SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bdd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RX3_A_MTXA161_2 (DIHYDROFOLATE REDUCTASE)	3bdd	REGULATORY PROTEIN MARR (Streptococcus suis)	3 / 3	LYS A 66 ILE A 35 THR A 91	None	0.69A	1rx3A-3bddA: undetectable	1rx3A-3bddA: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XVA_B_ACTB294_0 (GLYCINE N-METHYLTRANSFERASE)	3bdd	REGULATORY PROTEIN MARR (Streptococcus suis)	4 / 6	ALA A 94 TYR A 33 ILE A 28 LEU A 40	None None PO4 A 142 (-4.0A) None	1.05A	1xvaA-3bddA: undetectable 1xvaB-3bddA: undetectable	1xvaA-3bddA: 19.45 1xvaB-3bddA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GH8_A_MTXA201_2 (DIHYDROFOLATE REDUCTASE)	3bdd	REGULATORY PROTEIN MARR (Streptococcus suis)	3 / 3	LYS A 66 ILE A 35 THR A 91	None	0.74A	4gh8A-3bddA: undetectable	4gh8A-3bddA: 18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA505_0 (FERROCHELATASE, MITOCHONDRIAL)	3bdd	REGULATORY PROTEIN MARR (Streptococcus suis)	4 / 5	LEU A 36 LEU A 39 ILE A 74 ARG A 76	None	1.05A	4klrA-3bddA: undetectable	4klrA-3bddA: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBR_A_ACTA608_0 (SERUM ALBUMIN)	3bdd	REGULATORY PROTEIN MARR (Streptococcus suis)	3 / 3	LYS A 66 ARG A 32 HIS A 64	None GOL A 144 ( 3.2A) GOL A 144 (-4.5A)	0.94A	4zbrA-3bddA: undetectable	4zbrA-3bddA: 11.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RX3_A_MTXA161_2","DIHYDROFOLATE REDUCTASE","3bdd","REGULATORY PROTEIN MARR","Streptococcus suis",3,"LYS A  66;ILE A  35;THR A  91","None","0.69A","1rx3A-3bddA:undetectable","1rx3A-3bddA:20.37"],["1XVA_B_ACTB294_0","GLYCINE N-METHYLTRANSFERASE","3bdd","REGULATORY PROTEIN MARR","Streptococcus suis",4,"ALA A  94;TYR A  33;ILE A  28;LEU A  40","None;None;PO4 A 142 (-4.0A);None","1.05A","1xvaA-3bddA:undetectable;1xvaB-3bddA:undetectable","1xvaA-3bddA:19.45;1xvaB-3bddA:19.45"],["4GH8_A_MTXA201_2","DIHYDROFOLATE REDUCTASE","3bdd","REGULATORY PROTEIN MARR","Streptococcus suis",3,"LYS A  66;ILE A  35;THR A  91","None","0.74A","4gh8A-3bddA:undetectable","4gh8A-3bddA:18.82"],["4KLR_A_CHDA505_0","FERROCHELATASE, MITOCHONDRIAL","3bdd","REGULATORY PROTEIN MARR","Streptococcus suis",4,"LEU A  36;LEU A  39;ILE A  74;ARG A  76","None","1.05A","4klrA-3bddA:undetectable","4klrA-3bddA:18.66"],["4ZBR_A_ACTA608_0","SERUM ALBUMIN","3bdd","REGULATORY PROTEIN MARR","Streptococcus suis",3,"LYS A  66;ARG A  32;HIS A  64","None;GOL A 144 ( 3.2A);GOL A 144 (-4.5A)","0.94A","4zbrA-3bddA:undetectable","4zbrA-3bddA:11.66"]]