SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3bem PUTATIVE NAD(P)H
NITROREDUCTASE YDFN
(Bacillus
subtilis) 		5 / 9 GLY A 158
VAL A  72
GLN A  55
ASN A  66
GLY A  67
 FMN  A 300 (-3.6A)
None
None
None
None
 1.29A 3kmoA-3bemA:
undetectable		 3kmoA-3bemA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bem PUTATIVE NAD(P)H
NITROREDUCTASE YDFN
(Bacillus
subtilis) 		4 / 5 ARG A 166
LEU A  61
ILE A 157
PHE A 159
 None
None
FMN  A 300 (-4.0A)
None
 1.22A 3ln1D-3bemA:
undetectable		 3ln1D-3bemA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3bem PUTATIVE NAD(P)H
NITROREDUCTASE YDFN
(Bacillus
subtilis) 		5 / 6 ALA A 135
THR A  47
VAL A  80
TYR A  49
HIS A  46
 None
 1.41A 5ecoA-3bemA:
undetectable		 5ecoA-3bemA:
16.15