SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 3b9k FAB HEAVY CHAIN
(Rattus
rattus) 		5 / 12 ARG H  66
PRO H  41
LEU H  20
LEU H  18
ASP H  86
 None
 1.28A 1e7wA-3b9kH:
undetectable		 1e7wA-3b9kH:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3b9k FAB HEAVY CHAIN
(Rattus
rattus) 		4 / 6 SER H  28
GLY H  55
THR H  73
ILE H  51
 None
 0.84A 1gtnD-3b9kH:
1.5
1gtnE-3b9kH:
1.4		 1gtnD-3b9kH:
16.67
1gtnE-3b9kH:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 3b9k FAB HEAVY CHAIN
(Rattus
rattus) 		4 / 7 LEU H  82
MET H  82
LEU H  80
MET H  48
 None
 1.05A 1linA-3b9kH:
undetectable		 1linA-3b9kH:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3b9k FAB HEAVY CHAIN
(Rattus
rattus) 		3 / 3 THR H 110
GLU H 150
HIS H 212
 None
 0.79A 3g1uB-3b9kH:
undetectable		 3g1uB-3b9kH:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3b9k FAB HEAVY CHAIN
(Rattus
rattus) 		5 / 10 ILE H  51
GLY H  50
GLY H  49
PHE H  79
SER H  19
 None
 0.96A 4fakA-3b9kH:
undetectable		 4fakA-3b9kH:
19.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M93_B_ACTB305_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN)		 3b9k FAB HEAVY CHAIN
(Rattus
rattus) 		4 / 4 SER H  19
THR H  21
PHE H  79
LYS H  81
 None
 0.41A 4m93B-3b9kH:
25.0		 4m93B-3b9kH:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3b9k FAB HEAVY CHAIN
(Rattus
rattus) 		3 / 3 SER H 216
ALA H 211
VAL H 210
 None
 0.68A 4o2bC-3b9kH:
undetectable		 4o2bC-3b9kH:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3b9k FAB HEAVY CHAIN
(Rattus
rattus) 		5 / 11 VAL H 219
THR H 217
VAL H 223
ALA H 118
VAL H 154
 None
 1.13A 6dryA-3b9kH:
undetectable		 6dryA-3b9kH:
17.69