SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 6 PRO A 228
MET A 188
ALA A 187
GLU A 180
 None
 1.44A 1qhyA-3b89A:
undetectable		 1qhyA-3b89A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 THR A  84
VAL A  74
VAL A 139
ILE A 140
 None
 0.83A 1t87B-3b89A:
undetectable		 1t87B-3b89A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 ALA A  77
LEU A  69
ALA A  68
VAL A 127
CYH A 112
 None
 1.09A 1xdkA-3b89A:
undetectable		 1xdkA-3b89A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 GLY A 113
LEU A 136
ASP A 157
VAL A 158
LEU A 175
 5GP  A 500 ( 4.5A)
None
5GP  A 500 (-2.7A)
5GP  A 500 (-3.6A)
5GP  A 500 ( 4.7A)
 0.86A 1zq9B-3b89A:
11.5		 1zq9B-3b89A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 10 LEU A 176
LEU A 191
LEU A 194
ILE A 110
ALA A 200
 None
 1.04A 2bxeB-3b89A:
3.0		 2bxeB-3b89A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 LEU A 176
LEU A 191
LEU A 194
ILE A 110
ALA A 200
 None
 1.01A 2bxpA-3b89A:
2.6		 2bxpA-3b89A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 ASP A 109
GLY A 113
ILE A 132
LEU A 175
LEU A 179
 None
5GP  A 500 ( 4.5A)
5GP  A 500 (-4.1A)
5GP  A 500 ( 4.7A)
None
 0.79A 2nxeA-3b89A:
12.8		 2nxeA-3b89A:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 8 THR A  84
VAL A  74
VAL A 139
ILE A 140
 None
 0.89A 2qbmA-3b89A:
undetectable		 2qbmA-3b89A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 ALA A 111
GLY A 113
ASP A 131
ASP A 157
 5GP  A 500 (-3.1A)
5GP  A 500 ( 4.5A)
5GP  A 500 (-3.1A)
5GP  A 500 (-2.7A)
 0.51A 2uyqA-3b89A:
10.3		 2uyqA-3b89A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 ASP A 150
ARG A 105
VAL A 107
ARG A 106
 None
 1.15A 2yfbA-3b89A:
undetectable		 2yfbA-3b89A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 ALA A  82
GLU A  86
ARG A 206
GLY A  51
HIS A  50
 None
 1.21A 2yjaB-3b89A:
undetectable		 2yjaB-3b89A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 10 GLY A 113
ASP A 131
ILE A 132
ASP A 157
LEU A 175
 5GP  A 500 ( 4.5A)
5GP  A 500 (-3.1A)
5GP  A 500 (-4.1A)
5GP  A 500 (-2.7A)
5GP  A 500 ( 4.7A)
 0.78A 3ay0B-3b89A:
12.7		 3ay0B-3b89A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 10 GLY A 113
ASP A 131
ILE A 132
ASP A 157
VAL A 158
 5GP  A 500 ( 4.5A)
5GP  A 500 (-3.1A)
5GP  A 500 (-4.1A)
5GP  A 500 (-2.7A)
5GP  A 500 (-3.6A)
 0.72A 3ay0B-3b89A:
12.7		 3ay0B-3b89A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 LEU A  91
LEU A 171
LEU A 119
PRO A 104
THR A  84
 None
 1.10A 3dfrA-3b89A:
2.1		 3dfrA-3b89A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 11 ILE A 172
GLN A 192
TRP A 222
LEU A 194
ILE A 244
 None
 0.99A 3fc6A-3b89A:
undetectable		 3fc6A-3b89A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 HIS A  81
SER A  83
GLY A 113
ILE A 132
LYS A 174
 5GP  A 500 (-4.7A)
5GP  A 500 (-2.7A)
5GP  A 500 ( 4.5A)
5GP  A 500 (-4.1A)
5GP  A 500 (-4.9A)
 0.98A 3fzgA-3b89A:
21.6		 3fzgA-3b89A:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 SER A  83
THR A  84
GLY A 113
ILE A 132
LYS A 174
 5GP  A 500 (-2.7A)
None
5GP  A 500 ( 4.5A)
5GP  A 500 (-4.1A)
5GP  A 500 (-4.9A)
 0.96A 3fzgA-3b89A:
21.6		 3fzgA-3b89A:
27.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 ARG A  26
ALA A 111
ILE A 132
ASP A 157
LEU A 171
 None
5GP  A 500 (-3.1A)
5GP  A 500 (-4.1A)
5GP  A 500 (-2.7A)
None
 0.97A 3lcvB-3b89A:
27.3		 3lcvB-3b89A:
34.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		8 / 12 ARG A  26
HIS A  81
SER A  83
THR A  84
ALA A 111
ILE A 132
ASP A 157
LYS A 174
 None
5GP  A 500 (-4.7A)
5GP  A 500 (-2.7A)
None
5GP  A 500 (-3.1A)
5GP  A 500 (-4.1A)
5GP  A 500 (-2.7A)
5GP  A 500 (-4.9A)
 0.86A 3lcvB-3b89A:
27.3		 3lcvB-3b89A:
34.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 8 ARG A 181
LEU A 176
LEU A 159
ILE A 172
 None
None
5GP  A 500 ( 4.3A)
None
 0.88A 3ln1A-3b89A:
undetectable		 3ln1A-3b89A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 ARG A 181
LEU A 176
LEU A 159
ILE A 172
 None
None
5GP  A 500 ( 4.3A)
None
 0.87A 3ln1B-3b89A:
undetectable		 3ln1B-3b89A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		3 / 3 GLY A 113
ASP A 131
ASP A 157
 5GP  A 500 ( 4.5A)
5GP  A 500 (-3.1A)
5GP  A 500 (-2.7A)
 0.43A 3ou7C-3b89A:
13.6		 3ou7C-3b89A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 PRO A 104
ILE A  98
LEU A  94
ASN A 115
 None
 0.96A 3p50A-3b89A:
undetectable		 3p50A-3b89A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 PRO A 104
ILE A  98
LEU A  94
ASN A 115
 None
 0.96A 3p50B-3b89A:
undetectable		 3p50B-3b89A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 PRO A 104
ILE A  98
LEU A  94
ASN A 115
 None
 0.95A 3p50C-3b89A:
undetectable		 3p50C-3b89A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 PRO A 104
ILE A  98
LEU A  94
ASN A 115
 None
 0.95A 3p50D-3b89A:
undetectable		 3p50D-3b89A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 PRO A 104
ILE A  98
LEU A  94
ASN A 115
 None
 0.95A 3p50E-3b89A:
undetectable		 3p50E-3b89A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 11 ALA A  82
GLU A  86
ARG A 206
GLY A  51
HIS A  50
 None
 1.21A 3uudA-3b89A:
undetectable		 3uudA-3b89A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 11 GLY A 113
ASP A 131
ASP A 157
VAL A 158
LEU A 179
 5GP  A 500 ( 4.5A)
5GP  A 500 (-3.1A)
5GP  A 500 (-2.7A)
5GP  A 500 (-3.6A)
None
 0.77A 3v8vB-3b89A:
5.2		 3v8vB-3b89A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 7 GLN A  40
VAL A  42
GLU A  43
ARG A  46
 None
 1.23A 4mv7A-3b89A:
4.4		 4mv7A-3b89A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 8 PRO A 163
LEU A 190
VAL A 201
LEU A 175
 None
None
None
5GP  A 500 ( 4.7A)
 0.87A 4pwdA-3b89A:
2.4		 4pwdA-3b89A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 11 ALA A  82
GLU A  86
ARG A 206
GLY A  51
HIS A  50
 None
 1.22A 4pxmB-3b89A:
undetectable		 4pxmB-3b89A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 ASP A 131
LEU A 155
LEU A  69
GLY A 135
ALA A  18
 5GP  A 500 (-3.1A)
None
None
None
None
 1.23A 4retA-3b89A:
2.2		 4retA-3b89A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 ASP A 131
LEU A 155
LEU A  69
GLY A 135
ALA A  18
 5GP  A 500 (-3.1A)
None
None
None
None
 1.23A 4retC-3b89A:
2.2		 4retC-3b89A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 12 GLU A 180
ILE A 233
LEU A 227
GLY A 226
GLY A 225
 None
 1.09A 4yvgA-3b89A:
undetectable		 4yvgA-3b89A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 6 LEU A 136
PRO A 142
PHE A 143
GLU A 146
 None
 1.22A 5b8iA-3b89A:
undetectable		 5b8iA-3b89A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 10 ALA A  82
GLU A  86
ARG A 206
GLY A  51
HIS A  50
 None
 1.19A 5dx3A-3b89A:
undetectable		 5dx3A-3b89A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 11 ALA A  82
GLU A  86
ARG A 206
GLY A  51
HIS A  50
 None
 1.23A 5dxgB-3b89A:
undetectable		 5dxgB-3b89A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 4 ASP A 109
GLY A 113
ASP A 131
ASP A 157
 None
5GP  A 500 ( 4.5A)
5GP  A 500 (-3.1A)
5GP  A 500 (-2.7A)
 0.93A 5e72A-3b89A:
11.7		 5e72A-3b89A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 6 ILE A 124
ILE A 244
LEU A  94
PHE A 203
 None
 0.85A 5vkqA-3b89A:
undetectable
5vkqB-3b89A:
undetectable		 5vkqA-3b89A:
10.12
5vkqB-3b89A:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 6 ILE A 124
ILE A 244
LEU A  94
PHE A 203
 None
 0.82A 5vkqB-3b89A:
undetectable
5vkqC-3b89A:
undetectable		 5vkqB-3b89A:
10.12
5vkqC-3b89A:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 6 ILE A 124
ILE A 244
LEU A  94
PHE A 203
 None
 0.83A 5vkqC-3b89A:
undetectable
5vkqD-3b89A:
undetectable		 5vkqC-3b89A:
10.12
5vkqD-3b89A:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 6 PHE A 203
ILE A 124
ILE A 244
LEU A  94
 None
 0.84A 5vkqA-3b89A:
undetectable
5vkqD-3b89A:
undetectable		 5vkqA-3b89A:
10.12
5vkqD-3b89A:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		5 / 9 ALA A  82
GLU A  86
ARG A 206
GLY A  51
HIS A  50
 None
 1.24A 5wgqA-3b89A:
undetectable		 5wgqA-3b89A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		6 / 12 GLY A 113
ASP A 131
ILE A 132
VAL A 158
LEU A 175
LEU A 179
 5GP  A 500 ( 4.5A)
5GP  A 500 (-3.1A)
5GP  A 500 (-4.1A)
5GP  A 500 (-3.6A)
5GP  A 500 ( 4.7A)
None
 0.92A 5wy0A-3b89A:
13.8		 5wy0A-3b89A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		3 / 3 TYR A  16
ARG A  46
THR A  47
 None
 0.95A 5z84J-3b89A:
undetectable		 5z84J-3b89A:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 3b89 16S RRNA METHYLASE
(Escherichia
coli) 		4 / 8 LEU A  91
LEU A  94
LEU A 114
GLY A 113
 None
None
None
5GP  A 500 ( 4.5A)
 0.90A 6ce2A-3b89A:
undetectable		 6ce2A-3b89A:
21.43