SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b9t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.93A 1dz4A-3b9tA:
undetectable
1dz4A-3b9tA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.94A 1dz4B-3b9tA:
undetectable
1dz4B-3b9tA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.97A 1iwiA-3b9tA:
undetectable
1iwiA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 GLY A 468
ILE A 459
TRP A 467
VAL A 463
None
1.14A 1rs7A-3b9tA:
undetectable
1rs7A-3b9tA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.92A 1t85A-3b9tA:
undetectable
1t85A-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.90A 1t86A-3b9tA:
undetectable
1t86A-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.93A 1t87A-3b9tA:
undetectable
1t87A-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.92A 1t87B-3b9tA:
undetectable
1t87B-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.88A 1t88B-3b9tA:
undetectable
1t88B-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 THR A 292
GLU A 350
HIS A 111
None
EDO  A 494 (-3.5A)
None
0.80A 1xwfA-3b9tA:
undetectable
1xwfA-3b9tA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 THR A 292
GLU A 350
HIS A 111
None
EDO  A 494 (-3.5A)
None
0.78A 1xwfB-3b9tA:
undetectable
1xwfB-3b9tA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 THR A 292
GLU A 350
HIS A 111
None
EDO  A 494 (-3.5A)
None
0.78A 1xwfC-3b9tA:
undetectable
1xwfC-3b9tA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 THR A 292
GLU A 350
HIS A 111
None
EDO  A 494 (-3.5A)
None
0.78A 1xwfD-3b9tA:
undetectable
1xwfD-3b9tA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 1yrcA-3b9tA:
undetectable
1yrcA-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 1yrdA-3b9tA:
undetectable
1yrdA-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 PHE A 311
THR A 292
LEU A 162
GLY A  85
None
0.87A 2a1oA-3b9tA:
undetectable
2a1oA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.93A 2cppA-3b9tA:
undetectable
2cppA-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 THR A 361
PRO A  76
TYR A  74
EDO  A 489 (-4.3A)
None
None
0.80A 2dxrA-3b9tA:
undetectable
2dxrA-3b9tA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.90A 2feuA-3b9tA:
undetectable
2feuA-3b9tA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.91A 2feuB-3b9tA:
undetectable
2feuB-3b9tA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.92A 2qblA-3b9tA:
undetectable
2qblA-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 GLY A 164
GLY A 340
PHE A 364
PHE A 366
None
1.03A 2qx6A-3b9tA:
undetectable
2qx6B-3b9tA:
undetectable
2qx6A-3b9tA:
19.86
2qx6B-3b9tA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 PRO A 385
GLY A 312
TYR A 328
None
0.71A 2vouA-3b9tA:
undetectable
2vouA-3b9tA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 PRO A 385
GLY A 312
TYR A 328
None
0.73A 2vouB-3b9tA:
undetectable
2vouB-3b9tA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
6 / 12 SER A 305
GLY A  85
GLY A 340
TRP A  84
THR A 107
LEU A 360
None
1.31A 2wa2B-3b9tA:
undetectable
2wa2B-3b9tA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA6_0
(GRAMICIDIN A)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 ALA A 205
VAL A 224
TRP A 246
TRP A 207
None
None
None
EDO  A 490 (-3.5A)
1.38A 2xdcA-3b9tA:
undetectable
2xdcB-3b9tA:
undetectable
2xdcA-3b9tA:
3.02
2xdcB-3b9tA:
3.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB6_0
(GRAMICIDIN A)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 TRP A 246
TRP A 207
ALA A 205
VAL A 224
None
EDO  A 490 (-3.5A)
None
None
1.40A 2xdcA-3b9tA:
undetectable
2xdcB-3b9tA:
undetectable
2xdcA-3b9tA:
3.02
2xdcB-3b9tA:
3.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 VAL A 339
LEU A 387
GLY A 321
ALA A 324
None
0.75A 2xfsA-3b9tA:
undetectable
2xfsA-3b9tA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 VAL A 339
LEU A 387
GLY A 321
ALA A 324
None
0.77A 2xh9A-3b9tA:
undetectable
2xh9A-3b9tA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA6_0
(VAL-GRAMICIDIN A)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 ALA A 205
VAL A 224
TRP A 246
TRP A 207
None
None
None
EDO  A 490 (-3.5A)
1.39A 2y5mA-3b9tA:
undetectable
2y5mB-3b9tA:
undetectable
2y5mA-3b9tA:
3.02
2y5mB-3b9tA:
3.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA6_0
(VAL-GRAMICIDIN A)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 ALA A 205
VAL A 224
TRP A 246
TRP A 207
None
None
None
EDO  A 490 (-3.5A)
1.39A 2y6nA-3b9tA:
undetectable
2y6nB-3b9tA:
undetectable
2y6nA-3b9tA:
3.02
2y6nB-3b9tA:
3.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB6_0
(VAL-GRAMICIDIN A)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 TRP A 246
TRP A 207
ALA A 205
VAL A 224
None
EDO  A 490 (-3.5A)
None
None
1.40A 2y6nA-3b9tA:
undetectable
2y6nB-3b9tA:
undetectable
2y6nA-3b9tA:
3.02
2y6nB-3b9tA:
3.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.83A 2z97A-3b9tA:
undetectable
2z97A-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.94A 2zawA-3b9tA:
undetectable
2zawA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.88A 2zaxA-3b9tA:
undetectable
2zaxA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.85A 2zuhA-3b9tA:
undetectable
2zuhA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.88A 2zuiA-3b9tA:
undetectable
2zuiA-3b9tA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 2zujA-3b9tA:
undetectable
2zujA-3b9tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 SER A 305
GLU A 350
ASP A 348
None
EDO  A 494 (-3.5A)
EDO  A 495 (-4.1A)
0.77A 2zulA-3b9tA:
undetectable
2zulA-3b9tA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.88A 2zwtA-3b9tA:
undetectable
2zwtA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.88A 2zwuA-3b9tA:
undetectable
2zwuA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 LYS A 274
ASN A 113
PRO A 263
TRP A  84
EDO  A 496 (-2.7A)
None
None
None
1.49A 3bjwD-3b9tA:
undetectable
3bjwD-3b9tA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 GLY A 156
GLY A  85
GLY A 143
None
0.41A 3bogC-3b9tA:
undetectable
3bogC-3b9tA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 4 GLY A 156
GLY A 154
GLY A 145
GLY A 143
None
0.64A 3bogC-3b9tA:
undetectable
3bogC-3b9tA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 GLY A 156
GLY A  85
GLY A 143
None
0.40A 3bogD-3b9tA:
undetectable
3bogD-3b9tA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 4 GLY A 156
GLY A 154
GLY A 145
GLY A 143
None
0.64A 3bogD-3b9tA:
undetectable
3bogD-3b9tA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
3 / 3 SER A 305
GLU A 350
ASP A 348
None
EDO  A 494 (-3.5A)
EDO  A 495 (-4.1A)
0.80A 3dmhA-3b9tA:
undetectable
3dmhA-3b9tA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.91A 3fwfA-3b9tA:
undetectable
3fwfA-3b9tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 3fwfB-3b9tA:
undetectable
3fwfB-3b9tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.91A 3fwgA-3b9tA:
undetectable
3fwgA-3b9tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.90A 3fwgB-3b9tA:
undetectable
3fwgB-3b9tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.90A 3fwiA-3b9tA:
undetectable
3fwiA-3b9tA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 3fwjA-3b9tA:
undetectable
3fwjA-3b9tA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 4 ARG A 142
ASP A 464
GLY A 291
THR A 109
None
EDO  A 494 ( 3.7A)
MG  A 485 ( 4.2A)
None
1.39A 3k4vB-3b9tA:
undetectable
3k4vB-3b9tA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.90A 3l63A-3b9tA:
undetectable
3l63A-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 3wrhA-3b9tA:
undetectable
3wrhA-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.90A 3wrhE-3b9tA:
undetectable
3wrhE-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 3wrjA-3b9tA:
undetectable
3wrjA-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.91A 3wrjE-3b9tA:
undetectable
3wrjE-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.91A 3wrlA-3b9tA:
undetectable
3wrlA-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.91A 3wrlE-3b9tA:
undetectable
3wrlE-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.88A 3wrmA-3b9tA:
undetectable
3wrmA-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.88A 3wrmF-3b9tA:
undetectable
3wrmF-3b9tA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 HIS A 110
GLU A 357
ASP A 114
SER A 201
EDO  A 494 (-4.0A)
MG  A 484 ( 2.0A)
None
None
1.07A 4apjA-3b9tA:
undetectable
4apjP-3b9tA:
undetectable
4apjA-3b9tA:
20.32
4apjP-3b9tA:
3.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 GLY A 468
ILE A 459
TRP A 467
VAL A 463
None
1.11A 4d33A-3b9tA:
undetectable
4d33A-3b9tA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 GLY A 468
ILE A 459
TRP A 467
VAL A 463
None
1.14A 4d33B-3b9tA:
undetectable
4d33B-3b9tA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 GLY A 468
ILE A 459
TRP A 467
VAL A 463
None
1.14A 4d39B-3b9tA:
undetectable
4d39B-3b9tA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.87A 4ek1A-3b9tA:
undetectable
4ek1A-3b9tA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 4g3rA-3b9tA:
undetectable
4g3rA-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.90A 4g3rB-3b9tA:
undetectable
4g3rB-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 GLY A 340
ARG A 187
PHE A 364
ILE A 105
None
1.00A 4j4vC-3b9tA:
undetectable
4j4vC-3b9tA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.89A 4kkyX-3b9tA:
undetectable
4kkyX-3b9tA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 5 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.87A 4l49A-3b9tA:
undetectable
4l49A-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.87A 4l4aA-3b9tA:
undetectable
4l4aA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.88A 4l4cA-3b9tA:
undetectable
4l4cA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.92A 4l4gA-3b9tA:
undetectable
4l4gA-3b9tA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 TYR A 227
HIS A 160
HIS A 110
ASP A 316
GLY A 291
None
EDO  A 494 ( 3.9A)
EDO  A 494 (-4.0A)
MG  A 485 ( 1.8A)
MG  A 485 ( 4.2A)
1.13A 4qa0A-3b9tA:
undetectable
4qa0A-3b9tA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 11 TYR A 227
HIS A 160
HIS A 110
ASP A 316
GLY A 291
None
EDO  A 494 ( 3.9A)
EDO  A 494 (-4.0A)
MG  A 485 ( 1.8A)
MG  A 485 ( 4.2A)
1.19A 4qa0B-3b9tA:
undetectable
4qa0B-3b9tA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 TYR A 227
HIS A 160
HIS A 110
ASP A 316
GLY A 291
None
EDO  A 494 ( 3.9A)
EDO  A 494 (-4.0A)
MG  A 485 ( 1.8A)
MG  A 485 ( 4.2A)
1.23A 4qa2A-3b9tA:
undetectable
4qa2A-3b9tA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 TYR A 227
HIS A 160
HIS A 110
ASP A 316
GLY A 291
None
EDO  A 494 ( 3.9A)
EDO  A 494 (-4.0A)
MG  A 485 ( 1.8A)
MG  A 485 ( 4.2A)
1.23A 4qa2B-3b9tA:
undetectable
4qa2B-3b9tA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 TRP A  84
SER A 112
GLY A  85
GLY A 291
PRO A 342
None
None
None
MG  A 485 ( 4.2A)
None
1.46A 4uinH-3b9tA:
undetectable
4uinL-3b9tA:
undetectable
4uinH-3b9tA:
19.59
4uinL-3b9tA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 GLY A 340
ASP A 341
HIS A 110
PHE A 130
ALA A  77
None
MG  A 484 (-2.0A)
EDO  A 494 (-4.0A)
None
None
1.19A 4wh5A-3b9tA:
undetectable
4wh5A-3b9tA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 11 ALA A  77
VAL A 184
GLY A 340
PHE A 290
SER A 359
None
1.17A 4xp4A-3b9tA:
undetectable
4xp4A-3b9tA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 10 ASP A 261
HIS A 111
HIS A 110
VAL A 159
THR A 354
None
None
EDO  A 494 (-4.0A)
None
None
1.49A 4yhaB-3b9tA:
undetectable
4yhaB-3b9tA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 SER A 201
HIS A 160
HIS A 110
ASP A 316
GLY A 291
None
EDO  A 494 ( 3.9A)
EDO  A 494 (-4.0A)
MG  A 485 ( 1.8A)
MG  A 485 ( 4.2A)
1.10A 5eenA-3b9tA:
undetectable
5eenA-3b9tA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 ASP A 230
ALA A 231
GLY A 200
SER A 201
TYR A 227
None
1.27A 5hfjE-3b9tA:
undetectable
5hfjE-3b9tA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 GLU A 350
ASP A 341
GLY A 291
LEU A 387
ALA A 324
EDO  A 494 (-3.5A)
MG  A 484 (-2.0A)
MG  A 485 ( 4.2A)
None
None
1.36A 5kbwA-3b9tA:
undetectable
5kbwA-3b9tA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 HIS A 160
ASP A 341
HIS A 110
TRP A 207
EDO  A 494 ( 3.9A)
MG  A 484 (-2.0A)
EDO  A 494 (-4.0A)
EDO  A 490 (-3.5A)
1.43A 5m45A-3b9tA:
0.0
5m45A-3b9tA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 HIS A 160
ASP A 341
HIS A 110
TRP A 207
EDO  A 494 ( 3.9A)
MG  A 484 (-2.0A)
EDO  A 494 (-4.0A)
EDO  A 490 (-3.5A)
1.43A 5m45D-3b9tA:
0.0
5m45D-3b9tA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 HIS A 160
ASP A 341
HIS A 110
TRP A 207
EDO  A 494 ( 3.9A)
MG  A 484 (-2.0A)
EDO  A 494 (-4.0A)
EDO  A 490 (-3.5A)
1.43A 5m45G-3b9tA:
0.0
5m45G-3b9tA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 6 HIS A 160
ASP A 341
HIS A 110
TRP A 207
EDO  A 494 ( 3.9A)
MG  A 484 (-2.0A)
EDO  A 494 (-4.0A)
EDO  A 490 (-3.5A)
1.43A 5m45J-3b9tA:
0.0
5m45J-3b9tA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TRP A 246
VAL A 203
TYR A 244
SER A 201
None
1.25A 5umwA-3b9tA:
undetectable
5umwF-3b9tA:
undetectable
5umwA-3b9tA:
11.28
5umwF-3b9tA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 7 TYR A 227
LEU A 279
VAL A 278
VAL A 223
None
0.92A 5wk9A-3b9tA:
undetectable
5wk9A-3b9tA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 LEU A 295
PRO A 297
SER A 331
GLY A 313
GLY A 294
None
0.99A 5wyqB-3b9tA:
undetectable
5wyqB-3b9tA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
4 / 8 PRO A 342
ALA A 185
THR A 361
ALA A 126
None
EDO  A 489 ( 3.7A)
EDO  A 489 (-4.3A)
None
1.01A 5x2tI-3b9tA:
undetectable
5x2tJ-3b9tA:
undetectable
5x2tK-3b9tA:
undetectable
5x2tL-3b9tA:
undetectable
5x2tI-3b9tA:
16.03
5x2tJ-3b9tA:
20.06
5x2tK-3b9tA:
16.03
5x2tL-3b9tA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus)
5 / 12 ASP A 341
PHE A 290
PHE A 337
PHE A 366
TYR A 328
MG  A 484 (-2.0A)
None
None
None
None
1.49A 6iblA-3b9tA:
undetectable
6iblA-3b9tA:
22.37