SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b8z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.90A 1dhiA-3b8zA:
undetectable		 1dhiA-3b8zA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 11 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.86A 1dhiB-3b8zA:
undetectable		 1dhiB-3b8zA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.91A 1dhjA-3b8zA:
undetectable		 1dhjA-3b8zA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.91A 1dhjB-3b8zA:
undetectable		 1dhjB-3b8zA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.88A 1draA-3b8zA:
undetectable		 1draA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.85A 1draB-3b8zA:
undetectable		 1draB-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.91A 1drbA-3b8zA:
undetectable		 1drbA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.90A 1drbB-3b8zA:
undetectable		 1drbB-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 6 LEU A 328
TRP A 344
PHE A 341
TYR A 359
VAL A 396
 None
 1.49A 1ibgH-3b8zA:
undetectable		 1ibgH-3b8zA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 5 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.16A 1os2A-3b8zA:
10.5		 1os2A-3b8zA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.13A 1os2D-3b8zA:
10.5		 1os2D-3b8zA:
23.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		6 / 10 THR A 378
THR A 407
HIS A 410
GLU A 411
HIS A 414
HIS A 420
 294  A 801 ( 3.8A)
294  A 801 ( 3.8A)
ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.33A 1r55A-3b8zA:
25.7		 1r55A-3b8zA:
30.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.87A 1ra2A-3b8zA:
undetectable		 1ra2A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.93A 1ra3A-3b8zA:
undetectable		 1ra3A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.87A 1ra8A-3b8zA:
undetectable		 1ra8A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.86A 1rb2A-3b8zA:
undetectable		 1rb2A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 1.02A 1rb3B-3b8zA:
undetectable		 1rb3B-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.88A 1rd7A-3b8zA:
undetectable		 1rd7A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.92A 1rd7B-3b8zA:
undetectable		 1rd7B-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.80A 1re7B-3b8zA:
undetectable		 1re7B-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.94A 1rx2A-3b8zA:
undetectable		 1rx2A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.97A 1rx7A-3b8zA:
undetectable		 1rx7A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.22A 1uttA-3b8zA:
10.9		 1uttA-3b8zA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.20A 1utzA-3b8zA:
10.6		 1utzA-3b8zA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.19A 1utzB-3b8zA:
10.7		 1utzB-3b8zA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 1v55A-3b8zA:
undetectable		 1v55A-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 1v55N-3b8zA:
undetectable		 1v55N-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 6 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.11A 1y93A-3b8zA:
10.7		 1y93A-3b8zA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.84A 2d0kA-3b8zA:
undetectable		 2d0kA-3b8zA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.82A 2d0kB-3b8zA:
undetectable		 2d0kB-3b8zA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.89A 2drcA-3b8zA:
undetectable		 2drcA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.86A 2drcB-3b8zA:
undetectable		 2drcB-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 2dyrA-3b8zA:
undetectable		 2dyrA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 2dysA-3b8zA:
undetectable		 2dysA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.73A 2eijA-3b8zA:
undetectable		 2eijA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 2eijN-3b8zA:
undetectable		 2eijN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.77A 2eikN-3b8zA:
undetectable		 2eikN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 2eilN-3b8zA:
undetectable		 2eilN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 2eimA-3b8zA:
undetectable		 2eimA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 2eimN-3b8zA:
undetectable		 2eimN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.73A 2einA-3b8zA:
undetectable		 2einA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.70A 2einN-3b8zA:
undetectable		 2einN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.14A 2hu6A-3b8zA:
10.7		 2hu6A-3b8zA:
23.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_A_097A1001_1
(ADAMTS-1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		7 / 9 ASP A 377
LEU A 379
THR A 407
HIS A 410
GLU A 411
HIS A 414
HIS A 420
 None
294  A 801 (-4.8A)
294  A 801 ( 3.8A)
ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.34A 2jihA-3b8zA:
35.5		 2jihA-3b8zA:
58.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_A_097A1001_1
(ADAMTS-1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		7 / 9 LEU A 379
THR A 407
HIS A 410
GLU A 411
HIS A 414
HIS A 420
LEU A 443
 294  A 801 (-4.8A)
294  A 801 ( 3.8A)
ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
294  A 801 (-4.1A)
 0.64A 2jihA-3b8zA:
35.5		 2jihA-3b8zA:
58.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_B_097B1001_1
(ADAMTS-1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		7 / 8 ASP A 377
LEU A 379
THR A 407
HIS A 410
GLU A 411
HIS A 414
HIS A 420
 None
294  A 801 (-4.8A)
294  A 801 ( 3.8A)
ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.44A 2jihB-3b8zA:
35.6		 2jihB-3b8zA:
58.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_B_097B1001_1
(ADAMTS-1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 8 THR A 407
GLU A 411
HIS A 414
HIS A 420
LEU A 443
 294  A 801 ( 3.8A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
294  A 801 (-4.1A)
 0.94A 2jihB-3b8zA:
35.6		 2jihB-3b8zA:
58.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 6 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.20A 2ow9A-3b8zA:
10.3		 2ow9A-3b8zA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.21A 2ow9B-3b8zA:
10.2		 2ow9B-3b8zA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.25A 2ozrC-3b8zA:
9.8		 2ozrC-3b8zA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.30A 2ozrD-3b8zA:
10.0		 2ozrD-3b8zA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.37A 2ozrE-3b8zA:
10.1		 2ozrE-3b8zA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 410
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.32A 2ozrF-3b8zA:
10.1		 2ozrF-3b8zA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.73A 3abkN-3b8zA:
undetectable		 3abkN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.77A 3ablA-3b8zA:
undetectable		 3ablA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.73A 3ag1A-3b8zA:
undetectable		 3ag1A-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 3ag1N-3b8zA:
undetectable		 3ag1N-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 3ag2N-3b8zA:
undetectable		 3ag2N-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 3ag3A-3b8zA:
undetectable		 3ag3A-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 3ag3N-3b8zA:
undetectable		 3ag3N-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 3asnN-3b8zA:
undetectable		 3asnN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 3asoN-3b8zA:
undetectable		 3asoN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 3bvdA-3b8zA:
undetectable		 3bvdA-3b8zA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.88A 3drcA-3b8zA:
undetectable		 3drcA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.86A 3drcB-3b8zA:
undetectable		 3drcB-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 3dtuC-3b8zA:
undetectable		 3dtuC-3b8zA:
16.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		8 / 9 ASP A 377
LEU A 379
THR A 407
HIS A 410
GLU A 411
HIS A 414
HIS A 420
ILE A 442
 None
294  A 801 (-4.8A)
294  A 801 ( 3.8A)
ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
None
 0.52A 3hy7A-3b8zA:
41.6		 3hy7A-3b8zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		7 / 9 LEU A 379
THR A 407
HIS A 410
GLU A 411
HIS A 414
ILE A 442
LEU A 443
 294  A 801 (-4.8A)
294  A 801 ( 3.8A)
ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
None
294  A 801 (-4.1A)
 0.91A 3hy7A-3b8zA:
41.6		 3hy7A-3b8zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		8 / 9 ASP A 377
LEU A 379
THR A 407
HIS A 410
GLU A 411
HIS A 414
HIS A 420
ILE A 442
 None
294  A 801 (-4.8A)
294  A 801 ( 3.8A)
ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
None
 0.49A 3hy7B-3b8zA:
38.4		 3hy7B-3b8zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		8 / 9 LEU A 379
THR A 407
HIS A 410
GLU A 411
HIS A 414
HIS A 420
ILE A 442
LEU A 443
 294  A 801 (-4.8A)
294  A 801 ( 3.8A)
ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
None
294  A 801 (-4.1A)
 0.87A 3hy7B-3b8zA:
38.4		 3hy7B-3b8zA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 5 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.23A 3kecA-3b8zA:
10.3		 3kecA-3b8zA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 410
GLU A 411
HIS A 414
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
 0.13A 3kecB-3b8zA:
10.3		 3kecB-3b8zA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 5 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.13A 3likA-3b8zA:
10.7		 3likA-3b8zA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.15A 3lilA-3b8zA:
10.8		 3lilA-3b8zA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 5 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.13A 3ljgA-3b8zA:
10.9		 3ljgA-3b8zA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 5 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.17A 3lkaA-3b8zA:
10.7		 3lkaA-3b8zA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.77A 3s33A-3b8zA:
undetectable		 3s33A-3b8zA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 3s38A-3b8zA:
undetectable		 3s38A-3b8zA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.77A 3s39A-3b8zA:
undetectable		 3s39A-3b8zA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.78A 3s3aA-3b8zA:
undetectable		 3s3aA-3b8zA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.80A 3s3bA-3b8zA:
undetectable		 3s3bA-3b8zA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.79A 3s3cA-3b8zA:
undetectable		 3s3cA-3b8zA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 3s3dA-3b8zA:
undetectable		 3s3dA-3b8zA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 6 LEU A 438
HIS A 410
MET A 439
THR A 456
 None
ZN  A 901 ( 3.2A)
None
None
 1.32A 3thrB-3b8zA:
undetectable		 3thrB-3b8zA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.92A 3tq9A-3b8zA:
undetectable		 3tq9A-3b8zA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 11 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.86A 3tqbA-3b8zA:
undetectable		 3tqbA-3b8zA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 10 ILE A 363
ASN A 299
TYR A 302
ILE A 412
ALA A 361
 None
 1.30A 3u6tA-3b8zA:
undetectable		 3u6tA-3b8zA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 3wg7A-3b8zA:
undetectable		 3wg7A-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 3x2qA-3b8zA:
undetectable		 3x2qA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.72A 3x2qN-3b8zA:
undetectable		 3x2qN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 6 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.30A 4a7bA-3b8zA:
10.0		 4a7bA-3b8zA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.86A 4dfrB-3b8zA:
undetectable		 4dfrB-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.88A 4ej1A-3b8zA:
undetectable		 4ej1A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.88A 4fhbA-3b8zA:
undetectable		 4fhbA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.89A 4i13A-3b8zA:
undetectable		 4i13A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.89A 4nx6A-3b8zA:
undetectable		 4nx6A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.90A 4nx7A-3b8zA:
undetectable		 4nx7A-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.90A 4p3rA-3b8zA:
undetectable		 4p3rA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.87A 4pssA-3b8zA:
undetectable		 4pssA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.92A 4pstA-3b8zA:
undetectable		 4pstA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.87A 4x5gB-3b8zA:
undetectable		 4x5gB-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 5b1aA-3b8zA:
undetectable		 5b1aA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.77A 5b1aN-3b8zA:
undetectable		 5b1aN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.72A 5b1bA-3b8zA:
undetectable		 5b1bA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 5b1bN-3b8zA:
undetectable		 5b1bN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 5b3sA-3b8zA:
undetectable		 5b3sA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 5b3sN-3b8zA:
undetectable		 5b3sN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.87A 5eajA-3b8zA:
undetectable		 5eajA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 8 GLY A 380
GLU A 411
ASP A 383
ARG A 392
 294  A 801 (-3.5A)
294  A 801 (-2.7A)
None
None
 1.02A 5gqbA-3b8zA:
undetectable		 5gqbA-3b8zA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.73A 5iy5A-3b8zA:
undetectable		 5iy5A-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 5iy5N-3b8zA:
undetectable		 5iy5N-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 4 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.15A 5n5jA-3b8zA:
10.8		 5n5jA-3b8zA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		4 / 5 HIS A 410
GLU A 411
HIS A 414
HIS A 420
 ZN  A 901 ( 3.2A)
294  A 801 (-2.7A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
 0.14A 5n5kA-3b8zA:
10.9		 5n5kA-3b8zA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.50A 5qgjA-3b8zA:
undetectable		 5qgjA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.49A 5qglA-3b8zA:
undetectable		 5qglA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.52A 5qgmA-3b8zA:
undetectable		 5qgmA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.53A 5qgnA-3b8zA:
undetectable		 5qgnA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.52A 5qguA-3b8zA:
undetectable		 5qguA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.55A 5qgvA-3b8zA:
undetectable		 5qgvA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.56A 5qgwA-3b8zA:
undetectable		 5qgwA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.56A 5qgxA-3b8zA:
undetectable		 5qgxA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.56A 5qgyA-3b8zA:
undetectable		 5qgyA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.56A 5qgzA-3b8zA:
undetectable		 5qgzA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.54A 5qh0A-3b8zA:
undetectable		 5qh0A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.57A 5qh1A-3b8zA:
undetectable		 5qh1A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.57A 5qh2A-3b8zA:
undetectable		 5qh2A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.56A 5qh3A-3b8zA:
undetectable		 5qh3A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.53A 5qh4A-3b8zA:
undetectable		 5qh4A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.55A 5qh5A-3b8zA:
undetectable		 5qh5A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.55A 5qh6A-3b8zA:
undetectable		 5qh6A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.54A 5qh7A-3b8zA:
undetectable		 5qh7A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.53A 5qh9A-3b8zA:
undetectable		 5qh9A-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.55A 5qhaA-3b8zA:
undetectable		 5qhaA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.51A 5qhcA-3b8zA:
undetectable		 5qhcA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.54A 5qheA-3b8zA:
undetectable		 5qheA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.55A 5qhfA-3b8zA:
undetectable		 5qhfA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.53A 5qhgA-3b8zA:
undetectable		 5qhgA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 VAL A 319
VAL A 274
GLN A 345
 None
 0.54A 5qhhA-3b8zA:
undetectable		 5qhhA-3b8zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.88A 5ujxA-3b8zA:
undetectable		 5ujxA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 LEU A 271
PHE A 341
ALA A 275
ALA A 404
GLY A 380
 None
None
None
None
294  A 801 (-3.5A)
 1.02A 5veuA-3b8zA:
undetectable		 5veuA-3b8zA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 LEU A 271
PHE A 341
ALA A 275
ALA A 404
GLY A 380
 None
None
None
None
294  A 801 (-3.5A)
 1.04A 5veuB-3b8zA:
undetectable		 5veuB-3b8zA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.71A 5w97a-3b8zA:
undetectable		 5w97a-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 5waua-3b8zA:
undetectable		 5waua-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.73A 5x19A-3b8zA:
undetectable		 5x19A-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.69A 5x19N-3b8zA:
undetectable		 5x19N-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.70A 5x1bA-3b8zA:
undetectable		 5x1bA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.67A 5x1bN-3b8zA:
undetectable		 5x1bN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.72A 5x1fA-3b8zA:
undetectable		 5x1fA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.64A 5x1fN-3b8zA:
undetectable		 5x1fN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 5xdqN-3b8zA:
undetectable		 5xdqN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.73A 5xdxA-3b8zA:
undetectable		 5xdxA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.72A 5xdxN-3b8zA:
undetectable		 5xdxN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.88A 5z6jA-3b8zA:
undetectable		 5z6jA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		5 / 12 ALA A 298
LEU A 271
ILE A 387
LEU A 472
ILE A 311
 None
 0.92A 5z6kA-3b8zA:
undetectable		 5z6kA-3b8zA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.78A 5z84N-3b8zA:
undetectable		 5z84N-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.77A 5z85N-3b8zA:
undetectable		 5z85N-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.77A 5zcoA-3b8zA:
undetectable		 5zcoA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.74A 5zcoN-3b8zA:
undetectable		 5zcoN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.79A 5zcpN-3b8zA:
undetectable		 5zcpN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 6giqa-3b8zA:
undetectable		 6giqa-3b8zA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.73A 6hu9a-3b8zA:
undetectable		 6hu9a-3b8zA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 6hu9m-3b8zA:
undetectable		 6hu9m-3b8zA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.76A 6nknN-3b8zA:
undetectable		 6nknN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.70A 6nmfA-3b8zA:
undetectable		 6nmfA-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.70A 6nmfN-3b8zA:
undetectable		 6nmfN-3b8zA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b8z PROTEIN ADAMTS-5
(Homo
sapiens) 		3 / 3 HIS A 420
HIS A 414
HIS A 410
 ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.3A)
ZN  A 901 ( 3.2A)
 0.75A 6nmpN-3b8zA:
undetectable		 6nmpN-3b8zA:
16.50