SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		3 / 3 ALA A  22
VAL A  24
TRP A  23
 None
 0.85A 1bdwA-3bbyA:
undetectable
1bdwB-3bbyA:
undetectable		 1bdwA-3bbyA:
6.80
1bdwB-3bbyA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		4 / 5 ASP A 183
LEU A 178
MET A 174
ARG A 120
 None
 1.33A 2gj5A-3bbyA:
undetectable		 2gj5A-3bbyA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		5 / 11 ASN A 176
ILE A 206
THR A 194
ALA A 193
VAL A  24
 None
 1.23A 2gl0B-3bbyA:
undetectable
2gl0C-3bbyA:
undetectable		 2gl0B-3bbyA:
21.66
2gl0C-3bbyA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		5 / 12 ASN A 176
ILE A 206
THR A 194
ALA A 193
VAL A  24
 None
 1.30A 2gl0D-3bbyA:
undetectable
2gl0E-3bbyA:
undetectable		 2gl0D-3bbyA:
21.66
2gl0E-3bbyA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_E_ADNE905_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		5 / 11 ASN A 176
ILE A 206
THR A 194
ALA A 193
VAL A  24
 None
 1.24A 2gl0E-3bbyA:
undetectable
2gl0F-3bbyA:
undetectable		 2gl0E-3bbyA:
21.66
2gl0F-3bbyA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		5 / 11 ASN A 176
ILE A 206
THR A 194
ALA A 193
VAL A  24
 None
 1.22A 2gl0D-3bbyA:
undetectable
2gl0F-3bbyA:
undetectable		 2gl0D-3bbyA:
21.66
2gl0F-3bbyA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		4 / 5 TYR A  78
ILE A  64
LEU A  26
LEU A  31
 None
 1.16A 2zb7A-3bbyA:
undetectable		 2zb7A-3bbyA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		4 / 5 LEU A 134
ARG A 177
ARG A 120
ARG A 117
 None
 1.40A 3ticA-3bbyA:
undetectable		 3ticA-3bbyA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		4 / 6 GLN A 196
VAL A  24
LEU A 153
ARG A 101
 None
 1.30A 6brdB-3bbyA:
undetectable		 6brdB-3bbyA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3bby UNCHARACTERIZED
GST-LIKE PROTEIN
YFCF
(Escherichia
coli) 		3 / 3 TRP A 164
GLU A 163
GLU A  89
 None
None
CA  A 216 (-3.2A)
 0.74A 6fhwA-3bbyA:
3.2		 6fhwA-3bbyA:
20.61