SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 11 ILE A 166
GLY A 153
PHE A 152
TYR A 134
VAL A 198
 None
 1.24A 1axwB-3bblA:
undetectable		 1axwB-3bblA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.06A 1c9sN-3bblA:
undetectable
1c9sO-3bblA:
undetectable		 1c9sN-3bblA:
14.08
1c9sO-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 11 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.05A 1c9sP-3bblA:
undetectable
1c9sQ-3bblA:
undetectable		 1c9sP-3bblA:
14.08
1c9sQ-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 9 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.06A 1c9sQ-3bblA:
undetectable
1c9sR-3bblA:
undetectable		 1c9sQ-3bblA:
14.08
1c9sR-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.08A 1c9sL-3bblA:
undetectable
1c9sV-3bblA:
undetectable		 1c9sL-3bblA:
14.08
1c9sV-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 9 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.12A 1gtfD-3bblA:
undetectable
1gtfE-3bblA:
undetectable		 1gtfD-3bblA:
14.08
1gtfE-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.11A 1gtfJ-3bblA:
undetectable
1gtfK-3bblA:
undetectable		 1gtfJ-3bblA:
14.08
1gtfK-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 11 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.07A 1gtfQ-3bblA:
undetectable
1gtfR-3bblA:
undetectable		 1gtfQ-3bblA:
14.08
1gtfR-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 9 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.07A 1gtfR-3bblA:
undetectable
1gtfS-3bblA:
undetectable		 1gtfR-3bblA:
14.08
1gtfS-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 11 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.07A 1gtfS-3bblA:
undetectable
1gtfT-3bblA:
undetectable		 1gtfS-3bblA:
14.08
1gtfT-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 11 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.07A 1gtnT-3bblA:
undetectable
1gtnU-3bblA:
undetectable		 1gtnT-3bblA:
14.08
1gtnU-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 9 LEU A 328
ASP A 165
GLY A 153
ILE A 302
PRO A 331
 None
 0.99A 1hpvA-3bblA:
undetectable		 1hpvA-3bblA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 12 LEU A 179
GLU A 218
ARG A 246
LEU A 277
ILE A 280
 None
 1.00A 1s9pD-3bblA:
undetectable		 1s9pD-3bblA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 7 THR A  73
GLU A 107
SER A 131
VAL A 198
 None
 1.16A 1tv8A-3bblA:
undetectable		 1tv8A-3bblA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 7 THR A  73
GLU A 107
SER A 131
VAL A 198
 None
 1.11A 1tv8B-3bblA:
undetectable		 1tv8B-3bblA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.10A 1utdE-3bblA:
undetectable
1utdF-3bblA:
undetectable		 1utdE-3bblA:
14.08
1utdF-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.11A 1utdH-3bblA:
undetectable
1utdI-3bblA:
undetectable		 1utdH-3bblA:
14.08
1utdI-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 11 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.10A 1utdS-3bblA:
undetectable
1utdT-3bblA:
undetectable		 1utdS-3bblA:
14.08
1utdT-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 281
ALA A 262
THR A 253
ILE A 279
GLY A 227
 None
 1.08A 1utdU-3bblA:
undetectable
1utdV-3bblA:
undetectable		 1utdU-3bblA:
14.08
1utdV-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 11 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.11A 1utdL-3bblA:
undetectable
1utdV-3bblA:
undetectable		 1utdL-3bblA:
14.08
1utdV-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 12 GLY A 122
SER A  63
VAL A 317
LEU A 101
LEU A 313
 None
 1.00A 1ya4C-3bblA:
2.8		 1ya4C-3bblA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 8 THR A  73
GLU A 107
SER A 131
VAL A 198
 None
 1.10A 2fb2A-3bblA:
undetectable		 2fb2A-3bblA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 7 THR A  73
GLU A 107
SER A 131
VAL A 198
 None
 1.07A 2fb2B-3bblA:
undetectable		 2fb2B-3bblA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 7 ILE A 279
ILE A 334
LEU A 333
ILE A 335
 None
 0.83A 2q83A-3bblA:
undetectable		 2q83A-3bblA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 8 MET A 263
ALA A 264
GLY A 261
ILE A 260
 EDO  A 503 (-4.5A)
EDO  A 503 (-3.7A)
None
None
 0.58A 2zm9A-3bblA:
undetectable		 2zm9A-3bblA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 12 GLY A 205
THR A 169
ILE A 189
ASP A 201
LEU A 203
 None
 1.30A 3iv6D-3bblA:
undetectable		 3iv6D-3bblA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 12 ARG A 154
LEU A 328
GLY A 171
VAL A 176
LEU A 254
 None
 1.05A 3ku1H-3bblA:
undetectable		 3ku1H-3bblA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 12 LEU A 328
ASP A 165
GLY A 153
ILE A 302
PRO A 331
 None
 1.00A 3nu5B-3bblA:
undetectable		 3nu5B-3bblA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 5 TYR A  68
SER A  87
ASP A 165
ILE A 166
 None
 1.28A 3uj7B-3bblA:
undetectable		 3uj7B-3bblA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		3 / 3 GLN A  84
ASP A 284
GLN A 289
 None
 0.88A 4aztA-3bblA:
undetectable		 4aztA-3bblA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 12 LEU A 271
ALA A 266
LEU A 295
GLY A 281
LEU A 190
 None
None
EDO  A 501 (-4.3A)
None
None
 1.03A 4dm8B-3bblA:
undetectable		 4dm8B-3bblA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 6 ARG A 202
GLY A 199
ASN A 133
MET A 235
 None
 1.17A 4g0vB-3bblA:
3.0		 4g0vB-3bblA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 6 SER A 196
GLY A 171
ASP A 167
GLY A 205
 None
 1.04A 4koeA-3bblA:
undetectable
4koeB-3bblA:
undetectable
4koeC-3bblA:
3.8		 4koeA-3bblA:
22.82
4koeB-3bblA:
22.82
4koeC-3bblA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 8 PHE A 152
VAL A 198
SER A 130
GLY A 153
 None
 0.84A 4m48A-3bblA:
undetectable		 4m48A-3bblA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		4 / 6 GLY A 171
ASP A 167
GLY A 205
SER A 196
 None
 1.03A 4z53A-3bblA:
undetectable
4z53B-3bblA:
undetectable		 4z53A-3bblA:
17.61
4z53B-3bblA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.10A 5eevA-3bblA:
undetectable
5eevB-3bblA:
undetectable		 5eevA-3bblA:
14.08
5eevB-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.09A 5eewA-3bblA:
undetectable
5eewB-3bblA:
undetectable		 5eewA-3bblA:
14.08
5eewB-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.10A 5eexA-3bblA:
undetectable
5eexB-3bblA:
undetectable		 5eexA-3bblA:
14.08
5eexB-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.09A 5eeyA-3bblA:
undetectable
5eeyB-3bblA:
undetectable		 5eeyA-3bblA:
14.08
5eeyB-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.09A 5eezA-3bblA:
undetectable
5eezB-3bblA:
undetectable		 5eezA-3bblA:
14.08
5eezB-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.09A 5ef0A-3bblA:
undetectable
5ef0B-3bblA:
undetectable		 5ef0A-3bblA:
14.08
5ef0B-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.09A 5ef1A-3bblA:
undetectable
5ef1B-3bblA:
undetectable		 5ef1A-3bblA:
14.08
5ef1B-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.09A 5ef2A-3bblA:
undetectable
5ef2B-3bblA:
undetectable		 5ef2A-3bblA:
14.08
5ef2B-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 10 GLY A 227
GLY A 281
ALA A 262
THR A 253
ILE A 279
 None
 1.09A 5ef3A-3bblA:
undetectable
5ef3B-3bblA:
undetectable		 5ef3A-3bblA:
14.08
5ef3B-3bblA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 12 LEU A 328
ASP A 165
GLY A 153
ILE A 302
PRO A 331
 None
 1.03A 6dh3B-3bblA:
undetectable		 6dh3B-3bblA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 3bbl REGULATORY PROTEIN
OF LACI FAMILY
(Chloroflexus
aggregans) 		5 / 12 LEU A 328
ASP A 165
GLY A 153
ILE A 302
PRO A 331
 None
 1.01A 6dh6B-3bblA:
undetectable		 6dh6B-3bblA:
15.27