SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3beo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 6 ILE A 173
GLU A 122
LEU A 125
LEU A 161
 None
 1.04A 1mt1B-3beoA:
undetectable
1mt1C-3beoA:
undetectable		 1mt1B-3beoA:
16.27
1mt1C-3beoA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 THR A 154
GLY A 124
GLU A 122
GLU A 291
ASN A 160
 None
 1.36A 1odiB-3beoA:
undetectable		 1odiB-3beoA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 THR A 154
GLY A 124
GLU A 122
GLU A 291
ASN A 160
 None
 1.35A 1odiD-3beoA:
undetectable		 1odiD-3beoA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 THR A 154
GLY A 124
GLU A 122
GLU A 291
ASN A 160
 None
 1.34A 1odiE-3beoA:
undetectable		 1odiE-3beoA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 THR A 154
GLY A 124
GLU A 122
GLU A 291
ASN A 160
 None
 1.36A 1odiF-3beoA:
2.3		 1odiF-3beoA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 6 LEU A 109
PHE A 112
ALA A 111
LEU A  80
 None
 0.89A 1ukbA-3beoA:
7.5		 1ukbA-3beoA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 LEU A 366
HIS A  30
LYS A  33
 None
 0.89A 1y7iA-3beoA:
7.7		 1y7iA-3beoA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 8 VAL A  24
VAL A  38
LEU A  25
ASP A  60
 None
 0.96A 2ddwA-3beoA:
3.7		 2ddwA-3beoA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 GLU A  26
VAL A 362
ILE A 365
LEU A 366
ILE A  37
 None
 1.16A 2dg9A-3beoA:
undetectable		 2dg9A-3beoA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 ILE A 106
GLU A  16
THR A  39
THR A 103
GLY A  79
 None
 1.40A 2fn1B-3beoA:
undetectable		 2fn1B-3beoA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 6 PRO A 299
LEU A 301
LYS A 319
GLY A 312
 None
 1.05A 2hs2B-3beoA:
undetectable		 2hs2B-3beoA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2N27_A_4DYA205_1
(CALMODULIN)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 ILE A  34
MET A  20
LEU A  63
VAL A  86
MET A  87
 None
 1.47A 2n27A-3beoA:
0.0		 2n27A-3beoA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 4 VAL A 302
THR A 284
VAL A 289
GLY A 288
 None
None
None
UDP  A1081 (-3.7A)
 1.18A 2p2fB-3beoA:
2.5		 2p2fB-3beoA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 PRO A 294
GLY A 312
TYR A 352
 None
 0.72A 2vouA-3beoA:
2.4		 2vouA-3beoA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 PRO A 294
GLY A 312
TYR A 352
 None
 0.64A 2vouB-3beoA:
3.2		 2vouB-3beoA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 PRO A 294
GLY A 312
TYR A 352
 None
 0.64A 2vouC-3beoA:
4.0		 2vouC-3beoA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 12 ASN A 213
THR A 284
VAL A 302
LEU A 320
SER A 132
 None
 1.45A 2xrlA-3beoA:
undetectable		 2xrlA-3beoA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 7 GLU A 136
ARG A 140
GLU A 212
SER A 132
 UD1  A 372 (-3.6A)
None
None
None
 1.24A 2zt7A-3beoA:
2.3		 2zt7A-3beoA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 ASP A  49
LEU A  48
GLN A  70
 None
None
UD1  A 372 (-3.7A)
 0.73A 3g4lA-3beoA:
undetectable		 3g4lA-3beoA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 ARG A  69
ASP A  74
ASP A  68
 None
None
UD1  A 372 (-4.7A)
 0.70A 3jayA-3beoA:
undetectable		 3jayA-3beoA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 6 ASN A 220
MET A 221
ILE A 328
ASN A 213
 None
 1.43A 3kp6A-3beoA:
undetectable
3kp6B-3beoA:
undetectable		 3kp6A-3beoA:
17.66
3kp6B-3beoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 GLU A 292
LEU A 182
LEU A  25
 UDP  A1081 (-2.7A)
None
None
 0.76A 3ohtA-3beoA:
undetectable		 3ohtA-3beoA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 12 ALA A 224
LEU A 228
LEU A 283
LEU A 301
MET A 345
 None
 1.00A 3uvvA-3beoA:
undetectable		 3uvvA-3beoA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 12 ALA A 224
LEU A 283
LEU A 301
ILE A 328
MET A 345
 None
 1.07A 3uvvA-3beoA:
undetectable		 3uvvA-3beoA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 ARG A 126
MET A 138
ARG A 140
 None
 1.21A 3uvvA-3beoA:
undetectable		 3uvvA-3beoA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 LEU A 283
MET A 221
ASP A 324
 None
 0.92A 3v5wA-3beoA:
undetectable		 3v5wA-3beoA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 ARG A 304
ARG A 140
ASP A 129
 None
 0.91A 3wipG-3beoA:
undetectable
3wipH-3beoA:
undetectable		 3wipG-3beoA:
21.18
3wipH-3beoA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 8 ILE A 171
PHE A 151
SER A 108
GLY A 119
 None
 0.75A 4acaC-3beoA:
7.4		 4acaC-3beoA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 8 ILE A 171
PHE A 151
SER A 108
GLY A 119
 None
 0.79A 4acbC-3beoA:
7.7		 4acbC-3beoA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 ASP A 100
ARG A 304
PRO A 133
 None
 1.03A 4wanC-3beoA:
undetectable		 4wanC-3beoA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 12 LEU A  23
GLY A 175
GLY A 353
PRO A 351
GLU A 291
 None
 1.16A 4x61A-3beoA:
3.9		 4x61A-3beoA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 LEU A 255
LEU A 336
LEU A 301
LEU A 303
ILE A 328
 None
 1.06A 4zowA-3beoA:
undetectable		 4zowA-3beoA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 9 SER A 295
GLY A 297
ALA A 276
VAL A 298
GLU A 292
 None
None
None
None
UDP  A1081 (-2.7A)
 1.50A 5i3cA-3beoA:
undetectable		 5i3cA-3beoA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 11 THR A 207
ALA A 208
VAL A 300
GLY A 288
GLY A 287
 UDP  A1081 ( 4.9A)
None
None
UDP  A1081 (-3.7A)
UDP  A1081 (-3.7A)
 0.82A 5lf7K-3beoA:
undetectable
5lf7L-3beoA:
undetectable		 5lf7K-3beoA:
18.49
5lf7L-3beoA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		4 / 5 VAL A  86
THR A  39
ASP A  62
LEU A  63
 None
 1.35A 5m0iB-3beoA:
undetectable		 5m0iB-3beoA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		3 / 3 SER A 346
HIS A 342
TYR A 280
 None
 0.99A 5y2tA-3beoA:
undetectable		 5y2tA-3beoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE
(Bacillus
anthracis) 		5 / 12 VAL A 362
LEU A  27
GLU A 363
LEU A  96
LEU A  23
 None
 1.14A 6f6iA-3beoA:
undetectable
6f6iB-3beoA:
undetectable		 6f6iA-3beoA:
13.56
6f6iB-3beoA:
13.58