SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bb8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 11 VAL A 180
ILE A 162
LYS A 183
ILE A 114
VAL A 146
 None
 1.24A 1gx9A-3bb8A:
undetectable		 1gx9A-3bb8A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 THR A 122
THR A 123
PRO A 121
 PLP  A 500 (-4.5A)
PLP  A 500 (-4.6A)
None
 0.85A 1i3wE-3bb8A:
undetectable		 1i3wE-3bb8A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 THR A 122
THR A 123
PRO A 121
 PLP  A 500 (-4.5A)
PLP  A 500 (-4.6A)
None
 0.83A 1i3wF-3bb8A:
undetectable		 1i3wF-3bb8A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 THR A 122
THR A 123
PRO A 121
 PLP  A 500 (-4.5A)
PLP  A 500 (-4.6A)
None
 0.86A 1i3wG-3bb8A:
undetectable		 1i3wG-3bb8A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 7 VAL A 113
ILE A 114
HIS A 166
LEU A 174
 None
 0.79A 1j96B-3bb8A:
undetectable		 1j96B-3bb8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 THR A 123
PRO A 121
THR A 122
 PLP  A 500 (-4.6A)
None
PLP  A 500 (-4.5A)
 0.82A 1mnvD-3bb8A:
undetectable		 1mnvD-3bb8A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 THR A 122
THR A 123
PRO A 121
 PLP  A 500 (-4.5A)
PLP  A 500 (-4.6A)
None
 0.79A 1mnvD-3bb8A:
undetectable		 1mnvD-3bb8A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 THR A 122
THR A 123
PRO A 121
 PLP  A 500 (-4.5A)
PLP  A 500 (-4.6A)
None
 0.84A 1qfiA-3bb8A:
undetectable		 1qfiA-3bb8A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 6 ALA A  93
LEU A  91
SER A  88
SER A  85
 None
None
None
PLP  A 500 (-3.5A)
 1.00A 1tz8C-3bb8A:
undetectable
1tz8D-3bb8A:
undetectable		 1tz8C-3bb8A:
15.40
1tz8D-3bb8A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 8 PHE A 231
ALA A 205
HIS A 166
LEU A 174
 None
 1.10A 1x8vA-3bb8A:
undetectable		 1x8vA-3bb8A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 12 LEU A 289
LYS A 290
GLY A 248
TYR A 287
ASP A 246
 None
 1.06A 2br4B-3bb8A:
2.3		 2br4B-3bb8A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 THR A 408
PRO A 348
TYR A 144
 None
 0.91A 2dxrA-3bb8A:
undetectable		 2dxrA-3bb8A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 12 PHE A 216
TYR A 217
ALA A  89
SER A  87
ALA A 229
 None
PLP  A 500 ( 4.7A)
None
PLP  A 500 (-2.5A)
None
 1.21A 2igtC-3bb8A:
3.0		 2igtC-3bb8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 12 MET A 204
LEU A  75
ALA A 195
VAL A 214
TYR A  74
 None
 1.06A 2japB-3bb8A:
undetectable		 2japB-3bb8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 8 LEU A  75
VAL A 310
ILE A 222
PHE A 216
 None
 0.97A 2weyB-3bb8A:
undetectable		 2weyB-3bb8A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 12 LEU A 168
THR A 408
SER A 355
PHE A 429
PHE A 433
 None
None
BEN  A   1 (-4.9A)
None
BEN  A   1 (-4.7A)
 1.47A 2y01B-3bb8A:
undetectable		 2y01B-3bb8A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 5 VAL A 394
VAL A 395
THR A 399
ARG A 393
 None
 1.08A 3bjwA-3bb8A:
undetectable		 3bjwA-3bb8A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 5 VAL A 394
VAL A 395
THR A 399
ARG A 393
 None
 1.04A 3bjwC-3bb8A:
undetectable		 3bjwC-3bb8A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 12 ARG A 359
PRO A 348
GLY A 412
SER A  37
LEU A 375
 None
 1.29A 3okxB-3bb8A:
undetectable		 3okxB-3bb8A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 5 SER A 355
GLN A 407
SER A 358
VAL A 357
 BEN  A   1 (-4.9A)
None
None
BEN  A   1 ( 4.3A)
 1.41A 4a99D-3bb8A:
undetectable		 4a99D-3bb8A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 5 LEU A 107
ILE A 189
ALA A  96
MET A 163
 None
 1.07A 4dc3B-3bb8A:
undetectable		 4dc3B-3bb8A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 8 VAL A 425
HIS A 419
ASP A 423
ASN A 316
 None
 0.86A 4exsB-3bb8A:
undetectable		 4exsB-3bb8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 THR A 123
PRO A 121
THR A 122
 PLP  A 500 (-4.6A)
None
PLP  A 500 (-4.5A)
 0.80A 4hivD-3bb8A:
undetectable		 4hivD-3bb8A:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 8 VAL A 177
LEU A 188
ILE A 211
THR A 123
 None
None
None
PLP  A 500 (-4.6A)
 0.78A 4ma7A-3bb8A:
undetectable		 4ma7A-3bb8A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 12 LEU A 196
GLY A 299
LEU A  48
GLU A 304
LEU A 303
 None
 1.03A 4x61A-3bb8A:
2.2		 4x61A-3bb8A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 6 ALA A 301
GLN A 302
LEU A  48
MET A  49
 None
 1.01A 4xoyA-3bb8A:
undetectable		 4xoyA-3bb8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 6 ALA A 301
GLN A 302
LEU A  48
MET A  49
 None
 1.05A 4xp3A-3bb8A:
undetectable		 4xp3A-3bb8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		3 / 3 HIS A 221
LYS A 220
PHE A 345
 None
PLP  A 500 (-1.3A)
None
 1.39A 5klaA-3bb8A:
undetectable		 5klaA-3bb8A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 12 ALA A 175
LEU A 188
ILE A 162
VAL A 146
ASP A 191
 None
None
None
None
PLP  A 500 (-3.1A)
 1.22A 5vlmG-3bb8A:
undetectable		 5vlmG-3bb8A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 5 LEU A 237
THR A  98
ARG A 245
ARG A 249
 None
 1.23A 6ew0B-3bb8A:
undetectable		 6ew0B-3bb8A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 5 LEU A 237
THR A  98
ARG A 245
ARG A 249
 None
 1.23A 6ew0D-3bb8A:
undetectable		 6ew0D-3bb8A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 5 LEU A 237
THR A  98
ARG A 245
ARG A 249
 None
 1.23A 6ew0H-3bb8A:
undetectable		 6ew0H-3bb8A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		4 / 5 LEU A 237
THR A  98
ARG A 245
ARG A 249
 None
 1.23A 6ew0I-3bb8A:
undetectable		 6ew0I-3bb8A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE
(Yersinia
pseudotuberculos
is) 		5 / 12 ASP A 293
ASN A  64
ARG A 245
GLU A 242
GLY A 228
 None
 1.36A 6gnfC-3bb8A:
undetectable		 6gnfC-3bb8A:
21.65