SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 11 LEU A 283
VAL A 279
ILE A 334
VAL A 320
PHE A 307
 None
 1.37A 1gx9A-3bb7A:
undetectable		 1gx9A-3bb7A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 LEU A 142
PRO A 143
LEU A 150
 None
 0.45A 1hrkA-3bb7A:
undetectable		 1hrkA-3bb7A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 9 LYS A 358
PRO A 169
GLY A 258
GLY A 174
GLY A 195
 None
 1.13A 1mxdA-3bb7A:
undetectable		 1mxdA-3bb7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 11 LYS A 358
PRO A 169
GLY A 258
GLY A 174
GLY A 195
 None
 1.09A 1mxgA-3bb7A:
undetectable		 1mxgA-3bb7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 4 THR A 130
LEU A 128
VAL A 308
LEU A 289
 None
 0.89A 1mz9D-3bb7A:
undetectable		 1mz9D-3bb7A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 10 GLY A 311
VAL A 124
GLU A 123
SER A 319
ASP A 310
 None
 1.19A 1pk7C-3bb7A:
undetectable		 1pk7C-3bb7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 10 GLY A 311
VAL A 124
GLU A 123
SER A 319
ASP A 310
 None
 1.24A 1pk9A-3bb7A:
undetectable		 1pk9A-3bb7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 7 ASN A 325
TYR A 138
ASN A 139
VAL A 220
 None
 1.33A 1wu8A-3bb7A:
undetectable
1wu8C-3bb7A:
undetectable		 1wu8A-3bb7A:
21.49
1wu8C-3bb7A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 ASN A 325
TRP A 324
GLN A 161
 None
 1.44A 1xoqA-3bb7A:
undetectable		 1xoqA-3bb7A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 PRO A 169
GLY A 172
TYR A 199
 None
 0.55A 2vouA-3bb7A:
undetectable		 2vouA-3bb7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 PRO A 169
GLY A 172
TYR A 199
 None
 0.52A 2vouB-3bb7A:
undetectable		 2vouB-3bb7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 PRO A 169
GLY A 172
TYR A 199
 None
 0.51A 2vouC-3bb7A:
undetectable		 2vouC-3bb7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 GLY A 174
TYR A 256
SER A 175
 None
 0.64A 2xatA-3bb7A:
undetectable		 2xatA-3bb7A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 TYR A 235
VAL A 229
THR A 152
 None
 0.83A 2ygnA-3bb7A:
undetectable		 2ygnA-3bb7A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 8 GLY A 174
PHE A 257
GLY A 258
PHE A 259
 None
 1.01A 3ko0O-3bb7A:
undetectable
3ko0Q-3bb7A:
undetectable		 3ko0O-3bb7A:
15.26
3ko0Q-3bb7A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 12 VAL A 320
SER A 319
SER A  77
SER A  79
LEU A  93
 None
 1.42A 3vt7A-3bb7A:
undetectable		 3vt7A-3bb7A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 LEU A 142
PRO A 143
LEU A 150
 None
 0.41A 3w1wB-3bb7A:
undetectable		 3w1wB-3bb7A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 9 VAL A 308
GLU A 282
VAL A 355
ILE A 290
ALA A 306
 None
 1.25A 4fwdA-3bb7A:
undetectable		 4fwdA-3bb7A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 12 TYR A 332
GLY A  75
SER A  77
PHE A  81
TYR A  56
 None
 1.21A 4kowA-3bb7A:
undetectable		 4kowA-3bb7A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 12 GLY A 153
MET A 233
THR A 159
ILE A 290
VAL A 352
 None
 1.36A 4okwA-3bb7A:
undetectable		 4okwA-3bb7A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		6 / 12 GLY A 153
GLY A 241
GLY A 237
ASN A 239
THR A 159
ALA A 154
 None
 1.46A 4uckA-3bb7A:
undetectable		 4uckA-3bb7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 6 GLU A 348
GLY A 293
GLY A 292
ASP A 350
 None
 1.00A 5a06D-3bb7A:
undetectable		 5a06D-3bb7A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 12 GLY A 292
LEU A 163
TYR A 199
PHE A 259
GLY A 258
 None
 1.19A 5fsaB-3bb7A:
undetectable		 5fsaB-3bb7A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		5 / 11 TYR A 270
ARG A 267
ILE A 265
ASN A 269
VAL A 352
 None
 1.30A 5hjiA-3bb7A:
undetectable		 5hjiA-3bb7A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		3 / 3 ASP A 350
ASN A 269
PHE A 345
 None
 0.89A 5jglB-3bb7A:
undetectable		 5jglB-3bb7A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 4 VAL A  63
VAL A  53
TYR A  51
GLN A  47
 None
 1.49A 5qggA-3bb7A:
undetectable		 5qggA-3bb7A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 4 VAL A  63
VAL A  53
TYR A  51
GLN A  47
 None
 1.49A 5qgoA-3bb7A:
undetectable		 5qgoA-3bb7A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 4 VAL A  63
VAL A  53
TYR A  51
GLN A  47
 None
 1.48A 5qgpA-3bb7A:
undetectable		 5qgpA-3bb7A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 4 VAL A  63
VAL A  53
TYR A  51
GLN A  47
 None
 1.47A 5qgqA-3bb7A:
undetectable		 5qgqA-3bb7A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 4 VAL A  63
VAL A  53
TYR A  51
GLN A  47
 None
 1.48A 5qhbA-3bb7A:
undetectable		 5qhbA-3bb7A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 5 TYR A 180
TYR A 235
GLY A 236
GLY A 237
 None
 1.10A 5x7pA-3bb7A:
undetectable		 5x7pA-3bb7A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3bb7 INTERPAIN A
(Prevotella
intermedia) 		4 / 5 ALA A 244
SER A 231
GLY A 228
TYR A 235
 None
 1.16A 5yodB-3bb7A:
undetectable		 5yodB-3bb7A:
20.66