SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b90'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 9 LEU A 243
ILE A 277
LEU A 266
VAL A 308
LEU A 296
 None
 1.12A 1e7aB-3b90A:
undetectable		 1e7aB-3b90A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 8 ALA A 271
LEU A 344
HIS A 247
LEU A 250
 None
 0.95A 1ereE-3b90A:
undetectable		 1ereE-3b90A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 8 ALA A 271
LEU A 344
HIS A 247
LEU A 250
 None
 0.94A 1ereF-3b90A:
undetectable		 1ereF-3b90A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 THR A 292
LEU A 266
ILE A 293
VAL A 308
LEU A 226
 None
 1.30A 1wsvA-3b90A:
undetectable		 1wsvA-3b90A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 THR A 292
LEU A 266
ILE A 293
VAL A 308
LEU A 226
 None
 1.30A 1wsvB-3b90A:
undetectable		 1wsvB-3b90A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 8 ILE A 139
ILE A 155
ILE A 166
VAL A 132
ALA A 159
 None
ZN  A 712 ( 4.8A)
None
None
None
 1.42A 2nniA-3b90A:
undetectable		 2nniA-3b90A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 9 LEU A 153
ILE A 206
GLY A 209
ILE A 188
ILE A 175
 None
 1.12A 2r5qA-3b90A:
undetectable		 2r5qA-3b90A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 9 LEU A 153
ILE A 206
GLY A 209
ILE A 188
ILE A 175
 None
 1.12A 2r5qC-3b90A:
undetectable		 2r5qC-3b90A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 5 VAL A 237
VAL A 268
THR A 242
THR A 235
 None
 1.26A 3bjwG-3b90A:
undetectable		 3bjwG-3b90A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 5 VAL A 237
VAL A 268
THR A 242
THR A 235
 None
 1.24A 3bjwD-3b90A:
undetectable		 3bjwD-3b90A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		4 / 5 ASN A 213
ALA A 197
LEU A 153
GLY A 171
 CA  A 701 (-3.0A)
None
None
None
 0.96A 3dl9A-3b90A:
undetectable		 3dl9A-3b90A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 ASP A 133
LEU A 153
ILE A 184
ASN A 163
VAL A 187
 None
 1.13A 4fr0A-3b90A:
undetectable		 4fr0A-3b90A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 3b90 ENDO-PECTATE LYASE
(Dickeya
chrysanthemi) 		5 / 12 ALA A 197
LEU A 153
ILE A 139
VAL A 161
PHE A 127
 None
 1.26A 5vlmG-3b90A:
undetectable		 5vlmG-3b90A:
20.92