SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b8y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 9 LEU A 243
ILE A 277
LEU A 266
VAL A 308
LEU A 296
 None
 1.09A 1e7aB-3b8yA:
undetectable		 1e7aB-3b8yA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 ASN A 274
VAL A 273
GLY A 209
TYR A  34
MET A  25
 None
 1.46A 1vidA-3b8yA:
undetectable		 1vidA-3b8yA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 THR A 292
LEU A 266
ILE A 293
VAL A 308
LEU A 226
 None
 1.29A 1wsvA-3b8yA:
undetectable		 1wsvA-3b8yA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 THR A 292
LEU A 266
ILE A 293
VAL A 308
LEU A 226
 None
 1.29A 1wsvB-3b8yA:
undetectable		 1wsvB-3b8yA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 ASN A 274
VAL A 273
GLY A 209
TYR A  34
MET A  25
 None
 1.50A 2cl5B-3b8yA:
0.2		 2cl5B-3b8yA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 9 LEU A 153
ILE A 206
GLY A 209
ILE A 188
ILE A 175
 None
 1.00A 2r5qA-3b8yA:
undetectable		 2r5qA-3b8yA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 9 LEU A 153
ILE A 206
GLY A 209
ILE A 188
ILE A 175
 None
 1.01A 2r5qC-3b8yA:
undetectable		 2r5qC-3b8yA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		6 / 12 VAL A 132
GLY A 136
ALA A 125
PHE A 127
VAL A 161
SER A 119
 None
 1.44A 2v0zO-3b8yA:
undetectable		 2v0zO-3b8yA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 8 VAL A 225
VAL A 268
LEU A 296
VAL A 237
 None
 0.88A 2zujA-3b8yA:
undetectable		 2zujA-3b8yA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 5 VAL A 237
VAL A 268
THR A 242
THR A 235
 None
 1.27A 3bjwD-3b8yA:
undetectable		 3bjwD-3b8yA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 9 LEU A 153
ILE A 206
GLY A 209
ILE A 188
ILE A 175
 None
 1.12A 3d1yB-3b8yA:
undetectable		 3d1yB-3b8yA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 8 ASP A 133
ASP A  89
ASN A 163
GLU A 185
 None
 1.03A 4feuD-3b8yA:
undetectable		 4feuD-3b8yA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 ASP A 133
LEU A 153
ILE A 184
ASN A 163
VAL A 187
 None
 1.14A 4fr0A-3b8yA:
undetectable		 4fr0A-3b8yA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 7 GLU A  61
THR A  53
GLY A  52
THR A  54
 None
 0.85A 4qwpB-3b8yA:
undetectable		 4qwpB-3b8yA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 ASN A 274
VAL A 273
GLY A 209
TYR A  34
MET A  25
 None
 1.45A 5fhrA-3b8yA:
undetectable		 5fhrA-3b8yA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 LEU A 153
ILE A 206
GLY A 209
ILE A 188
ILE A 175
 None
 0.99A 5kqyA-3b8yA:
undetectable		 5kqyA-3b8yA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 9 LEU A 153
ILE A 206
GLY A 209
ILE A 188
ILE A 175
 None
 1.12A 5kr2D-3b8yA:
undetectable		 5kr2D-3b8yA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 7 ASP A 173
GLY A 174
HIS A 176
ASP A 195
 None
None
None
ADA  A 903 (-3.0A)
 1.00A 5nnwD-3b8yA:
undetectable		 5nnwD-3b8yA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 7 ASP A 173
GLY A 174
HIS A 176
ASP A 195
 None
None
None
ADA  A 903 (-3.0A)
 1.07A 5no9D-3b8yA:
undetectable		 5no9D-3b8yA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.64A 5qgjA-3b8yA:
undetectable		 5qgjA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.60A 5qgmA-3b8yA:
undetectable		 5qgmA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.65A 5qgnA-3b8yA:
undetectable		 5qgnA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.70A 5qguA-3b8yA:
undetectable		 5qguA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.67A 5qgvA-3b8yA:
undetectable		 5qgvA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.68A 5qgwA-3b8yA:
undetectable		 5qgwA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.68A 5qgxA-3b8yA:
undetectable		 5qgxA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.67A 5qgyA-3b8yA:
undetectable		 5qgyA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.67A 5qgzA-3b8yA:
undetectable		 5qgzA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.68A 5qh1A-3b8yA:
undetectable		 5qh1A-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.67A 5qh3A-3b8yA:
undetectable		 5qh3A-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.67A 5qh4A-3b8yA:
undetectable		 5qh4A-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.63A 5qh5A-3b8yA:
undetectable		 5qh5A-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.64A 5qh6A-3b8yA:
undetectable		 5qh6A-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.66A 5qh7A-3b8yA:
undetectable		 5qh7A-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.65A 5qh9A-3b8yA:
undetectable		 5qh9A-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.69A 5qhcA-3b8yA:
undetectable		 5qhcA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.68A 5qheA-3b8yA:
undetectable		 5qheA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.65A 5qhfA-3b8yA:
undetectable		 5qhfA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.64A 5qhgA-3b8yA:
undetectable		 5qhgA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		3 / 3 VAL A  90
VAL A  98
GLN A  21
 None
 0.67A 5qhhA-3b8yA:
undetectable		 5qhhA-3b8yA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3b8y ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 5 ASP A 223
PRO A 306
GLU A 310
ARG A 252
 None
None
None
ADA  A 901 ( 3.7A)
 1.36A 5uxcA-3b8yA:
undetectable		 5uxcA-3b8yA:
20.79