SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b9n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		3 / 3 ALA A  57
VAL A 103
TRP A 132
 None
 0.71A 1c4dC-3b9nA:
undetectable
1c4dD-3b9nA:
undetectable		 1c4dC-3b9nA:
7.55
1c4dD-3b9nA:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		3 / 3 TRP A 132
ALA A  57
VAL A 103
 None
 0.82A 1c4dC-3b9nA:
undetectable
1c4dD-3b9nA:
undetectable		 1c4dC-3b9nA:
7.55
1c4dD-3b9nA:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		3 / 3 ASN A 133
TYR A 158
SER A 106
 None
 0.61A 2gvcB-3b9nA:
undetectable		 2gvcB-3b9nA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		3 / 3 ASN A 133
TYR A 158
SER A 106
 None
 0.61A 2gvcE-3b9nA:
undetectable		 2gvcE-3b9nA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		3 / 3 ASP A 406
TYR A 407
LYS A  97
 None
 0.88A 2othA-3b9nA:
undetectable		 2othA-3b9nA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 6 ASP A 260
ILE A 261
GLN A 226
TYR A 158
 None
 1.20A 2ya7C-3b9nA:
undetectable		 2ya7C-3b9nA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		3 / 3 HIS A 311
HIS A 308
HIS A  20
 None
 0.85A 3mihA-3b9nA:
undetectable		 3mihA-3b9nA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		5 / 12 LEU A 246
GLY A 371
ALA A 370
ILE A   5
LEU A 254
 None
 0.95A 3ogqB-3b9nA:
undetectable		 3ogqB-3b9nA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		5 / 12 ALA A  53
LEU A  46
VAL A 283
ALA A   9
ASN A   8
 None
 0.98A 3r9cA-3b9nA:
undetectable		 3r9cA-3b9nA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		5 / 10 ASP A 427
PHE A 417
VAL A 223
ILE A 224
ILE A 429
 None
 1.45A 3uf8A-3b9nA:
undetectable		 3uf8A-3b9nA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		5 / 10 ASP A 427
PHE A 417
VAL A 223
ILE A 224
ILE A 429
 None
 1.39A 3uqaA-3b9nA:
undetectable		 3uqaA-3b9nA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		3 / 3 ASN A 376
LEU A 416
PHE A  51
 None
 0.76A 4dajB-3b9nA:
undetectable		 4dajB-3b9nA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 6 PHE A 245
ASN A 133
ALA A 131
LEU A 416
 None
 0.82A 4ejgD-3b9nA:
undetectable		 4ejgD-3b9nA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 5 HIS A 311
HIS A  20
GLN A  79
TYR A  63
 None
 1.34A 4gboA-3b9nA:
undetectable		 4gboA-3b9nA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 9 PHE A 278
HIS A   6
PHE A 417
ILE A 224
 None
 1.32A 4jvlA-3b9nA:
undetectable		 4jvlA-3b9nA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 4 TYR A  66
THR A  72
GLY A 307
LEU A 305
 None
 0.87A 4w5nA-3b9nA:
undetectable		 4w5nA-3b9nA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 6 TYR A 365
ILE A 372
VAL A 251
ALA A 370
 None
 0.78A 5cu6A-3b9nA:
undetectable		 5cu6A-3b9nA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 8 TYR A 205
LYS A 204
THR A 108
ILE A 151
 None
 1.06A 5jhdE-3b9nA:
undetectable
5jhdG-3b9nA:
undetectable		 5jhdE-3b9nA:
20.98
5jhdG-3b9nA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 7 TYR A 365
ILE A 372
VAL A 251
ALA A 370
 None
 0.78A 5osrA-3b9nA:
undetectable		 5osrA-3b9nA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 5 HIS A 311
HIS A  20
GLN A  79
TYR A  63
 None
 1.35A 5uizA-3b9nA:
undetectable		 5uizA-3b9nA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		4 / 6 MET A 341
GLU A 306
GLY A 313
GLY A 317
 None
 0.87A 5x7pB-3b9nA:
undetectable		 5x7pB-3b9nA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 3b9n ALKANE MONOOXYGENASE
(Geobacillus
thermodenitrific
ans) 		5 / 10 GLY A 420
TYR A 422
ASP A 426
GLU A 177
GLU A 173
 None
 1.48A 6cgdA-3b9nA:
0.0		 6cgdA-3b9nA:
10.71