SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bed'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 3bed PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		5 / 10 ALA A  97
ALA A 100
LEU A 111
LEU A   5
LEU A  18
 None
 0.93A 2bxgB-3bedA:
undetectable		 2bxgB-3bedA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 3bed PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		4 / 8 LEU A   5
ALA A 112
LEU A 111
ILE A  33
 None
 0.91A 3cldB-3bedA:
undetectable		 3cldB-3bedA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 3bed PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		5 / 10 ALA A  14
ILE A  33
ILE A  52
LEU A  49
ILE A   6
 None
 1.18A 4dtaA-3bedA:
undetectable		 4dtaA-3bedA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 3bed PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		5 / 10 ILE A  33
THR A  61
LEU A  86
ILE A   6
THR A  17
 None
 1.34A 4km0A-3bedA:
undetectable		 4km0A-3bedA:
21.56