SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bf4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JTV_A_TESA500_1 (17 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1)	3bf4	ETHYL TERT-BUTYL ETHER DEGRADATION ETHD PROTEIN (Cupriavidus pinatubonensis)	4 / 8	VAL A 4 TYR A 21 HIS A 25 VAL A 29	None EDO A 109 (-4.5A) EDO A 109 (-4.3A) None	0.93A	1jtvA-3bf4A: undetectable	1jtvA-3bf4A: 16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_A_ACTA860_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3bf4	ETHYL TERT-BUTYL ETHER DEGRADATION ETHD PROTEIN (Cupriavidus pinatubonensis)	4 / 6	GLY A 0 GLN A -1 ALA A 68 SER A 67	None	0.97A	1p6kA-3bf4A: undetectable	1p6kA-3bf4A: 15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QL8_B_BEZB143_0 (PUTATIVE REDOX PROTEIN)	3bf4	ETHYL TERT-BUTYL ETHER DEGRADATION ETHD PROTEIN (Cupriavidus pinatubonensis)	4 / 6	TYR A 20 THR A 90 ALA A 87 ARG A 15	None	1.44A	2ql8A-3bf4A: 2.6 2ql8B-3bf4A: 2.5	2ql8A-3bf4A: 25.16 2ql8B-3bf4A: 25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NKN_A_LOCA201_2 (NEUTROPHIL GELATINASE-ASSOCIATE D LIPOCALIN)	3bf4	ETHYL TERT-BUTYL ETHER DEGRADATION ETHD PROTEIN (Cupriavidus pinatubonensis)	3 / 3	VAL A 4 LYS A 30 MET A 28	None	0.83A	5nknA-3bf4A: undetectable	5nknA-3bf4A: 16.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JTV_A_TESA500_1","17 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1","3bf4","ETHYL TERT-BUTYL ETHER DEGRADATION ETHD PROTEIN","Cupriavidus pinatubonensis",4,"VAL A   4;TYR A  21;HIS A  25;VAL A  29","None;EDO A 109 (-4.5A);EDO A 109 (-4.3A);None","0.93A","1jtvA-3bf4A:undetectable","1jtvA-3bf4A:16.41"],["1P6K_A_ACTA860_0","NITRIC-OXIDE SYNTHASE, BRAIN","3bf4","ETHYL TERT-BUTYL ETHER DEGRADATION ETHD PROTEIN","Cupriavidus pinatubonensis",4,"GLY A   0;GLN A  -1;ALA A  68;SER A  67","None","0.97A","1p6kA-3bf4A:undetectable","1p6kA-3bf4A:15.59"],["2QL8_B_BEZB143_0","PUTATIVE REDOX PROTEIN","3bf4","ETHYL TERT-BUTYL ETHER DEGRADATION ETHD PROTEIN","Cupriavidus pinatubonensis",4,"TYR A  20;THR A  90;ALA A  87;ARG A  15","None","1.44A","2ql8A-3bf4A:2.6;2ql8B-3bf4A:2.5","2ql8A-3bf4A:25.16;2ql8B-3bf4A:25.16"],["5NKN_A_LOCA201_2","NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN","3bf4","ETHYL TERT-BUTYL ETHER DEGRADATION ETHD PROTEIN","Cupriavidus pinatubonensis",3,"VAL A   4;LYS A  30;MET A  28","None","0.83A","5nknA-3bf4A:undetectable","5nknA-3bf4A:16.80"]]