SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 3bg1 PROTEIN SEC13
HOMOLOG
(Homo
sapiens) 		3 / 3 TRP A 158
VAL A 218
TRP A 220
 None
 1.36A 1gmkC-3bg1A:
undetectable
1gmkD-3bg1A:
undetectable		 1gmkC-3bg1A:
4.15
1gmkD-3bg1A:
4.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 3bg1 PROTEIN SEC13
HOMOLOG
(Homo
sapiens) 		5 / 12 ILE A 129
GLY A 152
VAL A 106
SER A 105
ASN A 147
 None
 1.16A 1sg9A-3bg1A:
undetectable		 1sg9A-3bg1A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3bg1 PROTEIN SEC13
HOMOLOG
(Homo
sapiens) 		5 / 11 ALA A 210
GLY A 238
ILE A 191
VAL A 240
SER A 233
 None
 1.04A 3gyqB-3bg1A:
undetectable		 3gyqB-3bg1A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3bg1 PROTEIN SEC13
HOMOLOG
(Homo
sapiens) 		4 / 8 SER A 233
ALA A 232
HIS A 211
LEU A 257
 None
 1.13A 5dzkd-3bg1A:
undetectable
5dzkr-3bg1A:
undetectable		 5dzkd-3bg1A:
20.75
5dzkr-3bg1A:
1.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3bg1 PROTEIN SEC13
HOMOLOG
(Homo
sapiens) 		4 / 4 ILE A  85
ILE A  73
ARG A  87
LEU A 132
 None
 1.06A 5dzkh-3bg1A:
undetectable
5dzkn-3bg1A:
undetectable
5dzkv-3bg1A:
undetectable		 5dzkh-3bg1A:
21.94
5dzkn-3bg1A:
21.94
5dzkv-3bg1A:
1.52