SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		6 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
None
 1.17A 1jffB-3b9jB:
undetectable		 1jffB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 9 LEU B 452
ALA B 466
GLY B 437
LEU B 490
PHE B 516
 None
 1.10A 1nr6A-3b9jB:
undetectable		 1nr6A-3b9jB:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		4 / 8 SER B 368
PHE B 365
LEU B 348
LEU B 334
 None
 1.03A 2bfpA-3b9jB:
undetectable		 2bfpA-3b9jB:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		4 / 8 SER B 368
PHE B 365
LEU B 348
LEU B 334
 None
 1.01A 2bfpD-3b9jB:
undetectable		 2bfpD-3b9jB:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		6 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
None
 1.17A 2hxfB-3b9jB:
undetectable		 2hxfB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		6 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
None
 1.17A 2hxhB-3b9jB:
undetectable		 2hxhB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		6 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
None
 1.17A 2p4nB-3b9jB:
undetectable		 2p4nB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU B 312
VAL B 330
ILE B 407
LEU B 348
PHE B 365
 None
 1.23A 2qk8A-3b9jB:
undetectable		 2qk8A-3b9jB:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		6 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
None
 1.17A 2wbeB-3b9jB:
undetectable		 2wbeB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU B 372
ILE B 409
ILE B 407
PHE B 365
PHE B 390
 None
 1.02A 2ygqA-3b9jB:
undetectable		 2ygqA-3b9jB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU B 372
ILE B 409
LEU B 312
ILE B 407
PHE B 365
 None
 1.03A 2ygqA-3b9jB:
undetectable		 2ygqA-3b9jB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		4 / 5 LEU B 454
GLN B 473
THR B 470
LEU B 513
 None
 1.17A 3ce6D-3b9jB:
undetectable		 3ce6D-3b9jB:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		6 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
None
 1.17A 3dcoB-3b9jB:
undetectable		 3dcoB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		6 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
None
 1.18A 3edlB-3b9jB:
undetectable		 3edlB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 10 ILE B 407
ILE B 409
VAL B 326
GLY B 329
LEU B 305
 None
 1.23A 3em0A-3b9jB:
1.4		 3em0A-3b9jB:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU B 312
VAL B 330
ILE B 407
LEU B 348
PHE B 365
 None
 1.13A 3fl9B-3b9jB:
undetectable		 3fl9B-3b9jB:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 11 LEU B 312
VAL B 330
ILE B 407
LEU B 348
PHE B 365
 None
 1.20A 3fl9C-3b9jB:
undetectable		 3fl9C-3b9jB:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		6 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
None
 1.17A 3iz0B-3b9jB:
undetectable		 3iz0B-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 VAL B 330
LEU B 404
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
 1.29A 3j6pB-3b9jB:
undetectable		 3j6pB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 10 LEU B 312
VAL B 330
ILE B 407
LEU B 348
PHE B 365
 None
 1.12A 3jw5B-3b9jB:
undetectable		 3jw5B-3b9jB:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 10 SER B 240
ILE B 279
GLU B 244
LEU B 248
ASP B 247
 None
 1.35A 3m0wC-3b9jB:
undetectable
3m0wD-3b9jB:
undetectable
3m0wE-3b9jB:
undetectable
3m0wF-3b9jB:
undetectable		 3m0wC-3b9jB:
16.42
3m0wD-3b9jB:
16.42
3m0wE-3b9jB:
16.42
3m0wF-3b9jB:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		4 / 5 ARG B 328
THR B 321
GLU B 414
GLU B 325
 None
 1.41A 3ny4A-3b9jB:
undetectable		 3ny4A-3b9jB:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		4 / 6 VAL B 330
LEU B 334
LEU B 348
PHE B 390
 None
 0.93A 4o1zA-3b9jB:
undetectable		 4o1zA-3b9jB:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 LEU B 348
ALA B 304
PHE B 299
LEU B 312
ILE B 297
 None
 0.96A 4pssA-3b9jB:
undetectable		 4pssA-3b9jB:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		4 / 7 GLY B 458
GLY B 502
TYR B 393
ALA B 460
 None
 0.89A 5e26C-3b9jB:
undetectable
5e26D-3b9jB:
undetectable		 5e26C-3b9jB:
23.13
5e26D-3b9jB:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
 None
FAD  B 606 (-4.6A)
None
None
None
 0.95A 5hnwB-3b9jB:
undetectable		 5hnwB-3b9jB:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
PRO B 410
 None
FAD  B 606 (-4.6A)
None
None
None
 1.02A 5hnyB-3b9jB:
undetectable		 5hnyB-3b9jB:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 VAL B 330
LEU B 404
THR B 373
PRO B 410
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
 1.23A 5ogcB-3b9jB:
undetectable		 5ogcB-3b9jB:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 THR B 354
LEU B 305
PHE B 390
PHE B 365
VAL B 364
 FAD  B 606 (-4.5A)
None
None
None
None
 1.20A 6a94B-3b9jB:
undetectable		 6a94B-3b9jB:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		5 / 12 VAL B 330
LEU B 404
LEU B 372
THR B 373
GLY B 296
 None
FAD  B 606 (-4.6A)
None
None
None
 0.91A 6b0cD-3b9jB:
undetectable		 6b0cD-3b9jB:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3b9j XANTHINE OXIDASE
(Bos
taurus) 		3 / 3 LEU B 257
GLY B 350
PHE B 389
 FAD  B 606 (-4.3A)
FAD  B 606 (-3.5A)
None
 0.67A 6exiC-3b9jB:
undetectable		 6exiC-3b9jB:
14.52