SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bf5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		6 / 12 THR A 196
GLY A 198
ALA A 225
GLY A 226
ALA A 254
ILE A 258
 PGO  A 290 (-4.0A)
PGO  A 290 (-3.8A)
PGO  A 290 ( 4.1A)
PGO  A 290 ( 4.6A)
PGO  A 290 ( 3.8A)
None
 0.76A 1bx4A-3bf5A:
21.1		 1bx4A-3bf5A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 10 THR A 196
GLY A 198
ALA A 225
ALA A 254
ILE A 258
 PGO  A 290 (-4.0A)
PGO  A 290 (-3.8A)
PGO  A 290 ( 4.1A)
PGO  A 290 ( 3.8A)
None
 0.66A 1likA-3bf5A:
23.8		 1likA-3bf5A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 5 LEU A  10
GLY A  41
ILE A  72
PHE A  36
 None
 0.96A 1xf1A-3bf5A:
undetectable		 1xf1A-3bf5A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 7 HIS A   9
ASP A  13
GLY A  37
GLY A  38
ASN A  42
 PGO  A 288 ( 4.9A)
None
None
None
None
 0.72A 2c49B-3bf5A:
31.2		 2c49B-3bf5A:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 GLY A  37
GLY A  38
ASN A  42
GLY A 224
ASP A 227
 None
 0.44A 2pkkA-3bf5A:
27.8		 2pkkA-3bf5A:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 GLY A  37
GLY A  38
ASN A  42
GLY A 224
ASP A 227
 None
 0.44A 2pkmA-3bf5A:
28.0		 2pkmA-3bf5A:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 7 GLY A  41
ILE A  77
THR A  79
LEU A  10
 None
 0.90A 2xrhA-3bf5A:
undetectable		 2xrhA-3bf5A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 6 PRO A  91
GLY A  37
GLY A  41
GLY A  38
GLY A   8
 None
 1.23A 3bogA-3bf5A:
undetectable
3bogC-3bf5A:
undetectable		 3bogA-3bf5A:
undetectable
3bogC-3bf5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 6 PHE A 180
TYR A 177
THR A 193
VAL A 191
 None
 1.23A 3lb3A-3bf5A:
undetectable		 3lb3A-3bf5A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 6 PHE A 180
TYR A 177
THR A 193
VAL A 191
 None
 1.33A 3lb3B-3bf5A:
undetectable		 3lb3B-3bf5A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 GLY A  37
GLY A  38
ASN A  42
GLY A 224
ASP A 227
 None
 0.56A 3uboA-3bf5A:
22.5		 3uboA-3bf5A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 GLY A  37
GLY A  38
ASN A  42
GLY A 224
ASP A 227
 None
 0.56A 4e3aB-3bf5A:
23.5		 4e3aB-3bf5A:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 LEU A  69
LEU A  10
ASN A  11
THR A 129
ALA A 110
 None
 1.16A 4x1kA-3bf5A:
3.1
4x1kB-3bf5A:
2.3		 4x1kA-3bf5A:
20.35
4x1kB-3bf5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 6 PHE A 205
SER A 170
HIS A 164
PRO A 189
 None
 1.22A 5dzka-3bf5A:
undetectable
5dzko-3bf5A:
undetectable		 5dzka-3bf5A:
21.59
5dzko-3bf5A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		3 / 3 MET A 106
HIS A   9
GLY A 109
 None
PGO  A 288 ( 4.9A)
None
 0.86A 5gwzB-3bf5A:
undetectable		 5gwzB-3bf5A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 GLY A 198
ALA A 225
GLY A 226
ALA A 254
ILE A 258
 PGO  A 290 (-3.8A)
PGO  A 290 ( 4.1A)
PGO  A 290 ( 4.6A)
PGO  A 290 ( 3.8A)
None
 0.57A 5kb6A-3bf5A:
22.4		 5kb6A-3bf5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 THR A 196
GLY A 198
ALA A 225
GLY A 226
ALA A 254
 PGO  A 290 (-4.0A)
PGO  A 290 (-3.8A)
PGO  A 290 ( 4.1A)
PGO  A 290 ( 4.6A)
PGO  A 290 ( 3.8A)
 0.51A 5kb6A-3bf5A:
22.4		 5kb6A-3bf5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 GLY A 198
ALA A 225
GLY A 226
ALA A 254
ILE A 258
 PGO  A 290 (-3.8A)
PGO  A 290 ( 4.1A)
PGO  A 290 ( 4.6A)
PGO  A 290 ( 3.8A)
None
 0.54A 5kb6B-3bf5A:
22.6		 5kb6B-3bf5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 THR A 196
GLY A 198
ALA A 225
GLY A 226
ALA A 254
 PGO  A 290 (-4.0A)
PGO  A 290 (-3.8A)
PGO  A 290 ( 4.1A)
PGO  A 290 ( 4.6A)
PGO  A 290 ( 3.8A)
 0.50A 5kb6B-3bf5A:
22.6		 5kb6B-3bf5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 6 PHE A  36
LEU A  10
ARG A  35
GLY A  38
 None
 1.04A 5o4yF-3bf5A:
undetectable		 5o4yF-3bf5A:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 8 TYR A  68
ILE A  72
ALA A  40
ASP A  13
 None
 0.99A 6hu9a-3bf5A:
undetectable
6hu9e-3bf5A:
undetectable		 6hu9a-3bf5A:
19.96
6hu9e-3bf5A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3bf5 RIBOKINASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 6 TYR A  68
ILE A  72
ALA A  40
ASP A  13
 None
 1.04A 6hu9m-3bf5A:
0.7
6hu9q-3bf5A:
undetectable		 6hu9m-3bf5A:
19.96
6hu9q-3bf5A:
18.95