SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3baz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 9 LEU A 221
ALA A 244
GLY A 251
LEU A 255
LEU A 241
 None
 1.12A 1nr6A-3bazA:
undetectable		 1nr6A-3bazA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 10 GLY A 252
VAL A 226
GLY A 225
ASN A 273
VAL A 115
 None
 1.23A 1pwyE-3bazA:
undetectable		 1pwyE-3bazA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 ALA A 193
ILE A 212
LEU A 221
ALA A 220
CYH A 203
 None
None
None
None
NAP  A 500 (-4.8A)
 0.88A 2aclG-3bazA:
undetectable		 2aclG-3bazA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 GLY A 254
GLY A 252
ASP A 256
ASP A 106
ILE A 109
 None
None
NAP  A 500 (-3.9A)
None
None
 1.07A 2hmyB-3bazA:
4.0		 2hmyB-3bazA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 10 ILE A 149
ILE A 150
LEU A 192
ASN A 195
VAL A 217
 None
 1.24A 2nnhB-3bazA:
undetectable		 2nnhB-3bazA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 9 ALA A 160
ALA A 202
GLY A 151
GLY A 153
ILE A 155
 None
None
NAP  A 500 (-3.5A)
NAP  A 500 (-3.1A)
NAP  A 500 (-3.6A)
 1.20A 2v7bB-3bazA:
4.9		 2v7bB-3bazA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		6 / 12 HIS A 279
GLY A 231
VAL A 104
LEU A 107
ILE A 213
LEU A 255
 NAP  A 500 (-4.1A)
NAP  A 500 (-3.8A)
NAP  A 500 ( 4.7A)
None
None
None
 1.41A 3cjtO-3bazA:
8.2		 3cjtO-3bazA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 GLU A 259
VAL A 201
ASP A 237
ILE A 213
ASN A 214
 None
 1.36A 3jb3A-3bazA:
3.6		 3jb3A-3bazA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 LEU A 241
VAL A 147
ALA A 253
GLY A 252
LEU A 116
 None
 0.94A 3ku1A-3bazA:
6.6		 3ku1A-3bazA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 LEU A 241
VAL A 147
ALA A 253
GLY A 252
LEU A 116
 None
 0.90A 3ku1C-3bazA:
5.1		 3ku1C-3bazA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 LEU A 241
VAL A 147
ALA A 253
GLY A 252
LEU A 116
 None
 0.89A 3ku1G-3bazA:
6.4		 3ku1G-3bazA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 GLY A 156
GLY A 151
VAL A 201
ALA A 108
ALA A 105
 None
NAP  A 500 (-3.5A)
None
None
None
 1.07A 3p2kD-3bazA:
undetectable		 3p2kD-3bazA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 11 VAL A 201
ALA A 202
GLY A 151
ALA A 163
LEU A 227
 None
None
NAP  A 500 (-3.5A)
None
None
 1.21A 3rc0A-3bazA:
undetectable		 3rc0A-3bazA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 3 VAL A 126
GLY A 129
LYS A 132
 None
 0.68A 4k50A-3bazA:
undetectable		 4k50A-3bazA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 3 VAL A 126
GLY A 129
LYS A 132
 None
 0.64A 4k50E-3bazA:
undetectable		 4k50E-3bazA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 3 VAL A 126
GLY A 129
LYS A 132
 None
 0.68A 4k50I-3bazA:
undetectable		 4k50I-3bazA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		4 / 4 GLY A 222
LEU A 116
PHE A 142
ILE A 198
 None
 0.92A 4xv2A-3bazA:
undetectable		 4xv2A-3bazA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 5 GLY A 231
GLY A 233
GLU A 261
 NAP  A 500 (-3.8A)
None
None
 0.51A 4z2eA-3bazA:
undetectable
4z2eD-3bazA:
undetectable		 4z2eA-3bazA:
21.77
4z2eD-3bazA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 PRO A 265
LEU A 268
PHE A 258
ARG A 260
GLY A 233
 None
 1.25A 5k7uA-3bazA:
undetectable		 5k7uA-3bazA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 3 ARG A 117
ILE A 112
PHE A 142
 None
 0.44A 5kirA-3bazA:
undetectable		 5kirA-3bazA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 ALA A  55
GLY A  56
LYS A  80
GLU A  88
GLU A  87
 None
 1.16A 5nwuA-3bazA:
undetectable		 5nwuA-3bazA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 10 SER A 174
GLY A 151
ILE A 170
ALA A 160
LEU A 157
 NAP  A 500 (-2.7A)
NAP  A 500 (-3.5A)
None
None
None
 1.15A 5zjiA-3bazA:
undetectable
5zjiJ-3bazA:
undetectable		 5zjiA-3bazA:
13.33
5zjiJ-3bazA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 GLY A  56
TYR A  29
ALA A  55
ILE A  46
LEU A  65
 None
 1.14A 6b3aA-3bazA:
2.1		 6b3aA-3bazA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 GLY A  56
TYR A  29
ALA A  55
ILE A  46
LEU A  65
 None
 1.13A 6b3bA-3bazA:
2.4		 6b3bA-3bazA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 3 LEU A 192
THR A 181
ASN A 182
 None
 0.65A 6baaE-3bazA:
undetectable		 6baaE-3bazA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 3 LEU A 192
THR A 181
ASN A 182
 None
 0.65A 6baaF-3bazA:
undetectable		 6baaF-3bazA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 3 LEU A 192
THR A 181
ASN A 182
 None
 0.65A 6baaG-3bazA:
undetectable		 6baaG-3bazA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		3 / 3 LEU A 192
THR A 181
ASN A 182
 None
 0.65A 6baaH-3bazA:
undetectable		 6baaH-3bazA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE
(Plectranthus
scutellarioides) 		5 / 12 GLY A 254
GLY A 252
ASP A 256
ASP A 106
ILE A 109
 None
None
NAP  A 500 (-3.9A)
None
None
 1.08A 6mhtA-3bazA:
4.5		 6mhtA-3bazA:
22.19