPHATE
STARVATION-INDUCIBLE
PROTEIN
(Corynebacterium
glutamicum) 		5 / 9 ARG A 231
THR A 170
LEU A 240
VAL A 266
MET A 264
 None
 1.00A 4mjrA-3b85A:
undetectable		 4mjrA-3b85A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 3b85 PHOSPHATE
STARVATION-INDUCIBLE
PROTEIN
(Corynebacterium
glutamicum) 		5 / 12 LEU A 301
GLY A 144
PHE A 237
VAL A 265
ILE A 131
 None
SO4  A 401 (-3.2A)
None
None
None
 1.11A 5tuiB-3b85A:
undetectable		 5tuiB-3b85A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_ACTA404_0
(FERREDOXIN--NADP
REDUCTASE)		 3b85 PHOSPHATE
STARVATION-INDUCIBLE
PROTEIN
(Corynebacterium
glutamicum) 		4 / 4 THR A 170
TYR A 227
LEU A 225
MET A 228
 None
None
SO4  A 408 ( 4.7A)
None
 1.35A 5vw9A-3b85A:
0.0		 5vw9A-3b85A:
22.61