SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3be7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 8 GLY A 313
GLU A 242
SER A 263
PHE A 353
 None
 0.82A 1ax9A-3be7A:
undetectable		 1ax9A-3be7A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 8 GLY A 313
GLU A 242
SER A 263
PHE A 353
 None
 0.96A 1ax9A-3be7A:
undetectable		 1ax9A-3be7A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 5 HIS A  62
HIS A 142
HIS A 223
HIS A 243
ASP A 315
 None
 1.24A 1e9yB-3be7A:
19.5		 1e9yB-3be7A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 6 HIS A  62
HIS A  64
HIS A 223
HIS A 243
ASP A 315
 None
 0.83A 1fweC-3be7A:
12.1		 1fweC-3be7A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 6 HIS A  62
HIS A 142
HIS A 223
HIS A 243
ASP A 315
 None
 1.21A 1fweC-3be7A:
12.1		 1fweC-3be7A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 4 ALA A 222
VAL A 220
ALA A 221
HIS A  62
 None
 1.26A 1q23F-3be7A:
undetectable		 1q23F-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 4 ALA A 222
VAL A 220
ALA A 221
HIS A  62
 None
 1.25A 1q23K-3be7A:
undetectable		 1q23K-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 LEU A 180
ASP A 112
HIS A  64
GLY A 106
HIS A  62
 None
 1.09A 1zz1C-3be7A:
undetectable		 1zz1C-3be7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 7 GLY A 313
GLU A 242
SER A 263
PHE A 353
 None
 0.92A 2ackA-3be7A:
undetectable		 2ackA-3be7A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 9 THR A  94
ILE A  65
GLY A 126
ARG A 116
ILE A 119
 None
 1.34A 2y7wA-3be7A:
undetectable		 2y7wA-3be7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 LEU A 291
GLU A 283
LEU A 273
ILE A 272
SER A 269
 None
 1.24A 2ydoA-3be7A:
undetectable		 2ydoA-3be7A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 6 ILE A 355
ILE A  16
LEU A 130
MET A  59
 None
 0.93A 3adsA-3be7A:
undetectable		 3adsA-3be7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 7 ILE A 355
ILE A  16
LEU A 130
MET A  59
 None
 0.90A 3adxA-3be7A:
undetectable		 3adxA-3be7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_D_TMQD614_1
(DHFR-TS)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 10 VAL A  46
ALA A  44
ILE A 369
ILE A  47
THR A  41
 None
 1.23A 3clbD-3be7A:
undetectable		 3clbD-3be7A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 GLU A 157
SER A 132
VAL A 113
TYR A 110
ASN A 173
 None
 1.41A 3g0bB-3be7A:
undetectable		 3g0bB-3be7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 GLU A 157
SER A 132
VAL A 113
TYR A 110
ASN A 173
 None
 1.39A 3g0bC-3be7A:
undetectable		 3g0bC-3be7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 GLU A 157
SER A 132
VAL A 113
TYR A 110
ASN A 173
 None
 1.40A 3g0bD-3be7A:
undetectable		 3g0bD-3be7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 10 VAL A  46
ALA A  44
ILE A 369
ILE A  47
THR A  41
 None
 1.25A 3hbbD-3be7A:
undetectable		 3hbbD-3be7A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 6 ASN A 379
ILE A 380
GLU A 374
ASN A 375
 None
 1.34A 3kp6A-3be7A:
0.0
3kp6B-3be7A:
undetectable		 3kp6A-3be7A:
21.29
3kp6B-3be7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 ASP A 253
ARG A 297
ILE A 266
ILE A 230
ALA A 255
 None
 1.21A 3ohtA-3be7A:
undetectable
3ohtB-3be7A:
undetectable		 3ohtA-3be7A:
20.96
3ohtB-3be7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 11 ALA A 325
PHE A 328
ILE A  55
ALA A  97
VAL A 102
 None
 1.15A 3rukD-3be7A:
undetectable		 3rukD-3be7A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 7 GLY A 317
ASP A 320
ASP A 323
ILE A 272
 GOL  A 502 (-3.6A)
None
None
None
 0.64A 3t3cA-3be7A:
undetectable		 3t3cA-3be7A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 9 LEU A 291
ILE A 281
ILE A 318
GLU A 283
VAL A 189
 None
 1.18A 3tmzA-3be7A:
undetectable		 3tmzA-3be7A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.44A 3u9fB-3be7A:
undetectable
3u9fC-3be7A:
undetectable		 3u9fB-3be7A:
19.02
3u9fC-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_C_CLMC221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 11 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.46A 3u9fA-3be7A:
0.0
3u9fC-3be7A:
0.0		 3u9fA-3be7A:
19.02
3u9fC-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 10 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.48A 3u9fE-3be7A:
undetectable		 3u9fE-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.46A 3u9fH-3be7A:
undetectable
3u9fI-3be7A:
undetectable		 3u9fH-3be7A:
19.02
3u9fI-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 10 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.50A 3u9fI-3be7A:
undetectable		 3u9fI-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 10 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.47A 3u9fK-3be7A:
undetectable		 3u9fK-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.48A 3u9fJ-3be7A:
undetectable
3u9fL-3be7A:
undetectable		 3u9fJ-3be7A:
19.02
3u9fL-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 11 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.44A 3u9fM-3be7A:
undetectable
3u9fO-3be7A:
undetectable		 3u9fM-3be7A:
19.02
3u9fO-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 9 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.47A 3u9fP-3be7A:
undetectable		 3u9fP-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 THR A 349
SER A 345
SER A  61
VAL A 268
PHE A 319
 None
 1.38A 3u9fP-3be7A:
undetectable
3u9fS-3be7A:
undetectable		 3u9fP-3be7A:
19.02
3u9fS-3be7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 8 ILE A 318
ILE A 272
GLN A 296
GLY A 293
 None
 0.82A 4acaC-3be7A:
3.4		 4acaC-3be7A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 8 SER A 285
ASN A 287
ARG A 290
GLY A 280
 None
 1.00A 4af0A-3be7A:
6.2		 4af0A-3be7A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 5 HIS A  62
HIS A 142
HIS A 223
HIS A 243
ASP A 315
 None
 1.24A 4h9mA-3be7A:
21.2		 4h9mA-3be7A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 8 LEU A 262
ILE A 266
GLN A 296
VAL A 292
 None
 0.93A 4ma7A-3be7A:
undetectable		 4ma7A-3be7A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		6 / 12 ARG A 103
LEU A 180
ALA A 213
ILE A 209
GLY A 237
ILE A 181
 None
 1.30A 4q1xB-3be7A:
undetectable		 4q1xB-3be7A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		3 / 3 TYR A 110
GLY A 133
PRO A 134
 None
 0.70A 4qwpA-3be7A:
undetectable		 4qwpA-3be7A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 6 HIS A  62
HIS A  64
HIS A 223
HIS A 243
ASP A 315
 None
 0.76A 4ubpC-3be7A:
19.2		 4ubpC-3be7A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 7 GLY A 317
ASP A 320
ASP A 323
ILE A 272
 GOL  A 502 (-3.6A)
None
None
None
 0.64A 5kqyB-3be7A:
undetectable		 5kqyB-3be7A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 8 GLY A 317
ASP A 320
ASP A 323
ILE A 272
 GOL  A 502 (-3.6A)
None
None
None
 0.56A 5kr1B-3be7A:
undetectable		 5kr1B-3be7A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 9 ILE A 247
VAL A 241
THR A 260
ASN A 258
ILE A 234
 None
 1.38A 5lg3B-3be7A:
undetectable		 5lg3B-3be7A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 9 ILE A 247
VAL A 241
THR A 260
ASN A 258
ILE A 234
 None
 1.40A 5lg3C-3be7A:
undetectable		 5lg3C-3be7A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 9 ILE A 247
VAL A 241
THR A 260
ASN A 258
ILE A 234
 None
 1.38A 5lg3D-3be7A:
undetectable		 5lg3D-3be7A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		5 / 12 PHE A 328
GLY A  57
GLY A  98
ASP A 366
ILE A 358
 None
 1.11A 6b3aA-3be7A:
2.5		 6b3aA-3be7A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 8 ILE A 347
THR A 346
THR A 101
SER A  61
 None
 1.02A 6c06C-3be7A:
undetectable		 6c06C-3be7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3be7 ZN-DEPENDENT
ARGININE
CARBOXYPEPTIDASE
(unidentified) 		4 / 8 ASP A  69
GLY A 313
SER A 263
VAL A 105
 GOL  A 502 (-2.8A)
None
None
None
 1.05A 6giqL-3be7A:
undetectable
6giqP-3be7A:
undetectable
6giqT-3be7A:
undetectable		 6giqL-3be7A:
22.48
6giqP-3be7A:
19.90
6giqT-3be7A:
11.17