SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bch'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IIU_A_RTLA176_0 (PLASMA RETINOL-BINDING PROTEIN)	3bch	40S RIBOSOMAL PROTEIN SA (Homo sapiens)	5 / 11	LEU A 58 LEU A 173 ALA A 20 LEU A 51 ARG A 180	None	1.25A	1iiuA-3bchA: undetectable	1iiuA-3bchA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P73_A_ACTA275_0 (MHC RFP-Y CLASS I ALPHA CHAIN)	3bch	40S RIBOSOMAL PROTEIN SA (Homo sapiens)	3 / 3	ILE A 65 VAL A 182 ARG A 186	None	0.53A	3p73A-3bchA: undetectable	3p73A-3bchA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U7S_A_017A201_2 (POL POLYPROTEIN)	3bch	40S RIBOSOMAL PROTEIN SA (Homo sapiens)	5 / 9	ALA A 146 ASP A 130 ILE A 77 ILE A 65 PRO A 143	None	1.25A	3u7sB-3bchA: undetectable	3u7sB-3bchA: 15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GTQ_B_ACTB207_0 (DUF1778 DOMAIN-CONTAINING PROTEIN N-ACETYLTRANSFERASE)	3bch	40S RIBOSOMAL PROTEIN SA (Homo sapiens)	4 / 6	LEU A 183 THR A 188 GLY A 187 ARG A 191	None	1.11A	6gtqB-3bchA: undetectable 6gtqD-3bchA: undetectable	6gtqB-3bchA: 20.93 6gtqD-3bchA: 10.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IIU_A_RTLA176_0","PLASMA RETINOL-BINDING PROTEIN","3bch","40S RIBOSOMAL PROTEIN SA","Homo sapiens",5,"LEU A  58;LEU A 173;ALA A  20;LEU A  51;ARG A 180","None","1.25A","1iiuA-3bchA:undetectable","1iiuA-3bchA:21.43"],["3P73_A_ACTA275_0","MHC RFP-Y CLASS I ALPHA CHAIN","3bch","40S RIBOSOMAL PROTEIN SA","Homo sapiens",3,"ILE A  65;VAL A 182;ARG A 186","None","0.53A","3p73A-3bchA:undetectable","3p73A-3bchA:22.76"],["3U7S_A_017A201_2","POL POLYPROTEIN;POL POLYPROTEIN","3bch","40S RIBOSOMAL PROTEIN SA","Homo sapiens",5,"ALA A 146;ASP A 130;ILE A  77;ILE A  65;PRO A 143","None","1.25A","3u7sB-3bchA:undetectable","3u7sB-3bchA:15.68"],["6GTQ_B_ACTB207_0","DUF1778 DOMAIN-CONTAINING PROTEIN;N-ACETYLTRANSFERASE","3bch","40S RIBOSOMAL PROTEIN SA","Homo sapiens",4,"LEU A 183;THR A 188;GLY A 187;ARG A 191","None","1.11A","6gtqB-3bchA:undetectable;6gtqD-3bchA:undetectable","6gtqB-3bchA:20.93;6gtqD-3bchA:10.82"]]