SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bdv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		3 / 3 TRP A  44
ARG A  66
THR A  18
 None
 0.94A 1df7A-3bdvA:
undetectable		 1df7A-3bdvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		5 / 10 LEU A 123
SER A 152
THR A 129
ALA A  87
ALA A  84
 None
 1.27A 1wygA-3bdvA:
undetectable		 1wygA-3bdvA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		4 / 7 ARG A  39
ASP A  29
ALA A 165
ASP A  30
 None
 1.16A 2e5dA-3bdvA:
undetectable
2e5dB-3bdvA:
undetectable		 2e5dA-3bdvA:
16.36
2e5dB-3bdvA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		4 / 7 ASP A  30
ARG A  39
ASP A  29
ALA A 165
 None
 1.16A 2e5dA-3bdvA:
undetectable
2e5dB-3bdvA:
undetectable		 2e5dA-3bdvA:
16.36
2e5dB-3bdvA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		4 / 8 LEU A 137
ALA A 105
SER A  81
HIS A  80
 None
None
CL  A 193 (-3.0A)
None
 0.92A 3kp6A-3bdvA:
undetectable		 3kp6A-3bdvA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		5 / 12 ARG A   9
GLY A 100
ALA A 180
LEU A  17
ILE A  76
 EDO  A 196 (-3.8A)
None
None
None
None
 0.95A 3ku1C-3bdvA:
2.2		 3ku1C-3bdvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		5 / 12 ARG A   9
GLY A 100
ALA A 180
LEU A  17
ILE A  76
 EDO  A 196 (-3.8A)
None
None
None
None
 0.96A 3ku1H-3bdvA:
2.6		 3ku1H-3bdvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		5 / 10 LEU A  21
ILE A  47
ILE A  78
GLY A  79
GLY A  83
 None
 0.92A 4fakA-3bdvA:
undetectable		 4fakA-3bdvA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		3 / 3 ASP A 135
TRP A 150
SER A  81
 None
None
CL  A 193 (-3.0A)
 0.97A 4lrhF-3bdvA:
undetectable		 4lrhF-3bdvA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		3 / 3 VAL A 101
ALA A  99
PHE A 182
 None
 0.90A 4olbA-3bdvA:
5.9		 4olbA-3bdvA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		3 / 3 GLN A  93
HIS A  89
ARG A 117
 None
 1.13A 4qyqB-3bdvA:
undetectable		 4qyqB-3bdvA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		3 / 3 VAL A 101
ALA A  99
PHE A 182
 None
 0.82A 4w5nA-3bdvA:
5.3		 4w5nA-3bdvA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		3 / 3 VAL A 101
ALA A  99
PHE A 182
 None
 0.90A 4z4iA-3bdvA:
5.3		 4z4iA-3bdvA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		3 / 3 VAL A 101
ALA A  99
PHE A 182
 None
 0.89A 5js1A-3bdvA:
undetectable		 5js1A-3bdvA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		4 / 8 GLU A 166
HIS A  80
PHE A  82
LEU A  57
 None
 1.07A 5y2tB-3bdvA:
undetectable		 5y2tB-3bdvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3bdv UNCHARACTERIZED
PROTEIN DUF1234
(Pectobacterium
atrosepticum) 		5 / 7 ALA A 105
ILE A 118
PHE A 112
LEU A  85
CYH A  88
 None
None
CL  A 193 (-4.7A)
None
None
 1.41A 6b5vA-3bdvA:
undetectable
6b5vB-3bdvA:
undetectable		 6b5vA-3bdvA:
18.12
6b5vB-3bdvA:
18.12