SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M8E_B_H4BB903_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3bdq	STEROL CARRIER PROTEIN 2-LIKE 2 (Aedes aegypti)	3 / 3	ARG A 0 ILE A 33 TRP A 42	None	1.09A	1m8eB-3bdqA: undetectable	1m8eB-3bdqA: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	3bdq	STEROL CARRIER PROTEIN 2-LIKE 2 (Aedes aegypti)	4 / 8	VAL A 51 LEU A 49 VAL A 17 VAL A 104	None None PLM A 300 ( 4.9A) PLM A 300 ( 4.9A)	0.91A	2bdmA-3bdqA: undetectable	2bdmA-3bdqA: 15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZG_A_NCAA302_0 (ADP-RIBOSYL CYCLASE 1)	3bdq	STEROL CARRIER PROTEIN 2-LIKE 2 (Aedes aegypti)	4 / 7	LEU A 67 GLU A 68 ASP A 69 SER A 2	None	1.30A	3dzgA-3bdqA: undetectable	3dzgA-3bdqA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZG_B_NCAB302_0 (ADP-RIBOSYL CYCLASE 1)	3bdq	STEROL CARRIER PROTEIN 2-LIKE 2 (Aedes aegypti)	4 / 7	LEU A 67 GLU A 68 ASP A 69 SER A 2	None	1.28A	3dzgB-3bdqA: undetectable	3dzgB-3bdqA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E68_A_H4BA902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3bdq	STEROL CARRIER PROTEIN 2-LIKE 2 (Aedes aegypti)	3 / 3	ARG A 0 ILE A 33 TRP A 42	None	1.05A	3e68A-3bdqA: undetectable	3e68A-3bdqA: 14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E6T_B_H4BB902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3bdq	STEROL CARRIER PROTEIN 2-LIKE 2 (Aedes aegypti)	3 / 3	ARG A 0 ILE A 33 TRP A 42	None	1.08A	3e6tB-3bdqA: undetectable	3e6tB-3bdqA: 14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HRD_E_NIOE5660_1 (NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT)	3bdq	STEROL CARRIER PROTEIN 2-LIKE 2 (Aedes aegypti)	3 / 3	GLU A 4 GLU A 8 TRP A 42	None	1.09A	3hrdA-3bdqA: undetectable 3hrdE-3bdqA: undetectable 3hrdF-3bdqA: undetectable	3hrdA-3bdqA: 13.27 3hrdE-3bdqA: 13.27 3hrdF-3bdqA: 14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AX8_A_SAMA1474_1 (WBDD)	3bdq	STEROL CARRIER PROTEIN 2-LIKE 2 (Aedes aegypti)	4 / 6	GLN A 48 ASP A 52 GLU A 8 LEU A 49	None	1.22A	4ax8A-3bdqA: undetectable	4ax8A-3bdqA: 11.25

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1M8E_B_H4BB903_1","INDUCIBLE NITRIC OXIDE SYNTHASE","3bdq","STEROL CARRIER PROTEIN 2-LIKE 2","Aedes aegypti",3,"ARG A   0;ILE A  33;TRP A  42","None","1.09A","1m8eB-3bdqA:undetectable","1m8eB-3bdqA:14.42"],["2BDM_A_TMIA503_1","CYTOCHROME P450 2B4","3bdq","STEROL CARRIER PROTEIN 2-LIKE 2","Aedes aegypti",4,"VAL A  51;LEU A  49;VAL A  17;VAL A 104","None;None;PLM A 300 ( 4.9A);PLM A 300 ( 4.9A)","0.91A","2bdmA-3bdqA:undetectable","2bdmA-3bdqA:15.65"],["3DZG_A_NCAA302_0","ADP-RIBOSYL CYCLASE 1","3bdq","STEROL CARRIER PROTEIN 2-LIKE 2","Aedes aegypti",4,"LEU A  67;GLU A  68;ASP A  69;SER A   2","None","1.30A","3dzgA-3bdqA:undetectable","3dzgA-3bdqA:21.60"],["3DZG_B_NCAB302_0","ADP-RIBOSYL CYCLASE 1","3bdq","STEROL CARRIER PROTEIN 2-LIKE 2","Aedes aegypti",4,"LEU A  67;GLU A  68;ASP A  69;SER A   2","None","1.28A","3dzgB-3bdqA:undetectable","3dzgB-3bdqA:21.60"],["3E68_A_H4BA902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","3bdq","STEROL CARRIER PROTEIN 2-LIKE 2","Aedes aegypti",3,"ARG A   0;ILE A  33;TRP A  42","None","1.05A","3e68A-3bdqA:undetectable","3e68A-3bdqA:14.69"],["3E6T_B_H4BB902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","3bdq","STEROL CARRIER PROTEIN 2-LIKE 2","Aedes aegypti",3,"ARG A   0;ILE A  33;TRP A  42","None","1.08A","3e6tB-3bdqA:undetectable","3e6tB-3bdqA:14.69"],["3HRD_E_NIOE5660_1","NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT;NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT;NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT","3bdq","STEROL CARRIER PROTEIN 2-LIKE 2","Aedes aegypti",3,"GLU A   4;GLU A   8;TRP A  42","None","1.09A","3hrdA-3bdqA:undetectable;3hrdE-3bdqA:undetectable;3hrdF-3bdqA:undetectable","3hrdA-3bdqA:13.27;3hrdE-3bdqA:13.27;3hrdF-3bdqA:14.91"],["4AX8_A_SAMA1474_1","WBDD","3bdq","STEROL CARRIER PROTEIN 2-LIKE 2","Aedes aegypti",4,"GLN A  48;ASP A  52;GLU A   8;LEU A  49","None","1.22A","4ax8A-3bdqA:undetectable","4ax8A-3bdqA:11.25"]]