SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b95'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		3 / 3 LEU A 814
HIS A 813
LYS A 817
 None
 1.07A 1y7iA-3b95A:
undetectable		 1y7iA-3b95A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		4 / 7 ILE A 847
LEU A 894
ASN A 876
ASP A 872
 None
 0.81A 1yc2E-3b95A:
undetectable		 1yc2E-3b95A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		4 / 7 ASP A 839
TRP A 848
LEU A 814
GLU A 784
 None
 1.11A 2cdqB-3b95A:
undetectable		 2cdqB-3b95A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		5 / 12 LEU A 894
ALA A 882
THR A 850
ASN A 876
ILE A 847
 None
 1.20A 3a3bA-3b95A:
undetectable		 3a3bA-3b95A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		4 / 7 ASP A 774
SER A 772
GLU A 751
HIS A 747
 None
 1.26A 4aq7A-3b95A:
undetectable		 4aq7A-3b95A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		4 / 8 LEU A 860
LEU A 812
HIS A 813
ILE A 847
 None
 0.98A 4ok1A-3b95A:
undetectable		 4ok1A-3b95A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		3 / 3 ASP A 872
GLY A 841
ASP A 839
 None
 0.51A 4xdtA-3b95A:
undetectable		 4xdtA-3b95A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		4 / 7 LEU A 879
ALA A 883
LEU A 895
ALA A 891
 None
 0.66A 4z90F-3b95A:
undetectable
4z90G-3b95A:
undetectable
4z90H-3b95A:
undetectable
4z90J-3b95A:
undetectable		 4z90F-3b95A:
19.35
4z90G-3b95A:
19.35
4z90H-3b95A:
19.35
4z90J-3b95A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		5 / 12 LEU A 828
LEU A 812
ILE A 795
ALA A 783
LEU A 788
 None
 1.12A 5og9B-3b95A:
undetectable		 5og9B-3b95A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		3 / 3 PHE A 884
ASP A 909
LEU A 928
 None
 0.81A 5uhbC-3b95A:
undetectable		 5uhbC-3b95A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		5 / 9 HIS A 907
ASP A 909
LEU A 945
VAL A 954
SER A 952
 None
 1.27A 6c2mB-3b95A:
undetectable		 6c2mB-3b95A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1
(Homo
sapiens) 		5 / 9 HIS A 907
ASP A 909
LEU A 945
VAL A 954
SER A 952
 None
 1.33A 6c2mD-3b95A:
undetectable		 6c2mD-3b95A:
15.02