SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3be4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3be4 ADENYLATE KINASE
(Cryptosporidium
parvum) 		3 / 3 SER A  16
GLY A  15
ARG A  93
 AP5  A 219 (-3.7A)
AP5  A 219 (-3.3A)
AP5  A 219 (-2.6A)
 0.62A 1t9wA-3be4A:
undetectable		 1t9wA-3be4A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AXN_A_EDTA737_0
(6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE 3
(6PF-2-K/FRU-
2,6-P2ASE
BRAIN/PLACENTA-TYPE
ISOZYME) (IPFK-2)
[INCLUDES: 6-
PHOSPHOFRUCTO-2-KINA
SE (EC 2.7.1.105)
FRUCTOSE-2,6-BISPHO
SPHATASE (EC
3.1.3.46)])		 3be4 ADENYLATE KINASE
(Cryptosporidium
parvum) 		5 / 12 PRO A  14
LYS A  18
GLY A  37
ARG A  41
ARG A 176
 AP5  A 219 (-4.3A)
AP5  A 219 (-2.9A)
AP5  A 219 (-3.4A)
AP5  A 219 (-3.3A)
AP5  A 219 (-3.4A)
 1.12A 2axnA-3be4A:
12.6		 2axnA-3be4A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 3be4 ADENYLATE KINASE
(Cryptosporidium
parvum) 		3 / 3 GLN A 183
THR A 184
LEU A  70
 None
 0.76A 3ondA-3be4A:
undetectable		 3ondA-3be4A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 3be4 ADENYLATE KINASE
(Cryptosporidium
parvum) 		3 / 3 GLN A 183
THR A 184
LEU A  70
 None
 0.75A 3ondB-3be4A:
undetectable		 3ondB-3be4A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3be4 ADENYLATE KINASE
(Cryptosporidium
parvum) 		4 / 8 SER A  60
ARG A  93
VAL A 175
PHE A  63
 None
AP5  A 219 (-2.6A)
None
AP5  A 219 ( 4.7A)
 1.32A 5uo7A-3be4A:
undetectable
5uo7B-3be4A:
undetectable		 5uo7A-3be4A:
18.25
5uo7B-3be4A:
18.25