SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bg2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 11 LEU A  87
LEU A  94
GLU A   5
MET A   2
ILE A 329
 None
 1.28A 1g50A-3bg2A:
undetectable		 1g50A-3bg2A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 6 ALA A 111
LEU A  29
ASP A 104
LEU A   8
 None
 0.98A 1mt1D-3bg2A:
undetectable
1mt1E-3bg2A:
undetectable		 1mt1D-3bg2A:
13.96
1mt1E-3bg2A:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 6 SER A 215
ILE A 417
ALA A 421
THR A 425
 None
 0.78A 1w0gA-3bg2A:
undetectable		 1w0gA-3bg2A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 5 PHE A  31
THR A 185
LEU A 245
ALA A 107
 None
 1.39A 2e1qD-3bg2A:
undetectable		 2e1qD-3bg2A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 ALA A 110
ALA A 112
GLY A  80
GLY A  76
TYR A 100
 None
 1.15A 2igtA-3bg2A:
undetectable		 2igtA-3bg2A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 ALA A 110
ALA A 112
GLY A  80
GLY A  76
TYR A 100
 None
 1.14A 2igtB-3bg2A:
undetectable		 2igtB-3bg2A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 7 TYR A 210
GLN A 214
TYR A 413
ILE A 131
 None
 1.25A 2ph9A-3bg2A:
undetectable
2ph9B-3bg2A:
undetectable		 2ph9A-3bg2A:
20.40
2ph9B-3bg2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 7 GLN A 214
SER A 215
TYR A 210
CYH A 420
 None
 1.34A 2xz5D-3bg2A:
undetectable
2xz5E-3bg2A:
undetectable		 2xz5D-3bg2A:
20.27
2xz5E-3bg2A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 8 ALA A 371
TYR A 435
GLY A 372
ILE A 375
 None
 0.92A 2zm9A-3bg2A:
undetectable		 2zm9A-3bg2A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		3 / 3 TYR A 210
LEU A 230
LYS A 231
 None
 0.76A 3sueD-3bg2A:
undetectable		 3sueD-3bg2A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 SER A 215
GLN A 170
GLU A 216
GLY A 160
ALA A 162
 None
 1.11A 3tegA-3bg2A:
undetectable		 3tegA-3bg2A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 ILE A 315
ILE A 260
CYH A 256
ILE A 255
ALA A 308
 None
 0.99A 3uj7A-3bg2A:
undetectable		 3uj7A-3bg2A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 7 GLN A  24
ARG A  19
GLY A  30
VAL A  33
 None
 0.93A 4a3uB-3bg2A:
undetectable		 4a3uB-3bg2A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 5 HIS A  63
GLN A  52
SER A  69
VAL A  72
 None
 1.49A 4a99D-3bg2A:
1.3		 4a99D-3bg2A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 5 HIS A 243
LEU A 338
LEU A  79
ASP A 254
 None
 1.31A 4aqlA-3bg2A:
undetectable		 4aqlA-3bg2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 GLY A 164
ALA A 162
ARG A  65
ILE A 118
VAL A 167
 None
 1.17A 4azsA-3bg2A:
undetectable		 4azsA-3bg2A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 GLY A 164
ALA A 162
ARG A  65
ILE A 118
VAL A 167
 None
 1.20A 4azwA-3bg2A:
undetectable		 4azwA-3bg2A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 GLY A 211
LEU A 230
GLY A 228
PRO A 244
LEU A   7
 None
 1.07A 4fp9F-3bg2A:
undetectable		 4fp9F-3bg2A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 GLY A 211
LEU A 230
GLY A 228
PRO A 244
LEU A   7
 None
 1.06A 4fzvA-3bg2A:
undetectable		 4fzvA-3bg2A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 LEU A  94
GLU A   5
MET A   2
ILE A 329
LEU A 245
 None
 1.04A 4j26A-3bg2A:
undetectable		 4j26A-3bg2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 LEU A  94
GLU A   5
MET A   2
ILE A 329
LEU A 245
 None
 1.04A 4j26B-3bg2A:
undetectable		 4j26B-3bg2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		3 / 3 ARG A 180
ASP A  15
ARG A  37
 None
 0.84A 4mx0A-3bg2A:
undetectable		 4mx0A-3bg2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		4 / 8 ILE A  22
TYR A 100
LEU A  29
PHE A  31
 None
 0.87A 4qopC-3bg2A:
undetectable		 4qopC-3bg2A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 ASP A  36
ALA A 115
GLY A  30
LEU A 168
GLY A 106
 None
 0.99A 5i73A-3bg2A:
undetectable		 5i73A-3bg2A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3bg2 DGTP
TRIPHOSPHOHYDROLASE
(Leeuwenhoekiella
blandensis) 		5 / 12 VAL A 249
ASP A 117
HIS A 116
ALA A 112
LEU A 168
 None
 1.18A 6ew0F-3bg2A:
undetectable		 6ew0F-3bg2A:
10.88