SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bc8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 VAL A 125
ILE A 294
ILE A  95
ASN A 115
LEU A 326
 None
 1.19A 1fm4A-3bc8A:
undetectable		 1fm4A-3bc8A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 5 LEU A  55
SER A 328
LEU A 121
LEU A 320
 None
None
None
EDO  A 502 (-3.9A)
 0.98A 1yajD-3bc8A:
2.4		 1yajD-3bc8A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 8 PHE A 450
LEU A 352
LEU A 458
LEU A 391
 None
 0.84A 2bfpC-3bc8A:
undetectable		 2bfpC-3bc8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 8 PHE A 450
LEU A 352
LEU A 458
LEU A 391
 None
 0.86A 2bfpD-3bc8A:
undetectable		 2bfpD-3bc8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 9 LEU A 454
PHE A 450
LEU A 458
LEU A 377
ALA A 356
 None
 1.40A 2bxeA-3bc8A:
undetectable		 2bxeA-3bc8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 9 GLY A  45
LEU A 329
TYR A 334
LEU A 128
LEU A  35
 None
 1.08A 2npnA-3bc8A:
undetectable		 2npnA-3bc8A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 ILE A 380
ALA A 432
VAL A 400
LEU A 391
LEU A 352
 None
 1.00A 2rctA-3bc8A:
undetectable		 2rctA-3bc8A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		3 / 3 LEU A 320
ARG A  86
ASN A  64
 EDO  A 502 (-3.9A)
None
None
 0.68A 3qxvD-3bc8A:
undetectable		 3qxvD-3bc8A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		3 / 3 LEU A 408
ARG A 362
ASN A 435
 None
 0.69A 3qxvD-3bc8A:
undetectable		 3qxvD-3bc8A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 9 ASP A  62
GLY A 110
GLY A  96
ILE A  95
ILE A  92
 None
 0.99A 3s53A-3bc8A:
undetectable		 3s53A-3bc8A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 4 SER A 174
ASP A 283
ASP A 321
ALA A 143
 LLP  A 284 ( 2.7A)
LLP  A 284 ( 3.2A)
None
LLP  A 284 ( 3.3A)
 1.33A 3uj6A-3bc8A:
3.2		 3uj6A-3bc8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 7 ARG A 230
ASN A 191
GLU A 194
ASN A 369
 None
 1.12A 4d39B-3bc8A:
undetectable		 4d39B-3bc8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 ILE A 380
ALA A 432
VAL A 400
LEU A 391
LEU A 352
 None
 1.11A 4qynA-3bc8A:
undetectable		 4qynA-3bc8A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 ILE A 380
ALA A 432
VAL A 400
LEU A 391
LEU A 352
 None
 1.03A 4qzuC-3bc8A:
undetectable		 4qzuC-3bc8A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 GLN A 280
LEU A 123
GLY A 297
ALA A 135
PHE A 298
 None
 1.27A 4retA-3bc8A:
undetectable		 4retA-3bc8A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 GLN A 280
LEU A 123
GLY A 297
ALA A 135
PHE A 298
 None
 1.26A 4retC-3bc8A:
undetectable		 4retC-3bc8A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		3 / 3 VAL A 406
PHE A 422
ARG A 169
 None
 0.96A 4xr4B-3bc8A:
3.6		 4xr4B-3bc8A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 6 ASP A 171
PRO A 430
TYR A 433
LEU A 364
 None
 1.15A 5bmvB-3bc8A:
undetectable		 5bmvB-3bc8A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXF_B_BEZB601_0
(EUGENOL OXIDASE)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 10 ASP A 385
VAL A 388
GLN A 465
ILE A 380
VAL A 461
 None
 1.40A 5fxfB-3bc8A:
0.5		 5fxfB-3bc8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 ASP A 283
PRO A 289
GLY A 292
THR A 144
SER A 317
 LLP  A 284 ( 3.2A)
None
None
LLP  A 284 ( 4.4A)
EDO  A 502 (-3.1A)
 1.23A 5hfjA-3bc8A:
2.2		 5hfjA-3bc8A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 LEU A 377
LEU A 458
PHE A 450
ALA A 436
LEU A 352
 None
 1.15A 5iepA-3bc8A:
undetectable		 5iepA-3bc8A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 5 VAL A 250
ASP A 276
PRO A 248
ALA A 277
 None
 1.10A 5otrA-3bc8A:
undetectable		 5otrA-3bc8A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 10 PRO A 168
ILE A 247
VAL A 205
LEU A 202
GLU A 237
 None
 1.31A 5tixB-3bc8A:
undetectable		 5tixB-3bc8A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 7 THR A 154
PHE A 152
LEU A 148
SER A 222
 None
 1.08A 5uxcA-3bc8A:
undetectable		 5uxcA-3bc8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 12 LEU A  55
ASP A 321
PRO A 289
PHE A 286
THR A 325
 None
 1.29A 5x6yC-3bc8A:
undetectable		 5x6yC-3bc8A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		4 / 7 LEU A 114
ILE A 117
THR A 118
PHE A  54
 None
 0.93A 5zsfA-3bc8A:
undetectable
5zsfB-3bc8A:
undetectable		 5zsfA-3bc8A:
10.59
5zsfB-3bc8A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 9 LEU A 454
GLY A 392
LEU A 391
GLN A 390
VAL A 400
 None
 1.32A 6czmA-3bc8A:
0.9
6czmB-3bc8A:
0.9		 6czmA-3bc8A:
20.80
6czmB-3bc8A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE
(Mus
musculus) 		5 / 9 LEU A 454
GLY A 392
LEU A 391
GLN A 390
VAL A 400
 None
 1.27A 6czmB-3bc8A:
0.9
6czmC-3bc8A:
undetectable		 6czmB-3bc8A:
20.80
6czmC-3bc8A:
20.80