SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bac'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		4 / 8 LEU A 190
ARG A 184
PHE A 182
GLY A 181
 None
 0.75A 1fapB-3bacA:
undetectable		 1fapB-3bacA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		4 / 8 GLU A 300
ILE A  98
PRO A 106
LEU A 109
 None
 0.87A 1hmyA-3bacA:
undetectable		 1hmyA-3bacA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		5 / 12 ILE A  98
GLU A 300
ALA A 242
LEU A 260
ILE A 292
 None
 1.32A 2xkwB-3bacA:
undetectable		 2xkwB-3bacA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		4 / 8 LEU A 169
ILE A 252
ARG A 172
GLY A 173
 None
None
3B9  A 501 ( 4.8A)
None
 0.95A 3b9lA-3bacA:
undetectable		 3b9lA-3bacA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		5 / 12 SER A 207
LEU A 120
VAL A 122
ILE A 150
LEU A 185
 None
 1.22A 3g9eA-3bacA:
undetectable		 3g9eA-3bacA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		5 / 12 LEU A 158
LEU A 131
GLN A 133
VAL A 122
THR A 152
 None
 1.36A 3zqtA-3bacA:
undetectable		 3zqtA-3bacA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		4 / 8 THR A 216
LEU A 211
ASN A 149
ARG A 209
 None
 1.19A 4m5mA-3bacA:
undetectable		 4m5mA-3bacA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		4 / 5 ARG A  74
THR A 141
THR A 142
ASP A 139
 None
 1.49A 4qwpB-3bacA:
undetectable		 4qwpB-3bacA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		4 / 5 GLY A 143
THR A 136
HIS A  75
GLY A 140
 None
 1.16A 4v20A-3bacA:
undetectable		 4v20A-3bacA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		5 / 12 LEU A 208
GLU A 174
VAL A 175
THR A 136
GLU A 144
 None
PO4  A 403 ( 3.3A)
None
None
None
 1.38A 5xipD-3bacA:
undetectable		 5xipD-3bacA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bac DNA LIGASE
(Haemophilus
influenzae) 		3 / 3 ARG A  97
PHE A 303
PHE A  94
 None
3B9  A 501 (-3.8A)
None
 0.98A 6nknC-3bacA:
undetectable
6nknJ-3bacA:
undetectable		 6nknC-3bacA:
22.03
6nknJ-3bacA:
13.26