SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bdz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 4 THR A 243
LEU A 247
VAL A 250
LEU A 254
 HEM  A 450 (-4.3A)
None
None
None
 0.63A 1fbmD-3bdzA:
undetectable		 1fbmD-3bdzA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 5 THR A 243
LEU A 247
VAL A 250
LEU A 254
 HEM  A 450 (-4.3A)
None
None
None
 0.62A 1fbmE-3bdzA:
undetectable		 1fbmE-3bdzA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 LEU A 340
LEU A 279
LEU A 247
VAL A 250
VAL A 386
 HEM  A 450 (-4.9A)
None
None
None
None
 1.18A 1hrkA-3bdzA:
undetectable		 1hrkA-3bdzA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 10 LEU A 157
ILE A 240
PHE A  86
THR A  83
ILE A 174
 None
 1.38A 1i18A-3bdzA:
undetectable
1i18B-3bdzA:
undetectable		 1i18A-3bdzA:
14.63
1i18B-3bdzA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 10 PHE A  86
THR A  83
ILE A 174
LEU A 157
ILE A 240
 None
 1.39A 1i18A-3bdzA:
undetectable
1i18B-3bdzA:
undetectable		 1i18A-3bdzA:
14.63
1i18B-3bdzA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 PHE A 246
ALA A 242
GLY A 341
LEU A 237
ALA A  91
 HEM  A 450 (-4.9A)
HEM  A 450 (-3.5A)
HEM  A 450 (-4.1A)
MLI  A 500 ( 4.5A)
MLI  A 500 ( 2.9A)
 1.42A 1jipA-3bdzA:
45.7		 1jipA-3bdzA:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 6 LEU A 128
LEU A 121
ILE A 155
GLU A 147
 None
 0.89A 1mt1A-3bdzA:
undetectable
1mt1F-3bdzA:
undetectable		 1mt1A-3bdzA:
8.59
1mt1F-3bdzA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 6 ILE A 155
GLU A 147
LEU A 128
LEU A 121
 None
 0.94A 1mt1B-3bdzA:
undetectable
1mt1C-3bdzA:
undetectable		 1mt1B-3bdzA:
15.86
1mt1C-3bdzA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 4 THR A 243
LEU A 247
VAL A 250
LEU A 254
 HEM  A 450 (-4.3A)
None
None
None
 0.79A 1mz9D-3bdzA:
undetectable		 1mz9D-3bdzA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 LEU A 340
LEU A 279
LEU A 247
VAL A 250
VAL A 386
 HEM  A 450 (-4.9A)
None
None
None
None
 1.22A 2hrcA-3bdzA:
undetectable		 2hrcA-3bdzA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 LEU A 340
LEU A 279
LEU A 247
VAL A 250
VAL A 386
 HEM  A 450 (-4.9A)
None
None
None
None
 1.21A 2po5A-3bdzA:
undetectable		 2po5A-3bdzA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 11 LEU A 340
LEU A 279
LEU A 247
VAL A 250
VAL A 386
 HEM  A 450 (-4.9A)
None
None
None
None
 1.22A 2po5B-3bdzA:
undetectable		 2po5B-3bdzA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 LEU A 340
LEU A 279
LEU A 247
VAL A 250
VAL A 386
 HEM  A 450 (-4.9A)
None
None
None
None
 1.20A 2po7A-3bdzA:
undetectable		 2po7A-3bdzA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 7 LEU A  88
VAL A  76
THR A  77
VAL A 386
 None
 0.92A 2qblA-3bdzA:
48.4		 2qblA-3bdzA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 6 LEU A 340
ARG A 354
ILE A 353
ILE A 155
 HEM  A 450 (-4.9A)
None
HEM  A 450 (-3.8A)
None
 0.84A 2xkwB-3bdzA:
undetectable		 2xkwB-3bdzA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 9 ILE A 361
ALA A 255
LEU A 254
LEU A 278
ALA A 357
 None
 1.08A 3ozvB-3bdzA:
undetectable		 3ozvB-3bdzA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 11 ILE A 148
ALA A 244
ILE A 394
LEU A 144
THR A 243
 None
None
None
None
HEM  A 450 (-4.3A)
 1.32A 3qg2B-3bdzA:
undetectable		 3qg2B-3bdzA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 HIS A  52
VAL A 287
ALA A  48
ALA A  14
SER A   9
 None
HEM  A 450 (-4.8A)
None
None
None
 0.97A 3sudD-3bdzA:
undetectable		 3sudD-3bdzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 5 LEU A 290
ALA A 308
THR A 292
PHE A  71
 None
 1.36A 3vasB-3bdzA:
undetectable		 3vasB-3bdzA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 8 ARG A 280
TYR A 282
GLU A 277
HIS A  28
 None
 1.44A 3zmdA-3bdzA:
undetectable
3zmdB-3bdzA:
undetectable		 3zmdA-3bdzA:
16.88
3zmdB-3bdzA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 5 PHE A 364
PHE A 396
ILE A 394
GLY A 138
 None
 0.94A 4ejjC-3bdzA:
29.8		 4ejjC-3bdzA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 ASP A 208
LEU A 159
LEU A 348
PHE A 231
ALA A 194
 None
None
HEM  A 450 (-4.1A)
None
None
 1.24A 4retA-3bdzA:
undetectable		 4retA-3bdzA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 SER A 248
LEU A 373
ASP A  24
ARG A 317
GLU A  32
 None
 1.41A 4zjlD-3bdzA:
0.5		 4zjlD-3bdzA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 THR A  12
VAL A  54
ALA A  33
LEU A  34
ALA A  38
 None
 0.96A 5kpcA-3bdzA:
undetectable		 5kpcA-3bdzA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 7 LEU A 237
ASP A 241
ALA A 244
LEU A 247
 MLI  A 500 ( 4.5A)
None
None
None
 1.07A 5nwvA-3bdzA:
undetectable		 5nwvA-3bdzA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3bdz P450CIN
(Citrobacter
braakii) 		3 / 3 HIS A 193
GLU A 189
TRP A 170
 None
 0.93A 5odiD-3bdzA:
undetectable		 5odiD-3bdzA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3bdz P450CIN
(Citrobacter
braakii) 		3 / 3 HIS A 193
GLU A 189
TRP A 170
 None
 0.91A 5odqD-3bdzA:
undetectable		 5odqD-3bdzA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3bdz P450CIN
(Citrobacter
braakii) 		3 / 3 HIS A 193
GLU A 189
TRP A 170
 None
 0.95A 5odrD-3bdzA:
undetectable		 5odrD-3bdzA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3bdz P450CIN
(Citrobacter
braakii) 		4 / 8 ILE A 234
LEU A 235
LEU A 157
MET A  90
 HEM  A 450 (-4.7A)
None
None
HEM  A 450 (-4.6A)
 0.98A 5u4sB-3bdzA:
undetectable		 5u4sB-3bdzA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 12 LEU A 279
ARG A 354
ILE A 353
GLY A 349
VAL A 386
 None
None
HEM  A 450 (-3.8A)
HEM  A 450 (-3.6A)
None
 0.99A 5ycnA-3bdzA:
undetectable		 5ycnA-3bdzA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6L_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 9 ILE A 129
ALA A 360
LEU A 365
ILE A 394
PRO A 397
 None
 1.29A 5z6lA-3bdzA:
undetectable		 5z6lA-3bdzA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 3bdz P450CIN
(Citrobacter
braakii) 		5 / 11 PRO A 393
GLU A 378
PRO A  23
PRO A  27
ALA A  29
 None
 1.37A 6bm5A-3bdzA:
undetectable		 6bm5A-3bdzA:
24.39