SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bcw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 3bcw UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 PRO A  99
MET A  98
HIS A  88
ASP A  94
 None
ACT  A 123 ( 4.1A)
None
None
 1.20A 2lh8A-3bcwA:
undetectable		 2lh8A-3bcwA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3bcw UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 TYR A  67
SER A  62
TRP A 106
VAL A  90
HIS A  72
 EDO  A 127 (-4.0A)
ACT  A 123 (-2.7A)
ACT  A 123 ( 4.1A)
None
None
 1.43A 3vt3A-3bcwA:
undetectable		 3vt3A-3bcwA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 3bcw UNCHARACTERIZED
PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 THR A 103
ASN A  63
SER A  62
 None
None
ACT  A 123 (-2.7A)
 0.54A 4tvtA-3bcwA:
undetectable		 4tvtA-3bcwA:
20.47