SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b9i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3b9i GITR LIGAND
(Mus
musculus) 		4 / 8 TYR A 136
ILE A  91
GLY A 133
LEU A 130
 None
 0.84A 2vctA-3b9iA:
undetectable		 2vctA-3b9iA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3b9i GITR LIGAND
(Mus
musculus) 		4 / 8 TYR A 136
ILE A  91
GLY A 133
LEU A 130
 None
 0.81A 2vctB-3b9iA:
undetectable		 2vctB-3b9iA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3b9i GITR LIGAND
(Mus
musculus) 		4 / 8 TYR A 136
ILE A  91
GLY A 133
LEU A 130
 None
 0.82A 2vctC-3b9iA:
undetectable		 2vctC-3b9iA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3b9i GITR LIGAND
(Mus
musculus) 		4 / 7 TYR A 136
ILE A  91
GLY A 133
LEU A 130
 None
 0.81A 2vctD-3b9iA:
undetectable		 2vctD-3b9iA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 3b9i GITR LIGAND
(Mus
musculus) 		3 / 3 TRP A 161
TRP A  63
THR A  76
 None
 1.48A 4bboB-3b9iA:
undetectable		 4bboB-3b9iA:
21.32