SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3bb6 UNCHARACTERIZED
PROTEIN YEAR
(Escherichia
coli) 		4 / 7 ASP A  32
HIS A  30
ILE A  85
HIS A  83
 ZN  A 128 (-2.9A)
ZN  A 128 (-4.1A)
None
ZN  A 128 (-3.8A)
 1.08A 3t01A-3bb6A:
undetectable		 3t01A-3bb6A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3bb6 UNCHARACTERIZED
PROTEIN YEAR
(Escherichia
coli) 		5 / 11 GLY A  54
LEU A  53
GLN A  65
PHE A  77
ALA A  75
 None
 1.23A 4wnuA-3bb6A:
undetectable		 4wnuA-3bb6A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3bb6 UNCHARACTERIZED
PROTEIN YEAR
(Escherichia
coli) 		4 / 5 PRO A  63
HIS A  30
LEU A   2
PHE A  94
 None
ZN  A 128 (-4.1A)
None
None
 1.41A 5igjA-3bb6A:
undetectable		 5igjA-3bb6A:
16.07