SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bfg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		6 / 12 SER A  70
LYS A  73
SER A 130
ASN A 132
LYS A 234
GLY A 236
 MER  A 301 (-1.3A)
MER  A 301 ( 3.8A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
 0.39A 1ghmA-3bfgA:
38.4		 1ghmA-3bfgA:
34.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 6 ASN A 136
ASN A 170
ASN A 104
THR A 103
 None
MER  A 301 (-2.6A)
MER  A 301 ( 4.1A)
None
 1.25A 1h7xA-3bfgA:
undetectable		 1h7xA-3bfgA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 6 ASN A 136
ASN A 170
ASN A 104
THR A 103
 None
MER  A 301 (-2.6A)
MER  A 301 ( 4.1A)
None
 1.22A 1h7xB-3bfgA:
undetectable		 1h7xB-3bfgA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 6 ASN A 136
ASN A 170
ASN A 104
THR A 103
 None
MER  A 301 (-2.6A)
MER  A 301 ( 4.1A)
None
 1.24A 1h7xC-3bfgA:
undetectable		 1h7xC-3bfgA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 6 ASN A 136
ASN A 170
ASN A 104
THR A 103
 None
MER  A 301 (-2.6A)
MER  A 301 ( 4.1A)
None
 1.22A 1h7xD-3bfgA:
undetectable		 1h7xD-3bfgA:
13.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		10 / 12 SER A  70
LYS A  73
ASN A 104
SER A 130
ASN A 132
GLU A 166
THR A 216
LYS A 234
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.3A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.48A 1i2wA-3bfgA:
41.5		 1i2wA-3bfgA:
42.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		9 / 12 SER A  70
LYS A  73
ASN A 104
SER A 130
ASN A 132
GLU A 166
THR A 216
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.3A)
MER  A 301 (-3.6A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.50A 1i2wB-3bfgA:
41.7		 1i2wB-3bfgA:
42.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 LEU A 138
ALA A 134
SER A  72
THR A  76
VAL A  80
 None
 0.98A 1ictA-3bfgA:
undetectable
1ictC-3bfgA:
undetectable		 1ictA-3bfgA:
20.23
1ictC-3bfgA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 ALA A 237
VAL A 278
LEU A 279
ALA A 280
ALA A 223
 MER  A 301 (-4.2A)
None
None
None
None
 1.08A 1jinA-3bfgA:
undetectable		 1jinA-3bfgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 8 MET A  75
PHE A 160
SER A 154
ILE A 155
 None
 1.17A 1pnlA-3bfgA:
undetectable
1pnlB-3bfgA:
undetectable		 1pnlA-3bfgA:
24.06
1pnlB-3bfgA:
18.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		11 / 12 SER A  70
LYS A  73
ASN A 104
SER A 130
ASN A 132
GLU A 166
ASN A 170
THR A 216
LYS A 234
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.3A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
None
 0.39A 1ymxA-3bfgA:
46.9		 1ymxA-3bfgA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		10 / 12 SER A  70
LYS A  73
ASN A 104
SER A 130
ASN A 132
GLU A 166
ASN A 170
LYS A 234
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.3A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
None
 0.39A 1ymxB-3bfgA:
47.1		 1ymxB-3bfgA:
75.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 12 THR A 194
ASP A 246
LEU A 127
LEU A 211
GLY A 232
 None
 1.48A 2zj0C-3bfgA:
undetectable		 2zj0C-3bfgA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 8 ILE A 247
SER A 130
TYR A 264
SER A  72
 None
MER  A 301 (-2.6A)
None
None
 0.95A 2zw9B-3bfgA:
undetectable		 2zw9B-3bfgA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 12 LEU A 142
GLY A 146
GLY A 144
ALA A 150
THR A 149
 None
 1.02A 3dh0B-3bfgA:
undetectable		 3dh0B-3bfgA:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 LYS A  73
ASN A 104
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
 MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
 0.44A 3hlwA-3bfgA:
46.5		 3hlwA-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 ASN A 104
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.43A 3hlwB-3bfgA:
46.9		 3hlwB-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 LYS A  73
ASN A 104
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.50A 3huoA-3bfgA:
46.7		 3huoA-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		6 / 6 THR A  51
ARG A 191
LEU A 195
GLY A 196
ALA A 257
PRO A 258
 None
 0.28A 3huoA-3bfgA:
46.7		 3huoA-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 LYS A  73
ASN A 104
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ASP A 240
 MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
None
 0.44A 3huoB-3bfgA:
46.8		 3huoB-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.69A 3ny4A-3bfgA:
40.5		 3ny4A-3bfgA:
46.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 8 LEU A 195
ARG A 204
ALA A 205
TRP A 251
PRO A 258
 None
 0.81A 3ny4A-3bfgA:
40.5		 3ny4A-3bfgA:
46.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 10 THR A 159
GLY A  45
TYR A 264
ALA A 185
LYS A 188
 None
 1.30A 3pp7B-3bfgA:
undetectable		 3pp7B-3bfgA:
20.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 LYS A  73
ASN A 104
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ASP A 240
 MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
None
 0.53A 3q07A-3bfgA:
46.5		 3q07A-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		6 / 12 LYS A  73
SER A 130
THR A 171
ASN A 170
LYS A 234
GLY A 236
 MER  A 301 ( 3.8A)
MER  A 301 (-2.6A)
None
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
 1.44A 3q07A-3bfgA:
46.5		 3q07A-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 LYS A  73
ASN A 104
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ASP A 240
 MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
None
 0.43A 3q07B-3bfgA:
46.8		 3q07B-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		6 / 12 LYS A  73
SER A 130
THR A 171
ASN A 170
LYS A 234
GLY A 236
 MER  A 301 ( 3.8A)
MER  A 301 (-2.6A)
None
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
 1.47A 3q07B-3bfgA:
46.8		 3q07B-3bfgA:
74.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 SER A  70
ASN A 104
SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.49A 3sh8A-3bfgA:
40.2		 3sh8A-3bfgA:
43.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 SER A  70
LYS A  73
ASN A 104
SER A 130
ASN A 132
LYS A 234
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.55A 3sh8B-3bfgA:
40.0		 3sh8B-3bfgA:
43.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 LYS A  73
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 MER  A 301 ( 3.8A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.49A 4euzA-3bfgA:
42.7		 4euzA-3bfgA:
51.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		6 / 10 SER A 130
ASN A 132
LYS A 234
THR A 235
GLY A 236
ALA A 237
 MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.52A 4fh2A-3bfgA:
36.0		 4fh2A-3bfgA:
40.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 12 LEU A 122
GLN A  83
ALA A  79
GLY A 143
LEU A 142
 None
 1.03A 4j7xB-3bfgA:
undetectable		 4j7xB-3bfgA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 12 LEU A 122
GLN A  83
ALA A  79
GLY A 144
LEU A 142
 None
 1.07A 4j7xB-3bfgA:
undetectable		 4j7xB-3bfgA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 6 ARG A 161
ASP A 176
ASP A 163
ARG A 178
 None
 1.40A 4kcnB-3bfgA:
undetectable		 4kcnB-3bfgA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 8 ARG A  65
SER A 189
ALA A 152
ARG A 153
 None
 1.06A 4lv9A-3bfgA:
undetectable
4lv9B-3bfgA:
undetectable		 4lv9A-3bfgA:
19.64
4lv9B-3bfgA:
19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		9 / 12 SER A  70
ASN A 104
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.47A 4n9kA-3bfgA:
42.1		 4n9kA-3bfgA:
42.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		9 / 12 SER A  70
ASN A 104
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.50A 4n9kB-3bfgA:
41.9		 4n9kB-3bfgA:
42.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 5 THR A 103
THR A 133
THR A  76
ASN A 170
 None
None
None
MER  A 301 (-2.6A)
 1.36A 4pgfB-3bfgA:
undetectable		 4pgfB-3bfgA:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 ASN A 104
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 MER  A 301 ( 4.1A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.43A 4pm5A-3bfgA:
46.9		 4pm5A-3bfgA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 ASN A 104
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.66A 4pm5A-3bfgA:
46.9		 4pm5A-3bfgA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 LYS A  73
ASN A 104
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
ALA A 237
 MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.51A 4pm7A-3bfgA:
46.8		 4pm7A-3bfgA:
75.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 LYS A  73
ASN A 104
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ALA A 237
 MER  A 301 ( 3.8A)
MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.68A 4pm7A-3bfgA:
46.8		 4pm7A-3bfgA:
75.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 ASN A 104
ASN A 132
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
ALA A 237
 MER  A 301 ( 4.1A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.49A 4pm9A-3bfgA:
47.0		 4pm9A-3bfgA:
75.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 ASN A 104
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ALA A 237
 MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.69A 4pm9A-3bfgA:
47.0		 4pm9A-3bfgA:
75.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 ALA A  79
THR A  76
ALA A  78
GLY A 146
SER A 154
 None
 1.03A 4qvlK-3bfgA:
undetectable
4qvlL-3bfgA:
undetectable		 4qvlK-3bfgA:
21.98
4qvlL-3bfgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 ALA A  79
THR A  76
ALA A  78
GLY A 146
SER A 154
 None
 1.02A 4qvlY-3bfgA:
undetectable
4qvlZ-3bfgA:
undetectable		 4qvlY-3bfgA:
21.98
4qvlZ-3bfgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 10 ALA A  79
THR A  76
ALA A  78
GLY A 146
SER A 154
 None
 1.02A 4qvmY-3bfgA:
undetectable
4qvmZ-3bfgA:
undetectable		 4qvmY-3bfgA:
21.85
4qvmZ-3bfgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 ALA A  79
THR A  76
ALA A  78
GLY A 146
SER A 154
 None
 1.01A 4qvwK-3bfgA:
undetectable
4qvwL-3bfgA:
undetectable		 4qvwK-3bfgA:
21.98
4qvwL-3bfgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 ALA A  79
THR A  76
ALA A  78
GLY A 146
SER A 154
 None
 1.01A 4qvwY-3bfgA:
undetectable
4qvwZ-3bfgA:
undetectable		 4qvwY-3bfgA:
21.98
4qvwZ-3bfgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 ALA A  79
THR A  76
ALA A  78
GLY A 146
SER A 154
 None
 1.00A 4qw1K-3bfgA:
undetectable
4qw1L-3bfgA:
undetectable		 4qw1K-3bfgA:
21.98
4qw1L-3bfgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 ALA A  79
THR A  76
ALA A  78
GLY A 146
SER A 154
 None
 1.03A 5bxnK-3bfgA:
undetectable
5bxnL-3bfgA:
undetectable		 5bxnK-3bfgA:
21.98
5bxnL-3bfgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 11 ALA A  79
THR A  76
ALA A  78
GLY A 146
SER A 154
 None
 1.03A 5bxnY-3bfgA:
undetectable
5bxnZ-3bfgA:
undetectable		 5bxnY-3bfgA:
21.98
5bxnZ-3bfgA:
21.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.47A 5ghyA-3bfgA:
41.7		 5ghyA-3bfgA:
42.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.47A 5ghyB-3bfgA:
41.7		 5ghyB-3bfgA:
42.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 11 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
ALA A 237
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
MER  A 301 (-4.2A)
 0.48A 5ghzA-3bfgA:
41.9		 5ghzA-3bfgA:
42.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 10 SER A  70
SER A 130
ASN A 132
ASN A 170
LYS A 234
THR A 235
GLY A 236
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.46A 5ghzB-3bfgA:
42.0		 5ghzB-3bfgA:
42.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.71A 5jsdA-3bfgA:
undetectable		 5jsdA-3bfgA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.71A 5jsdB-3bfgA:
undetectable		 5jsdB-3bfgA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.71A 5jsdC-3bfgA:
undetectable		 5jsdC-3bfgA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.71A 5jseA-3bfgA:
undetectable		 5jseA-3bfgA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.72A 5jseB-3bfgA:
undetectable		 5jseB-3bfgA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		3 / 3 THR A 181
SER A 182
TYR A 264
 None
 0.72A 5jseC-3bfgA:
undetectable		 5jseC-3bfgA:
16.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KMW_A_PNNA305_0
(BETA-LACTAMASE
TOHO-1)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		4 / 4 ASN A 104
PRO A 167
ASN A 170
ASP A 240
 MER  A 301 ( 4.1A)
None
MER  A 301 (-2.6A)
None
 0.42A 5kmwA-3bfgA:
46.8		 5kmwA-3bfgA:
77.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		3 / 3 ALA A  77
GLN A 128
THR A 126
 None
 0.61A 5n0oA-3bfgA:
undetectable		 5n0oA-3bfgA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 12 LEU A 211
ASP A 233
LEU A 162
VAL A 148
ALA A 125
 None
 1.12A 5uxdB-3bfgA:
undetectable		 5uxdB-3bfgA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MER  A 301 (-3.6A)
None
 0.69A 6b5yA-3bfgA:
40.7
6b5yB-3bfgA:
40.9		 6b5yA-3bfgA:
18.10
6b5yB-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.66A 6b5yB-3bfgA:
40.9		 6b5yB-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 10 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MER  A 301 (-3.6A)
None
 0.80A 6b5yC-3bfgA:
41.0
6b5yD-3bfgA:
41.0		 6b5yC-3bfgA:
18.10
6b5yD-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.71A 6b5yD-3bfgA:
41.0		 6b5yD-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MER  A 301 (-3.6A)
None
 0.68A 6b68A-3bfgA:
41.1
6b68B-3bfgA:
41.2		 6b68A-3bfgA:
18.10
6b68B-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.58A 6b68B-3bfgA:
41.2		 6b68B-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 10 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MER  A 301 (-3.6A)
None
 0.76A 6b68C-3bfgA:
40.9
6b68D-3bfgA:
41.0		 6b68C-3bfgA:
18.10
6b68D-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
None
 0.64A 6b68D-3bfgA:
41.0		 6b68D-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MER  A 301 (-3.6A)
None
 0.72A 6b69A-3bfgA:
40.9
6b69B-3bfgA:
41.0		 6b69A-3bfgA:
18.10
6b69B-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		9 / 12 SER A  70
SER A 130
PRO A 167
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
None
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.55A 6b69A-3bfgA:
40.9
6b69B-3bfgA:
41.0		 6b69A-3bfgA:
18.10
6b69B-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MER  A 301 (-3.6A)
None
 0.70A 6b69C-3bfgA:
40.9
6b69D-3bfgA:
41.0		 6b69C-3bfgA:
18.10
6b69D-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.42A 6b69D-3bfgA:
41.0		 6b69D-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MER  A 301 (-3.6A)
None
 0.76A 6b6aA-3bfgA:
40.8
6b6aB-3bfgA:
41.1		 6b6aA-3bfgA:
18.10
6b6aB-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		8 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.60A 6b6aB-3bfgA:
41.1		 6b6aB-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		5 / 9 PRO A 107
TYR A 129
THR A 215
THR A 216
ASP A 240
 None
None
None
MER  A 301 (-3.6A)
None
 0.71A 6b6aC-3bfgA:
40.8
6b6aD-3bfgA:
41.1		 6b6aC-3bfgA:
18.10
6b6aD-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.53A 6b6aD-3bfgA:
41.1		 6b6aD-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 SER A  70
SER A 130
PRO A 167
ASN A 170
LYS A 234
THR A 235
GLY A 236
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
None
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.53A 6b6cA-3bfgA:
41.1		 6b6cA-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		6 / 12 SER A  70
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.46A 6b6dA-3bfgA:
40.7		 6b6dA-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		6 / 12 SER A  70
SER A 130
ASN A 170
LYS A 234
THR A 235
GLY A 236
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.68A 6b6dA-3bfgA:
40.7		 6b6dA-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 SER A  70
SER A 130
ASN A 170
THR A 216
LYS A 234
THR A 235
GLY A 236
 MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
 0.40A 6b6eA-3bfgA:
40.9		 6b6eA-3bfgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		9 / 12 CSS A  69
SER A  70
SER A 130
PRO A 167
ASN A 170
LYS A 234
THR A 235
GLY A 236
ASP A 240
 MER  A 301 (-4.6A)
MER  A 301 (-1.3A)
MER  A 301 (-2.6A)
None
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.5A)
MER  A 301 (-3.0A)
None
 0.56A 6b6fA-3bfgA:
40.7		 6b6fA-3bfgA:
18.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 3bfg CLASS A
BETA-LACTAMASE SED1
(Citrobacter
sedlakii) 		7 / 12 ASN A 104
SER A 130
ASN A 132
ASN A 170
THR A 216
LYS A 234
GLY A 236
 MER  A 301 ( 4.1A)
MER  A 301 (-2.6A)
MER  A 301 (-3.2A)
MER  A 301 (-2.6A)
MER  A 301 (-3.6A)
MER  A 301 (-3.2A)
MER  A 301 (-3.0A)
 0.38A 6c79A-3bfgA:
47.4		 6c79A-3bfgA:
72.84