SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bfx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3bfx SULFOTRANSFERASE 1C2
(Homo
sapiens) 		4 / 7 GLY A 179
THR A 112
PHE A 191
PHE A 193
 None
 1.14A 2qx4A-3bfxA:
2.3
2qx4B-3bfxA:
2.3		 2qx4A-3bfxA:
20.26
2qx4B-3bfxA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3bfx SULFOTRANSFERASE 1C2
(Homo
sapiens) 		4 / 5 VAL A 208
LEU A 190
LEU A 127
ILE A 197
 None
 0.95A 4a9jB-3bfxA:
undetectable		 4a9jB-3bfxA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3bfx SULFOTRANSFERASE 1C2
(Homo
sapiens) 		4 / 5 VAL A 208
LEU A 190
LEU A 127
ILE A 197
 None
 0.81A 4a9jC-3bfxA:
undetectable		 4a9jC-3bfxA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bfx SULFOTRANSFERASE 1C2
(Homo
sapiens) 		3 / 3 PHE A 126
VAL A  59
ILE A  55
 None
 0.53A 4emaA-3bfxA:
undetectable		 4emaA-3bfxA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 3bfx SULFOTRANSFERASE 1C2
(Homo
sapiens) 		5 / 12 ILE A  58
TRP A  54
LEU A 192
VAL A 129
ALA A 130
 None
A3P  A4000 (-3.2A)
None
None
None
 1.18A 4foxD-3bfxA:
undetectable		 4foxD-3bfxA:
16.72