SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TYR_A_9CRA131_1 (TRANSTHYRETIN)	3bb5	STRESS RESPONSIVE ALPHA-BETA PROTEIN (Jannaschia sp. CCS1)	4 / 6	LEU A 33 ALA A 67 LEU A 36 THR A 63	None	1.30A	1tyrA-3bb5A: undetectable	1tyrA-3bb5A: 17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MBS_A_MRVA1101_2 (CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN)	3bb5	STRESS RESPONSIVE ALPHA-BETA PROTEIN (Jannaschia sp. CCS1)	4 / 7	GLN A 78 THR A 76 LEU A 29 THR A 37	None	1.04A	4mbsA-3bb5A: undetectable	4mbsA-3bb5A: 13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MBS_A_MRVA1101_2 (CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN)	3bb5	STRESS RESPONSIVE ALPHA-BETA PROTEIN (Jannaschia sp. CCS1)	4 / 7	GLN A 78 THR A 76 LEU A 29 THR A 61	None	1.02A	4mbsA-3bb5A: undetectable	4mbsA-3bb5A: 13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TRQ_B_ACTB306_0 (WELO5)	3bb5	STRESS RESPONSIVE ALPHA-BETA PROTEIN (Jannaschia sp. CCS1)	3 / 3	GLU A 9 ARG A 53 TYR A 54	None	0.45A	5trqB-3bb5A: undetectable	5trqB-3bb5A: 19.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TYR_A_9CRA131_1","TRANSTHYRETIN","3bb5","STRESS RESPONSIVE ALPHA-BETA PROTEIN","Jannaschia sp. CCS1",4,"LEU A  33;ALA A  67;LEU A  36;THR A  63","None","1.30A","1tyrA-3bb5A:undetectable","1tyrA-3bb5A:17.97"],["4MBS_A_MRVA1101_2","CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN","3bb5","STRESS RESPONSIVE ALPHA-BETA PROTEIN","Jannaschia sp. CCS1",4,"GLN A  78;THR A  76;LEU A  29;THR A  37","None","1.04A","4mbsA-3bb5A:undetectable","4mbsA-3bb5A:13.56"],["4MBS_A_MRVA1101_2","CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN","3bb5","STRESS RESPONSIVE ALPHA-BETA PROTEIN","Jannaschia sp. CCS1",4,"GLN A  78;THR A  76;LEU A  29;THR A  61","None","1.02A","4mbsA-3bb5A:undetectable","4mbsA-3bb5A:13.56"],["5TRQ_B_ACTB306_0","WELO5","3bb5","STRESS RESPONSIVE ALPHA-BETA PROTEIN","Jannaschia sp. CCS1",3,"GLU A   9;ARG A  53;TYR A  54","None","0.45A","5trqB-3bb5A:undetectable","5trqB-3bb5A:19.92"]]