SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		4 / 7 LEU A 552
GLY A 560
ILE A 469
VAL A 466
 None
 0.75A 1p2yA-3b9pA:
undetectable		 1p2yA-3b9pA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		4 / 5 LEU A 679
SER A 730
LEU A 664
LEU A 671
 None
 1.17A 1yajD-3b9pA:
2.7		 1yajD-3b9pA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 567
PHE A 568
ILE A 581
ALA A 549
THR A 553
 None
 0.88A 2v0mC-3b9pA:
undetectable		 2v0mC-3b9pA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 LEU A 567
ILE A 581
ALA A 549
THR A 553
LEU A 602
 None
 1.11A 2v0mD-3b9pA:
undetectable		 2v0mD-3b9pA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 LEU A 625
PHE A 544
LEU A 545
ASP A 582
 None
 1.12A 2wm3A-3b9pA:
undetectable		 2wm3A-3b9pA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 520
ALA A 626
VAL A 624
PHE A 568
LEU A 470
 None
 1.17A 3b0wA-3b9pA:
undetectable		 3b0wA-3b9pA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 520
ALA A 626
VAL A 624
PHE A 568
LEU A 470
 None
 1.17A 3b0wB-3b9pA:
undetectable		 3b0wB-3b9pA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 10 ALA A 542
MET A 574
ILE A 473
LEU A 567
ILE A 579
 None
 1.13A 3hbbA-3b9pA:
undetectable		 3hbbA-3b9pA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 567
ALA A 533
ALA A 549
SER A 551
LEU A 552
 None
 0.86A 3ln1A-3b9pA:
undetectable		 3ln1A-3b9pA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 567
ALA A 533
ALA A 549
SER A 551
LEU A 552
 None
 0.86A 3ln1B-3b9pA:
undetectable		 3ln1B-3b9pA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 567
ALA A 533
ALA A 549
SER A 551
LEU A 552
 None
 0.86A 3ln1C-3b9pA:
undetectable		 3ln1C-3b9pA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 GLU A 705
ARG A 704
ASP A 726
ASP A 697
 None
 1.27A 4kcnB-3b9pA:
undetectable		 4kcnB-3b9pA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 VAL A 499
VAL A 623
ILE A 578
LEU A 532
 None
 0.92A 4l1wB-3b9pA:
undetectable		 4l1wB-3b9pA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 ILE A 473
ALA A 549
SER A 551
LEU A 552
LEU A 563
 None
 0.95A 4o1zA-3b9pA:
undetectable		 4o1zA-3b9pA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b9p CG5977-PA, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 567
ALA A 533
ALA A 549
SER A 551
LEU A 552
 None
 0.83A 5jw1A-3b9pA:
undetectable		 5jw1A-3b9pA:
20.04