SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b8p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.15A 1l5qA-3b8pA:
undetectable		 1l5qA-3b8pA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.14A 1l5qB-3b8pA:
undetectable		 1l5qB-3b8pA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.13A 1l7xA-3b8pA:
undetectable		 1l7xA-3b8pA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		5 / 11 LEU A 130
LEU A 132
VAL A 134
ILE A  96
ASP A 156
 None
 1.22A 2q6hA-3b8pA:
0.2		 2q6hA-3b8pA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		5 / 11 LEU A 130
LEU A 132
VAL A 134
ILE A  96
ASP A 156
 None
 1.24A 2qeiA-3b8pA:
undetectable		 2qeiA-3b8pA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 5 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.13A 3bcrA-3b8pA:
2.3		 3bcrA-3b8pA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.13A 3dd1A-3b8pA:
undetectable		 3dd1A-3b8pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.14A 3ddsA-3b8pA:
undetectable		 3ddsA-3b8pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.13A 3ddsB-3b8pA:
undetectable		 3ddsB-3b8pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.13A 3ddwA-3b8pA:
undetectable		 3ddwA-3b8pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 6 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.15A 3ddwB-3b8pA:
undetectable		 3ddwB-3b8pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 5 TYR A 151
GLU A 117
LEU A 106
GLN A 113
 None
 1.04A 4qztB-3b8pA:
undetectable		 4qztB-3b8pA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 8 LEU A 167
ASN A  75
ALA A  76
VAL A  79
 None
 0.77A 4zbqA-3b8pA:
undetectable		 4zbqA-3b8pA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3b8p CHAIN LENGTH
DETERMINANT PROTEIN
(Salmonella
enterica) 		4 / 5 GLN A 145
THR A 284
THR A 120
GLY A 143
 None
 1.09A 6gbnC-3b8pA:
undetectable		 6gbnC-3b8pA:
19.14