SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 LEU A 142
PRO A 143
LEU A 150
 None
 0.40A 1hrkA-3bbaA:
undetectable		 1hrkA-3bbaA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		5 / 12 GLY A 311
VAL A 124
GLU A 123
SER A 319
ASP A 310
 None
 1.29A 1jdvE-3bbaA:
undetectable
1jdvF-3bbaA:
undetectable		 1jdvE-3bbaA:
24.66
1jdvF-3bbaA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3bba INTERPAIN A
(Prevotella
intermedia) 		4 / 4 THR A 130
LEU A 128
VAL A 308
LEU A 289
 None
 0.91A 1mz9D-3bbaA:
undetectable		 1mz9D-3bbaA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		4 / 8 GLY A 311
VAL A 124
GLU A 123
SER A 319
 None
 0.88A 1pk7B-3bbaA:
undetectable		 1pk7B-3bbaA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		5 / 10 GLY A 311
VAL A 124
GLU A 123
SER A 319
ASP A 310
 None
 1.23A 1pk7C-3bbaA:
undetectable		 1pk7C-3bbaA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		5 / 10 GLY A 311
VAL A 124
GLU A 123
SER A 319
ASP A 310
 None
 1.29A 1pk9A-3bbaA:
undetectable		 1pk9A-3bbaA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3bba INTERPAIN A
(Prevotella
intermedia) 		4 / 7 MET A 224
GLN A 134
ALA A 158
ASN A 321
 None
 1.32A 1t9wA-3bbaA:
undetectable		 1t9wA-3bbaA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3bba INTERPAIN A
(Prevotella
intermedia) 		4 / 7 ASN A 325
TYR A 138
ASN A 139
VAL A 220
 None
 1.32A 1wu8A-3bbaA:
undetectable
1wu8C-3bbaA:
undetectable		 1wu8A-3bbaA:
22.06
1wu8C-3bbaA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3bba INTERPAIN A
(Prevotella
intermedia) 		5 / 12 GLY A 133
GLY A 153
THR A 131
ASN A 139
PRO A 137
 None
 1.09A 2okcA-3bbaA:
undetectable		 2okcA-3bbaA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 LEU A 142
PRO A 143
LEU A 150
 None
 0.50A 2qd5B-3bbaA:
undetectable		 2qd5B-3bbaA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 PRO A 169
GLY A 172
TYR A 199
 None
 0.51A 2vouA-3bbaA:
undetectable		 2vouA-3bbaA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 PRO A 169
GLY A 172
TYR A 199
 None
 0.52A 2vouB-3bbaA:
undetectable		 2vouB-3bbaA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 PRO A 169
GLY A 172
TYR A 199
 None
 0.51A 2vouC-3bbaA:
undetectable		 2vouC-3bbaA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 GLY A 174
TYR A 256
SER A 175
 None
 0.63A 2xatA-3bbaA:
undetectable		 2xatA-3bbaA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 TYR A 235
VAL A 229
THR A 152
 None
 0.80A 2ygnA-3bbaA:
undetectable		 2ygnA-3bbaA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		5 / 12 ALA A 306
GLY A 304
VAL A 294
GLY A 293
VAL A 155
 None
 1.10A 3f8wA-3bbaA:
undetectable		 3f8wA-3bbaA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		5 / 12 ALA A 306
GLY A 304
VAL A 294
GLY A 293
VAL A 155
 None
 1.13A 3f8wC-3bbaA:
undetectable		 3f8wC-3bbaA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bba INTERPAIN A
(Prevotella
intermedia) 		4 / 7 VAL A 320
VAL A 318
LEU A 317
VAL A 112
 None
 0.87A 3hs6B-3bbaA:
undetectable		 3hs6B-3bbaA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 3bba INTERPAIN A
(Prevotella
intermedia) 		5 / 12 ASP A 350
ILE A 265
VAL A 318
ILE A 278
TYR A 270
 None
 1.18A 3ohtA-3bbaA:
undetectable
3ohtB-3bbaA:
undetectable		 3ohtA-3bbaA:
19.74
3ohtB-3bbaA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 LEU A 142
PRO A 143
LEU A 150
 None
 0.38A 3w1wB-3bbaA:
undetectable		 3w1wB-3bbaA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		3 / 3 LEU A 337
VAL A 328
ASP A 329
 None
 0.52A 4y8wC-3bbaA:
undetectable		 4y8wC-3bbaA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		4 / 5 SER A 295
VAL A 294
GLY A 304
ALA A 303
 None
 0.95A 5k50A-3bbaA:
undetectable		 5k50A-3bbaA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3bba INTERPAIN A
(Prevotella
intermedia) 		4 / 5 ALA A 244
SER A 231
GLY A 228
TYR A 235
 None
 1.19A 5yodB-3bbaA:
undetectable		 5yodB-3bbaA:
22.75