SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bd9 HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
5
(Homo
sapiens) 		3 / 3 LEU A 263
PRO A 262
LEU A 266
 None
 0.57A 2po5B-3bd9A:
3.4		 2po5B-3bd9A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bd9 HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
5
(Homo
sapiens) 		3 / 3 LEU A 263
PRO A 262
LEU A 266
 None
 0.57A 2po7B-3bd9A:
3.6		 2po7B-3bd9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3bd9 HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
5
(Homo
sapiens) 		4 / 5 ILE A 169
PRO A 166
TYR A 244
TYR A 170
 None
 1.19A 3d9lA-3bd9A:
undetectable
3d9lY-3bd9A:
undetectable		 3d9lA-3bd9A:
17.54
3d9lY-3bd9A:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bd9 HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
5
(Homo
sapiens) 		4 / 5 LEU A 263
PRO A 262
LEU A 266
ILE A 279
 None
 1.06A 4klrA-3bd9A:
3.6		 4klrA-3bd9A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 3bd9 HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
5
(Homo
sapiens) 		4 / 6 ARG A 188
PHE A 331
ILE A 338
THR A 339
 None
 0.99A 5vceA-3bd9A:
undetectable		 5vceA-3bd9A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3bd9 HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
5
(Homo
sapiens) 		3 / 3 LEU A 263
GLN A 281
LYS A 271
 None
 0.90A 6exiB-3bd9A:
undetectable		 6exiB-3bd9A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 3bd9 HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
5
(Homo
sapiens) 		3 / 3 LEU A 263
GLN A 281
LYS A 271
 None
 0.88A 6exiA-3bd9A:
undetectable		 6exiA-3bd9A:
15.30