SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 3b9v HEAVY CHAIN VARIABLE
DOMAIN
(Homo
sapiens) 		5 / 12 PRO A  41
LEU A 108
LEU A  18
LEU A  82
ASP A  86
 None
 1.26A 1e7wA-3b9vA:
undetectable		 1e7wA-3b9vA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3b9v HEAVY CHAIN VARIABLE
DOMAIN
(Homo
sapiens) 		4 / 5 ILE A  34
PRO A  52
TYR A  52
TYR A  33
 None
 0.81A 3d9lA-3b9vA:
undetectable
3d9lY-3b9vA:
undetectable		 3d9lA-3b9vA:
17.09
3d9lY-3b9vA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 3b9v HEAVY CHAIN VARIABLE
DOMAIN
(Homo
sapiens) 		5 / 9 ARG A  38
ALA A  84
VAL A 111
SER A 112
ASP A  86
 None
 1.46A 6c2mA-3b9vA:
undetectable		 6c2mA-3b9vA:
21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 3b9v HEAVY CHAIN VARIABLE
DOMAIN
(Homo
sapiens) 		3 / 3 TYR A  59
GLY A  65
THR A  68
 None
 0.09A 6cjkB-3b9vA:
20.0		 6cjkB-3b9vA:
61.48